Results 1 to 10 of about 1,059 (142)

The application of shotgun metagenomics to the diagnosis of granulomatous amoebic encephalitis due to Balamuthia mandrillaris: a case report [PDF]

BMC Neurology, 2021
Background Granulomatous amoebic encephalitis (GAE) is an infrequent and fatal infectious disease worldwide. Antemortem diagnosis in this condition is very difficult because clinical manifestations and neuroimaging are nonspecific. Case presentation A 60-
Shota Hirakata, Yusuke Sakiyama, Akiko Yoshimura, Mei Ikeda, Katsunori Takahata, Yuichi Tashiro, Michiyoshi Yoshimura, Hitoshi Arata, Hajime Yonezawa, Mari Kirishima, Michiyo Higashi, Miho Hatanaka, Takuro Kanekura, Kenji Yagita, Eiji Matsuura, Hiroshi Takashima   +15 more
doaj   +5 more sources

A patient with granulomatous amoebic encephalitis caused by Balamuthia mandrillaris survived with two excisions and medication [PDF]

BMC Infectious Diseases, 2022
Background Granulomatous amoebic encephalitis (GAE) is a rare central nervous system infection caused by the Balamuthia mandrillaris or Acanthamoeba species.
Limei Peng, Quan Zhou, Yu Wu, Xiaoli Cao, Zili Lv, Minghua Su, Yachun Yu, Wen Huang   +7 more
doaj   +6 more sources

Unmasking Balamuthia mandrillaris Through PCR in a Case of Multifocal Brain Lesions [PDF]

Case Reports in Infectious Diseases
Balamuthia mandrillaris is a rare free-living amoeba that causes granulomatous amoebic encephalitis (GAE), a frequently fatal central nervous system infection.
Moamen Al Zoubi, Garry Jean-Louis, Kelly Sylvain, Cara Moll, Alison Schwartz VanEperen, Ammar Nasrallah, Amanda Carlson, Julie Duval, Norah Grady Letendre   +8 more
doaj   +3 more sources

Application of ventriculoscopy in granulomatous amoebic encephalitis: a case report in China and literature review [PDF]

Frontiers in Medicine
Balamuthia mandrillaris is a kind of brain-eating amoeba leading to granulomatous amoebic encephalitis (GAE) with a high mortality rate and limited effective treatment options. Its underlying pathological mechanisms are still poorly understood.
Zequan Zheng, Zequan Zheng, Fajun Chen, Lulu Qin, Aili Lu, Haoyou Xu, Min Zhao, Yuanqi Zhao   +7 more
doaj   +4 more sources

Mitochondrial genome diversity of Balamuthia mandrillaris revealed by a fatal case of granulomatous amoebic encephalitis [PDF]

Frontiers in Microbiology, 2023
IntroductionBalamuthia (B.) mandrillaris is a free-living amoeba that can cause rare yet fatal granulomatous amoebic encephalitis (GAE). However, efficacious treatment for GAE is currently unavailable, especially when genomic studies on B.
Cherie Tsz-Yiu Law, Cherie Tsz-Yiu Law, Thirapa Nivesvivat, Qing Xiong, Qing Xiong, Kasem Kulkeaw, Ling Shi, Ling Shi, Pichet Ruenchit, Detchvijitr Suwanpakdee, Piradee Suwanpakdee, Nongnat Tongkrajang, Patsharaporn T. Sarasombath, Stephen Kwok-Wing Tsui, Stephen Kwok-Wing Tsui   +14 more
doaj   +4 more sources

Rapidly Progressive Granulomatous Amoebic Encephalitis in a Diabetic Individual. [PDF]

Cureus, 2021
We present a case of rapidly progressive granulomatous amoebic encephalitis caused by Balamuthia mandrillaris in an individual with diabetes mellitus. Our patient presented with occipital headache, blurry vision, confusion, and gait imbalance of one week's duration. Brain imaging revealed numerous peripheral ring-enhancing lesions concerning malignancy.
Paudel AC, Patel N, Quang J, Casella C, Sigal A, Parajuli P, Oladunjoye O, Oke IO, Khanal S, Bhattarai K.   +9 more
europepmc   +4 more sources

A case report of granulomatous amoebic encephalitis by Group 1 Acanthamoeba genotype T18 diagnosed by the combination of morphological examination and genetic analysis [PDF]

Diagnostic Pathology, 2018
Background The diagnosis of granulomatous amoebic encephalitis is challenging for clinicians because it is a rare and lethal disease. Previous reports have indicated that Acanthamoeba with some specific genotypes tend to cause the majority of human ...
Takahiro Matsui, Tetsuo Maeda, Shinsuke Kusakabe, Hideyuki Arita, Kenji Yagita, Eiichi Morii, Yuzuru Kanakura   +6 more
doaj   +2 more sources

A clinical case report of Balamuthia granulomatous amoebic encephalitis in a non-immunocompromised patient and literature review. [PDF]

BMC Infect Dis, 2023
Abstract Background Balamuthia granulomatous amoebic encephalitis (GAE) is a peculiar parasitic infectious disease of the central nervous system, about 39% of the infected Balamuthia GAE patients were found to be immunocompromised and is extremely rare clinically.
Liu J, Zhang W, Wu S, Zeng T, Luo F, Jiang Q, Yang R.   +6 more
europepmc   +4 more sources

An Acute Case of Granulomatous Amoebic Encephalitis-Balamuthia mandrillaris Infection. [PDF]

Intern Med, 2018
A 74-year-old woman who exhibited drowsiness was referred to our hospital. Enhanced head magnetic resonance imaging (MRI) revealed multiple ring-enhancing lesions and lesions showing partial mild hemorrhaging. The patient gradually progressed to a comatose condition with notable brain deterioration of unknown cause on follow-up MRI.
Takei K, Toyoshima M, Nakamura M, Sato M, Shimizu H, Inoue C, Shimizu Y, Yagita K.   +7 more
europepmc   +3 more sources

Imaging findings of Balamuthia mandrillaris amoebic encephalitis in 2 cases with different prognosis and literature review [PDF]

BMC Neurology
Introduction Balamuthia mandrillaris amoebic encephalitis is a rare granulomatous amoebic encephalitis caused by infection with Balamuthia mandrillaris with a fatality rate over 90%.
Yanjia Chen, Tingting Zhang, Haiyan Lou
doaj   +2 more sources