Results 41 to 50 of about 71,427 (180)

Optic neuritis associated with seronegative autoimmune encephalitis: a case report [PDF]

, 2023
Optic neuritis is an inflammatory demyelinating disorder that primarily affects the optic nerve and is often associated with multiple sclerosis. While it is rare for optic neuritis to be accompanied by autoimmune encephalitis, it can occur in some cases.
Yonghyun Lee, Ho-Won Lee, Ji-Ye Jeon, Hyungseok Hah   +3 more
core   +2 more sources

Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment

Parasite, 2021
Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming, Ko Pin-Ju, Huang Chao-Li, Wen Po-Wei, Chen Chun-Hsien, Shih Min-Hsiu, Lin Wei-Chen, Huang Fu-Chin   +7 more
doaj   +1 more source

Granulomatous Amoebic Encephalitis: Clinical Diagnosis and Management [PDF]

American Journal of Infectious Diseases, 2005
Granulomatous amoebic encephalitis (GAE) is a serious human disease with fatal consequences. With the mortality rate of more than 90%, it is not surprising that the majority of GAE infections are identified at the post-mortem stage. The most distressing aspect is that the high level of mortality is attributed to lack of awareness.
openaire   +1 more source

Autoimmune encephalitis [PDF]

, 2021
The objective of this paper is to evaluate available evidence for each step in autoimmune encephalitis management and provide expert opinion when evidence is lacking.
Russell C. Dale, Benavides, David R, Yuebing Li, Titulaer, Maarten; id_orcid, Beau Ances, Flanagan, Eoin P., Dale, Russell C., Michael Bradshaw, Titulaer, Maarten J, Soon-Tae Lee, David R. Benavides, Arun Venkatesan, Ian Rossman, Morse, Anne Marie, Rae-Grant, Alexander, Lee, Soon-Tae, Abboud, Hesham, Avi Gadoth, Bradshaw, Michael, Li, Yuebing, Maarten J. Titulaer, Probasco, John C., Matiello, Marcelo, Soon Tae Lee, Autoimmune Encephalitis Alliance Clinicians Network, Eoin P. Flanagan, Beau M. Ances, Sarah Schmitt, Sarosh Irani, John C. Probasco, Titulaer, Maarten J., Dale, Russell C, Marcelo Matiello, Galeno Rojas, Rossman, Ian, George, Pravin, Jammoul, Adham, John Calvin Probasco, David R Benavides, Steven Vernino, Irani, Sarosh R., Probasco, John, Gadoth, Avi, Hesham Abboud, Christo, Paulo Pereira, Irani, Sarosh, Sarosh R. Irani, M.J. (Maarten) Titulaer, Lee, Soon Tae, Vernino, Steven, Schmitt, Sarah, Grebenciucova, Elena, Sean J. Pittock, Probasco, John C, Elena Grebenciucova, Benavides, David R., Maarten Titulaer, Alexander Rae-Grant, Mireya Fernandez-Fournier, Flanagan, Eoin P, Rojas, Galeno, Titulaer, Maarten J.; id_orcid, Pittock, Sean J, Adham Jammoul, Pravin George, Titulaer, Maarten, Fernandez-Fournier, Mireya, Anne Marie Morse, Venkatesan, Arun, Paulo Pereira Christo, Irani, Sarosh R, Ances, Beau, Pittock, Sean J.   +72 more
core   +1 more source

Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae

Clinical and Translational Science, 2021
Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become pathogenic and ...
Alexandre Taravaud, Zineb Fechtali‐Moute, Philippe M. Loiseau, Sébastien Pomel   +3 more
doaj   +1 more source

Autoimmunity in the Mediation of Granulomatous Amoebic Encephalitis: Implications for Therapy [PDF]

, 2011
Acanthamoeba spp. are free-living amoebae that are ubiquitous in the environment. Most healthy individuals carry Acanthamoeba-reactive antibodies, suggesting constant exposure to amoebae. In spite of the high prevalence of the amoebae, the incidence of diseases caused by Acanthamoeba is very low.
Chandirasegaran Massilamany, Jay Reddy
openaire   +1 more source

Diagnosis of Infections Caused by Pathogenic Free-Living Amoebae

Interdisciplinary Perspectives on Infectious Diseases, 2009
Naegleria fowleri, Acanthamoeba spp., Balamuthia mandrillaris, and Sappinia sp. are pathogenic free-living amoebae. N. fowleri causes Primary Amoebic Meningoencephalitis, a rapidly fatal disease of the central nervous system, while Acanthamoeba spp.
Bruno da Rocha-Azevedo, Herbert B. Tanowitz, Francine Marciano-Cabral   +2 more
doaj   +1 more source

Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris

Antibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and granulomatous amoebic encephalitis (GAE), the fatal ...
Ruqaiyyah Siddiqui, Anania Boghossian, Bushra Khatoon, Muhammad Kawish, Ahmad M. Alharbi, Muhammad Raza Shah, Hasan Alfahemi, Naveed Ahmed Khan   +7 more
doaj   +1 more source

Isolation and identification of free-living amoeba from contact lenses: Thermal and osmotic tolerance in relation to their pathogenicity. [PDF]

Assiut University Journal of Multidisciplinary Scientific Research, 2022
Free-living amoeba (FLA) such as Acanthamoeba spp., Naegleria fowleri, Balamuthia mandrillaris, and Sappinia diploidea are widely distributed natural and human-made environments which may cause human diseases.  For example, N.
doaj   +1 more source

Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism [PDF]

, 2005
Granulomatous amoebic encephalitis due to Acanthamoeba castellanii is a serious human infection with fatal consequences, but it is not clear how the circulating amoebae interact with the blood-brain barrier and transmigrate into the central nervous ...
S. Jayasekera, N. A. Khan, M. Stins, K. S. Kim, Alsam, S., Stins, M., Khan, Naveed Ahmed, Sissons, J., J. Sissons, Kim, K.S., Jayasekera, S., S. Alsam   +11 more
core   +1 more source