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Balamuthia mandrillaris is one cause of a rare and severe brain infection called granulomatous amoebic encephalitis (GAE), which has a mortality rate of >90%. Diagnosis of Balamuthia GAE is difficult because symptoms are non-specific.
Juan Hu +10 more
doaj +1 more source
Free-living amoebae (FLA) are protozoa widely distributed in the environment, found in a great diversity of terrestrial biomes. Some genera of FLA are linked to human infections.
Alejandro Otero-Ruiz +5 more
doaj +1 more source
Acanthamoeba castellanii genotype T4 is a clinically significant free-living amoeba that causes granulomatous amoebic encephalitis and amoebic keratitis in human beings.
Gerardo Ramírez-Rico +7 more
doaj +1 more source
Diagnosing Balamuthia mandrillaris encephalitis via next-generation sequencing in a 13-year-old girl
Balamuthia amoebic encephalitis has a subacute-to-chronic course and is almost invariably fatal owing to delayed diagnosis and a lack of effective therapy.
Xia Wu +6 more
doaj +1 more source
Studies of Spanish influenza and encephalitis lethargica. [PDF]
PhDConcomitant with the Spanish influenza and extending to the 1920s encephalitis lethargica (EL), also termed von Economo's disease or sleepy sickness, occurred in epidemic proportion.
Lo, Lily Yen-Ching
core +4 more sources
Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells [PDF]
The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Rogers, Claire +18 more
core +1 more source
Balamuthia mandrillaris encephalitis in an uncontrolled diabetic patient
Balamuthia mandrillaris is a free-living amoeba that may result in a disseminated infection of the central nervous system called granulomatous amoebic encephalitis.
Valli Mani, Eric Hudgins
doaj +1 more source
Table_1_Pathogenic free-living amoebic encephalitis from 48 cases in China: A systematic review.DOCX
BackgroundFree-living amoebae (FLA) including Naegleria fowleri, Acanthamoeba spp., and Balamuthia mandrillaris can become pathogenic and cause severe cerebral infections, named primary amoebic meningoencephalitis (PAM), granulomatous amoebic ...
Fei-Fei Chen (3383549) +4 more
core +1 more source
Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine
We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis.
Alexander C. Aichelburg +8 more
doaj +1 more source
Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases
Acanthamoeba are ubiquitous free-living amoeba. Acanthamoeba infections cause necrotizing vasculitis, resulting in vessel thrombosis and cerebral infarction. Acanthamoeba CNS infections, though uncommon, are associated with high mortality.
Sohini Das +6 more
doaj +1 more source

