Results 31 to 40 of about 1,079 (146)

Guidelines for the purification and characterization of extracellular vesicles of parasites

Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra, Patrícia Xander, Daniel Alfandari, George Dong, Iris Aparici‐Herraiz, Irit Rosenhek‐Goldian, Mehrdad Shokouhy, Melisa Gualdron‐Lopez, Nicholy Lozano, Nuria Cortes‐Serra, Paula Abou Karam, Paula Meneghetti, Rafael Pedro Madeira, Ziv Porat, Rodrigo Pedro Soares, Adriana Oliveira Costa, Sima Rafati, Anabela‐Cordeiro da Silva, Nuno Santarém, Christopher Fernandez‐Prada, Marcel I. Ramirez, Dolores Bernal, Antonio Marcilla, Vera Lucia Pereira‐Chioccola, Lysangela Ronalte Alves, Hernando Del Portillo, Neta Regev‐Rudzki, Igor Correia de Almeida, Sergio Schenkman, Martin Olivier, Ana Claudia Torrecilhas   +30 more
wiley   +1 more source

Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

Emerging Infectious Diseases, 2008
We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis.
Alexander C. Aichelburg, Julia Walochnik, Ojan Assadian, Helmut Prosch, Andrea Steuer, Gedeon Perneczky, Govinda S. Visvesvara, Horst Aspöck, Norbert Vetter   +8 more
doaj   +1 more source

Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases

Journal of Family Medicine and Primary Care, 2020
Acanthamoeba are ubiquitous free-living amoeba. Acanthamoeba infections cause necrotizing vasculitis, resulting in vessel thrombosis and cerebral infarction. Acanthamoeba CNS infections, though uncommon, are associated with high mortality.
Sohini Das, Karthik Gunasekaran, Sitara S. R Ajjampur, Dilip Abraham, Tina George, M Asisha Janeela, Ramya Iyadurai   +6 more
doaj   +1 more source

Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment

Parasite, 2021
Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming, Ko Pin-Ju, Huang Chao-Li, Wen Po-Wei, Chen Chun-Hsien, Shih Min-Hsiu, Lin Wei-Chen, Huang Fu-Chin   +7 more
doaj   +1 more source

Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae

Clinical and Translational Science, 2021
Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become pathogenic and ...
Alexandre Taravaud, Zineb Fechtali‐Moute, Philippe M. Loiseau, Sébastien Pomel   +3 more
doaj   +1 more source

Granulomatous Amoebic Encephalitis: Clinical Diagnosis and Management [PDF]

American Journal of Infectious Diseases, 2005
Granulomatous amoebic encephalitis (GAE) is a serious human disease with fatal consequences. With the mortality rate of more than 90%, it is not surprising that the majority of GAE infections are identified at the post-mortem stage. The most distressing aspect is that the high level of mortality is attributed to lack of awareness.
openaire   +1 more source

Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris

Antibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and granulomatous amoebic encephalitis (GAE), the fatal ...
Ruqaiyyah Siddiqui, Anania Boghossian, Bushra Khatoon, Muhammad Kawish, Ahmad M. Alharbi, Muhammad Raza Shah, Hasan Alfahemi, Naveed Ahmed Khan   +7 more
doaj   +1 more source

Diagnosis of Infections Caused by Pathogenic Free-Living Amoebae

Interdisciplinary Perspectives on Infectious Diseases, 2009
Naegleria fowleri, Acanthamoeba spp., Balamuthia mandrillaris, and Sappinia sp. are pathogenic free-living amoebae. N. fowleri causes Primary Amoebic Meningoencephalitis, a rapidly fatal disease of the central nervous system, while Acanthamoeba spp.
Bruno da Rocha-Azevedo, Herbert B. Tanowitz, Francine Marciano-Cabral   +2 more
doaj   +1 more source

Isolation and identification of free-living amoeba from contact lenses: Thermal and osmotic tolerance in relation to their pathogenicity. [PDF]

Assiut University Journal of Multidisciplinary Scientific Research, 2022
Free-living amoeba (FLA) such as Acanthamoeba spp., Naegleria fowleri, Balamuthia mandrillaris, and Sappinia diploidea are widely distributed natural and human-made environments which may cause human diseases.  For example, N.
doaj   +1 more source

Autoimmunity in the Mediation of Granulomatous Amoebic Encephalitis: Implications for Therapy [PDF]

, 2011
Acanthamoeba spp. are free-living amoebae that are ubiquitous in the environment. Most healthy individuals carry Acanthamoeba-reactive antibodies, suggesting constant exposure to amoebae. In spite of the high prevalence of the amoebae, the incidence of diseases caused by Acanthamoeba is very low.
Chandirasegaran Massilamany, Jay Reddy
openaire   +1 more source