Objectives: To characterize a genetically distinct Balamuthia lineage causing fatal granulomatous amoebic encephalitis (GAE) in a 10-month-old infant and highlight diagnostic challenges compounded by SARS-COV-2 infection comorbidity. Methods: Case report
Junrong Liang +2 more
exaly +6 more sources
Rapidly Progressive Granulomatous Amoebic Encephalitis in a Diabetic Individual. [PDF]
We present a case of rapidly progressive granulomatous amoebic encephalitis caused by Balamuthia mandrillaris in an individual with diabetes mellitus. Our patient presented with occipital headache, blurry vision, confusion, and gait imbalance of one week's duration. Brain imaging revealed numerous peripheral ring-enhancing lesions concerning malignancy.
Paudel AC +9 more
europepmc +5 more sources
A clinical case report of Balamuthia granulomatous amoebic encephalitis in a non-immunocompromised patient and literature review. [PDF]
Abstract Background Balamuthia granulomatous amoebic encephalitis (GAE) is a peculiar parasitic infectious disease of the central nervous system, about 39% of the infected Balamuthia GAE patients were found to be immunocompromised and is extremely rare clinically.
Liu J +6 more
europepmc +5 more sources
Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report [PDF]
Abstract Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft.
Zangeneh Tirdad
exaly +5 more sources
Acanthamoeba is a free-living amoeba genus able to cause severe infections, such as Granulomatous amoebic encephalitis (GAE), epithelial disorders and a sight-threatening disease called Acanthamoeba keratitis (AK) [...]
María Reyes-Batlle +4 more
doaj +2 more sources
Granulomatous amoebic encephalitis: ghost response of an immunocompromised host?
Naegleria fowleri, Acanthamoeba and Balamuthia mandrillaris spp. are known to cause fatal amoebic encephalitis. Here, I attempt to draw attention to these cases, which are reported as ‘granulomatous amoebic encephalitis’ (GAE), and their occurrence in immunocompromised individuals and patients with AIDS.
Baig, Abdul Mannan
openaire +3 more sources
Balamuthia mandrillaris encephalitis in an uncontrolled diabetic patient
Balamuthia mandrillaris is a free-living amoeba that may result in a disseminated infection of the central nervous system called granulomatous amoebic encephalitis.
Valli Mani, Eric Hudgins
doaj +2 more sources
Serum Antibodies toBalamuthia mandrillaris,a Free‐Living Amoeba Recently Demonstrated to Cause Granulomatous Amoebic Encephalitis [PDF]
Free-living amoebae cause three well-defined disease entities: a rapidly fatal primary meningoencephalitis, a chronic granulomatous amoebic encephalitis (GAE), and a chronic amoebic keratitis. GAE occurs in immunocompromised persons. Recently, another type of free-living amoeba, Balamuthia mandrillaris, has been shown to cause GAE.
Huang, Z., Ferrante, A., Carter, R.
openaire +5 more sources
Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine
We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis.
Alexander C. Aichelburg +8 more
doaj +2 more sources
A case report of Balamuthia mandrillaris encephalitis
Balamuthia amoebic encephalitis (BAE) is a rare and severe parasitic infection of the central nervous system. Its delayed diagnosis and treatment are often due to the lack of specific clinical manifestations and its poor prognosis.
Zhen Li +4 more
doaj +2 more sources

