Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. [PDF]
Abstract Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft.
Salameh A +3 more
europepmc +6 more sources
Objectives: To characterize a genetically distinct Balamuthia lineage causing fatal granulomatous amoebic encephalitis (GAE) in a 10-month-old infant and highlight diagnostic challenges compounded by SARS-COV-2 infection comorbidity. Methods: Case report
Zhongqiu Teng +11 more
doaj +5 more sources
Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier. [PDF]
A 38-year-old male immunocompetent soldier developed generalized seizures. He underwent surgical debulking and a progressive demyelinating pseudotumor was identified. Serology and molecular testing confirmed a diagnosis of granulomatous amoebic encephalitis caused by Acanthamoeba sp. in this immunocompetent male.
Webster D +7 more
europepmc +4 more sources
Pathogenic free-living amoebic encephalitis from 48 cases in China: A systematic review
BackgroundFree-living amoebae (FLA) including Naegleria fowleri, Acanthamoeba spp., and Balamuthia mandrillaris can become pathogenic and cause severe cerebral infections, named primary amoebic meningoencephalitis (PAM), granulomatous amoebic ...
Xiang-Ting Chen +4 more
doaj +3 more sources
Fatal amoebic meningoencephalitis caused by Balamuthia mandrillaris in Pongo pygmaeus and first case report in Pan troglodytes verus [PDF]
Balamuthia mandrillaris is an amoeba that can cause granulomatous amoebic encephalitis (GAE) as well as lung and skin infections in both humans and animals. Studies on B. mandrillaris-related GAE cases have increased in recent years. This amoeba has been
Rubén L. Rodríguez-Expósito +36 more
doaj +2 more sources
Successful Treatment of Granulomatous Amoebic Encephalitis with Combination Antimicrobial Therapy
Granulomatous amoebic encephalitis (GAE) is a rare but fatal infection. Due to its nonspecific symptoms and laboratory and neuroradiological findings, it is rarely diagnosed antemortem. We herein present the case of a 72-year-old Japanese woman who was diagnosed with GAE following the detection of a pathogen similar to Balamuthia mandrillaris under a ...
Kato, Hideki +5 more
openaire +5 more sources
Granulomatous amoebic encephalitis presenting as a solitary mass lesion
Abstract Granulomatous amoebic encephalitis is a rare progressive infectious disease of the central nervous system with a high mortality rate. It usually presents as multiple ring-enhancing lesions in the brain with surrounding edema evident, while the granulomatous amoeba encephalitis reported in this case is manifested as a solitary mass in the ...
Nian Xia Fu +3 more
openaire +3 more sources
Repurposing CNS drugs Zonisamide and Perampanel conjugated with silver nanoparticles as an anti-amoebic agent in combating Granulomatous Amebic Encephalitis (GAE) and Primary Amebic Meningoencephalitis (PAM) infection caused by Acanthamoeba castellanii and Naegleria Fowleri [PDF]
Acanthamoeba castellanii (A. castellanii) and Naegleria fowleri (N. fowleri) are free-living amoebae that cause Granulomatous Amoebic Encephalitis (GAE) and Primary Amoebic Meningoencephalitis (PAM), respectively rare but often fatal central nervous ...
Devandran Apparasamy +8 more
doaj +2 more sources
Balamuthia amoebic encephalitis directly causing intracranial infection: A case report [PDF]
Balamuthia amoebic encephalitis (BAE) is a rare and often fatal central nervous system (CNS) infection caused by Balamuthia mandrillaris, a free-living amoeba typically found in soil and water. This organism can invade the brain directly, bypassing other
Yuhan Liang +5 more
doaj +2 more sources
Genotyping of <i>Acanthamoeba</i> From Different Wards of Gonabad Bohlool Hospital, Northeastern Iran. [PDF]
Background: Acanthamoeba is a free‐living amoeba that is widely found in nature in different environments such as soil, water, and dust. This parasite is the cause of amoebic keratitis and granulomatous amoebic encephalitis. This study is aimed at investigating the prevalence and genotypes of Acanthamoeba in different wards of Gonabad Bohlool Hospital,
Salehi M +4 more
europepmc +2 more sources

