Balamuthia mandrillaris encephalitis in an uncontrolled diabetic patient
Balamuthia mandrillaris is a free-living amoeba that may result in a disseminated infection of the central nervous system called granulomatous amoebic encephalitis.
Valli Mani, Eric Hudgins
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Guidelines for the purification and characterization of extracellular vesicles of parasites
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra +30 more
wiley +1 more source
Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine
We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous amoebic encephalitis, and underlying miliary tuberculosis and tuberculous meningitis.
Alexander C. Aichelburg +8 more
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Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases
Acanthamoeba are ubiquitous free-living amoeba. Acanthamoeba infections cause necrotizing vasculitis, resulting in vessel thrombosis and cerebral infarction. Acanthamoeba CNS infections, though uncommon, are associated with high mortality.
Sohini Das +6 more
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Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming +7 more
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Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae
Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become pathogenic and ...
Alexandre Taravaud +3 more
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Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris
Naegleria fowleri and Balamuthia mandrillaris are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and granulomatous amoebic encephalitis (GAE), the fatal ...
Ruqaiyyah Siddiqui +7 more
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Diagnosis of Infections Caused by Pathogenic Free-Living Amoebae
Naegleria fowleri, Acanthamoeba spp., Balamuthia mandrillaris, and Sappinia sp. are pathogenic free-living amoebae. N. fowleri causes Primary Amoebic Meningoencephalitis, a rapidly fatal disease of the central nervous system, while Acanthamoeba spp.
Bruno da Rocha-Azevedo +2 more
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Isolation and identification of free-living amoeba from contact lenses: Thermal and osmotic tolerance in relation to their pathogenicity. [PDF]
Free-living amoeba (FLA) such as Acanthamoeba spp., Naegleria fowleri, Balamuthia mandrillaris, and Sappinia diploidea are widely distributed natural and human-made environments which may cause human diseases. For example, N.
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Comparative neuropathology of Balamuthia mandrillaris infection across species
Balamuthia mandrillaris is a free-living amoeba that causes granulomatous amoebic encephalitis, a rare but frequently fatal infection of the central nervous system.
Ruqaiyyah Siddiqui +3 more
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