Results 61 to 70 of about 1,079 (146)

Serum Antibodies toBalamuthia mandrillaris,a Free‐Living Amoeba Recently Demonstrated to Cause Granulomatous Amoebic Encephalitis [PDF]

The Journal of Infectious Diseases, 1999
Free-living amoebae cause three well-defined disease entities: a rapidly fatal primary meningoencephalitis, a chronic granulomatous amoebic encephalitis (GAE), and a chronic amoebic keratitis. GAE occurs in immunocompromised persons. Recently, another type of free-living amoeba, Balamuthia mandrillaris, has been shown to cause GAE.
Huang, Z., Ferrante, A., Carter, R.
openaire   +3 more sources

Acanthamoeba castellanii–Mediated Reduction of Interleukin‐1β Secretion and Its Association With Macrophage Autophagy

Scientifica, Volume 2025, Issue 1, 2025.
Noncanonical autophagy including unconventional protein secretion has been extensively studied. Our work focused on a leaderless IL‐1β protein secretion from human macrophage in response to Acanthamoeba castellanii components, Acanthamoeba culture supernatant (CS) and cell lysate (CL), as well as its association with macrophage autophagy.
Rachasak Boonhok, Wilaiwan Senghoi, Suthinee Sangkanu, Chooi Ling Lim, Matsayapan Pudla, Maria de Lourdes Pereira, Polrat Wilairatana, Tooba Mahboob, Md. Atiar Rahman, Pongsak Utaisincharoen, Poonsit Hiransai, Veeranoot Nissapatorn, Simone Carradori   +12 more
wiley   +1 more source

Amebicidal and Antiadhesion Activities of Knema retusa Extract Against Acanthamoeba triangularis T4 Genotype on Contact Lenses and Modeling Simulation of Its Main Compound, E2N, Against Acanthamoeba Beta‐Tubulin

Scientifica, Volume 2025, Issue 1, 2025.
Medicinal plants have been used as alternative agents for the treatment of infections. This study aimed to investigate bioactivities of medicinal plant extracts including Knema retusa extract (Kre) against Acanthamoeba triangularis T4 in vitro and in silico. Anti‐Acanthamoeba activities of 44 extracts from 5 plant species were determined.
Watcharapong Mitsuwan, Imran Sama-ae, Suthinee Sangkanu, Dhrubo Ahmed Khan, Partha Biswas, Md. Nazmul Hasan, Julalak Chuprom, Tajudeen O. Jimoh, Christophe Wiart, Masyitah Binti Zulkipli, Nor Hayati Abdullah, Maria de Lourdes Pereira, Sonia M. Rodrigues Oliveira, Shanmuga Sundar Saravanabhavan, Polrat Wilairatana, Tooba Mahboob, Veeranoot Nissapatorn, Sukhamoy Gorai   +17 more
wiley   +1 more source

Granulomatous Amoebic Encephalitis Caused by Acanthamoeba Amoebae of Genotype T2 in a Human Immunodeficiency Virus-Negative Patient [PDF]

Journal of Clinical Microbiology, 2008
ABSTRACT Acanthamoeba amoebae of genotype T2 were identified as the causative agent of Acanthamoeba skin lesions and granulomatous amoebic encephalitis (GAE) in a human immunodeficiency virus-negative patient with underlying tuberculosis.
Julia, Walochnik, Alexander, Aichelburg, Ojan, Assadian, Andrea, Steuer, Govinda, Visvesvara, Norbert, Vetter, Horst, Aspöck   +6 more
openaire   +2 more sources

Amoebicidal activity of cationic carbosilane dendrons derived with 4-phenylbutyric acid against Acanthamoeba griffini and Acanthamoeba polyphaga trophozoites and cysts

Scientific Reports, 2022
Amoebae from the genus Acanthamoeba are important pathogens responsible for severe illnesses in humans such as Acanthamoeba keratitis and granulomatous amoebic encephalitis. In the last few decades, AK diagnoses have steadily increased.
P. López-Barona, C. Verdú-Expósito, T. Martín-Pérez, N. Gómez-Casanova, T. Lozano-Cruz, P. Ortega, R. Gómez, J. Pérez-Serrano, I. Heredero-Bermejo   +8 more
doaj   +1 more source

Modelling dynamics between free‐living amoebae and bacteria

Environmental Microbiology, Volume 26, Issue 5, May 2024.
This review scrutinizes mathematical models designed to simulate the interactions between free‐living amoebae and bacteria. Identified gaps encompass (1) the necessity to tackle complexities such as spatial heterogeneity and population diversity; and (2) the essential understanding of the system.
Marwa Ali, Christopher A. Rice, Andrew W. Byrne, Philip E. Paré, Wendy Beauvais   +4 more
wiley   +1 more source

Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris.

Neurologia medico-chirurgica, 2013
A 51-year-old immunocompetent Japanese woman presented with a rare case of granulomatous amoebic encephalitis (GAE) caused by Balamuthia mandrillaris. She was brought to our hospital with epilepsy. Magnetic resonance imaging of the brain revealed a homogeneously enhanced solitary mass in the left frontal lobe.
Kouji, Yamasaki, Tetsuaki, Sugimoto, Munetomo, Futami, Takuzo, Moriyama, Hisao, Uehara, Hideo, Takeshima, Sayaka, Moriguchi, Kousuke, Marutsuka, Yujiro, Asada   +8 more
openaire   +1 more source

Fatal Balamuthia mandrillaris Encephalitis

Case Reports in Infectious Diseases, 2019
Balamuthia mandrillaris is a rare cause of granulomatous meningoencephalitis associated with high mortality. We report a 69-year-old Caucasian female who presented with a 3-day history of worsening confusion and difficulty with speech.
Binoy Yohannan, Mark Feldman
doaj   +1 more source

Occurrence of small free-living amoebae from natural water resources

Environment Conservation Journal, 2009
Small  free-living amoebae are also  called  as amphizoic amoebae,  because of their capability to exist both  as free-living  as well  as opportunistically  pathogenic.
Tabrez Ahmad, Newton Paul, A. K. Sharma
doaj   +1 more source

Glucose metabolism in the pathogenic free‐living amoebae: Tempting targets for treatment development

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Enzymes involved in glucose metabolism may be promising therapeutic targets for drug development against the pathogenic free‐living amoebae. Details about the enzyme sequence and structural properties make a compelling case for designing small molecule inhibitors that are specific to the amoebae and would not affect the host enzyme.AbstractPathogenic ...
Jillian E. Milanes, Samuel Kwain, Allyson Drawdy, Laura Dodson, Matthew T. Monaghan, Christopher A. Rice, Brian N. Dominy, Daniel C. Whitehead, James C. Morris   +8 more
wiley   +1 more source