Results 61 to 70 of about 1,377 (200)

In vitro anti‐Trichomonas gallinae effects of Ziziphus vulgaris L. and Camellia sinensis (L.) Kuntze extracts

Veterinary Medicine and Science, Volume 10, Issue 3, May 2024.
Graphical Abstract: Ziziphus vulgaris L. (jujube) and Camellia sinensis (L.) Kuntze extracts have anti‐Trichomonas gallinae effects and could be used as potent natural anti‐Trichomonas gallinae agents. In addition, metronidazole, C. sinensis and Z. vulgaris extracts equally prevent the growth of T. gallinae trophozoites in the culture.
Behnam Rahimi, Farnaz Malekifard, Bijan Esmaeilnejad   +2 more
wiley   +1 more source

In vitro amoebicidal activities of Teucrium polium and T. chamaedrys on Acanthamoeba castellanii trophozoites and cysts

, 2011
Amoebic keratitis is difficult to treat without total efficacy in some patients because of cysts, which are less susceptible than trophozoites to the usual treatments.
Serpil Degerli, Berk, Seyda, Tepe, Bektas, Degerli, Serpil, Erdogan Malatyali, Seyda Berk, Bektas Tepe, Malatyali, Erdogan   +7 more
core   +1 more source

Activity of Silver Nitrate for Treatment of Amoebic Keratitis [PDF]

Brazilian Archives of Biology and Technology
Silver nitrate is an inorganic salt that is active against a wide range of microorganisms, mainly bacteria and fungi. The emergence of antibiotics and new medications led to the abandonment of silver nitrate by modern medicine, however microbial ...
Igor Rodrigues Cardoso, Daniel Ernesto Rodríguez Fernández, Helena Keiko Toma   +2 more
doaj   +1 more source

Glucose metabolism in the pathogenic free‐living amoebae: Tempting targets for treatment development

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Enzymes involved in glucose metabolism may be promising therapeutic targets for drug development against the pathogenic free‐living amoebae. Details about the enzyme sequence and structural properties make a compelling case for designing small molecule inhibitors that are specific to the amoebae and would not affect the host enzyme.AbstractPathogenic ...
Jillian E. Milanes, Samuel Kwain, Allyson Drawdy, Laura Dodson, Matthew T. Monaghan, Christopher A. Rice, Brian N. Dominy, Daniel C. Whitehead, James C. Morris   +8 more
wiley   +1 more source

Modelling amoebic brain infection caused by Balamuthia mandrillaris using a human cerebral organoid.

PLoS Neglected Tropical Diseases
The lack of disease models adequately resembling human tissue has hindered our understanding of amoebic brain infection. Three-dimensional structured organoids provide a microenvironment similar to human tissue.
Nongnat Tongkrajang, Porntida Kobpornchai, Pratima Dubey, Urai Chaisri, Kasem Kulkeaw   +4 more
doaj   +1 more source

Design and synthesis of imidazo[1,2‐a]pyridine‐chalcone conjugates as antikinetoplastid agents

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Imidazo[1,2‐a]pyridine‐chalcone conjugates with antikinetoplastid activity.AbstractA library of imidazo[1,2‐a]pyridine‐appended chalcones were synthesized and characterized using 1H NMR, 13C NMR and HRMS. The synthesized analogues were screened for their antikinetoplastid activity against Trypanosoma cruzi, Trypanosoma brucei brucei, Trypanosoma brucei
Devesh S. Agarwal, Richard M. Beteck, Kayhan Ilbeigi, Guy Caljon, Lesetja J. Legoabe   +4 more
wiley   +1 more source

Protamine as a potential amoebicidal agent for contact lens disinfection

, 2013
PURPOSE: To evaluate the amoebicidal efficacy of protamine with polyhexamethylene biguanide (PHMB) and ethylenediamine tetraacetic acid (EDTA). METHODS: The International Organization for Standardization 14729:2001 procedure was modified to test ...
Vijay, AK ; https://orcid.org/, Bandara, BM, Willcox, MD, Zhu, H   +3 more
core   +1 more source

Cobalt nanoparticles as novel nanotherapeutics against Acanthamoeba castellanii

Parasites & Vectors, 2019
Background Species of Acanthamoeba are facultative pathogens which can cause sight threatening Acanthamoeba keratitis and a rare but deadly brain infection, granulomatous amoebic encephalitis.
Ayaz Anwar, Arshid Numan, Ruqaiyyah Siddiqui, Mohammad Khalid, Naveed Ahmed Khan   +4 more
doaj   +1 more source

Exploring Medicinal Plants for Antimicrobial Activity and Synergistic Effects With Doxycycline Against Bacterial Species

The Scientific World Journal, Volume 2024, Issue 1, 2024.
Medicinal plants are rich sources of bioactive compounds with diverse pharmacological properties, including antimicrobial activities. This study aimed to assess the antibiofilm potential of methanol and ethanol extracts from nine selected medicinal plants, as well as their synergistic effects with doxycycline against Bacillus strains.
Joel Frank Kenmeni, Ibrahim Sifi, Borel Ndezo Bisso, Prudence Ngalula Kayoka-Kabongo, Ulrich Joël Tsopmene, Jean Paul Dzoyem, José Agustín Tapia Hernández   +6 more
wiley   +1 more source

Quercetin as a Promising Antiprotozoan Phytochemical: Current Knowledge and Future Research Avenues

BioMed Research International, Volume 2024, Issue 1, 2024.
Despite tremendous advances in the prevention and treatment of infectious diseases, only few antiparasitic drugs have been developed to date. Protozoan infections such as malaria, leishmaniasis, and trypanosomiasis continue to exact an enormous toll on public health worldwide, underscoring the need to discover novel antiprotozoan drugs. Recently, there
Hamed Memariani, Mojtaba Memariani, Abdolmajid Ghasemian, Rahul Shivahare   +3 more
wiley   +1 more source