In vitro validation of the amoebicidal activity of commercial eye drops as second activity [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2021 The validation of anti-Acanthamoeba activity of commercial eye drops has gained a great interest recently and a growing number of commercials eye drop were evaluated for their aptitude to inhibit Acanthamoeba as a second pharmacological effect.
Olfa Chiboub +6 more
doaj +7 more sources
The Amoebicidal Activity of Diferrocenyl Derivatives: A Significant Dependence on the Electronic Environment [PDF]
Molecules, 2023 Amoebiasis is the second leading cause of death worldwide associated with parasitic disease and is becoming a critical health problem in low-income countries, urging new treatment alternatives.
Yanis Toledano-Magaña +6 more
doaj +5 more sources
New Protein-Coated Silver Nanoparticles: Characterization, Antitumor and Amoebicidal Activity, Antiproliferative Selectivity, Genotoxicity, and Biocompatibility Evaluation [PDF]
Pharmaceutics, 2021 Nanomaterials quickly evolve to produce safe and effective biomedical alternatives, mainly silver nanoparticles (AgNPs). The AgNPs’ antibacterial, antiviral, and antitumor properties convert them into a recurrent scaffold to produce new treatment options.
Lucía Margarita Valenzuela-Salas +12 more
doaj +5 more sources
Potential Amoebicidal Activity of Hydrazone Derivatives: Synthesis, Characterization, Electrochemical Behavior, Theoretical Study and Evaluation of the Biological Activity [PDF]
Molecules, 2015 Four new hydrazones were synthesized by the condensation of the selected hydrazine and the appropriate nitrobenzaldehyde. A complete characterization was done employing 1H- and 13C-NMR, electrochemical techniques and theoretical studies.
Yanis Toledano-Magaña +9 more
doaj +5 more sources
Amoebicidal activity of cationic carbosilane dendrons derived with 4-phenylbutyric acid against Acanthamoeba griffini and Acanthamoeba polyphaga trophozoites and cysts [PDF]
Scientific Reports, 2022 Amoebae from the genus Acanthamoeba are important pathogens responsible for severe illnesses in humans such as Acanthamoeba keratitis and granulomatous amoebic encephalitis. In the last few decades, AK diagnoses have steadily increased.
P. López-Barona +8 more
doaj +3 more sources
Amoebicidal Activity of Poly-Epsilon-Lysine Functionalized Hydrogels. [PDF]
Invest Ophthalmol Vis Sci, 2022 To determine the amoebicidal activity of functionalized poly-epsilon-lysine hydrogels (pɛK+) against Acanthamoeba castellanii.A. castellanii trophozoites and cysts were grown in the presence of pɛK solution (0-2.17 mM), pɛK or pɛK+ hydrogels, or commercial hydrogel contact lens (CL) for 24 hours or 7 days in PBS or Peptone-Yeast-Glucose (PYG) media ...
Kennedy SM +7 more
europepmc +5 more sources
Iris setosa Pall. ex Link Extract Reveals Amoebicidal Activity against Acanthamoeba castellanii and Acanthamoeba polyphaga with Low Toxicity to Human Corneal Cells [PDF]
MicroorganismsAcanthamoeba keratitis (AK) is a sight-threatening and difficult-to-treat ocular infection. The significant side effects of current AK treatments highlight the urgent need to develop a safe and effective AK medication.
Hương Giang Lê +7 more
doaj +3 more sources
Nitroxoline evidence amoebicidal activity against Acanthamoeba castellanii through DNA damage and the stress response pathways [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceAcanthamoeba castellanii is a widespread unicellular eukaryote found in diverse environments, including tap water, soil, and swimming pools. It is responsible for severe infections, such as Acanthamoeba keratitis and granulomatous amebic encephalitis ...
Lijun Chen +5 more
doaj +3 more sources
Amoebicidal Activity of Caffeine and Maslinic Acid by the Induction of Programmed Cell Death in Acanthamoeba. [PDF]
Antimicrob Agents Chemother, 2017 ABSTRACT Free-living amoebae of the genus Acanthamoeba are the causal agents of a sight-threatening ulceration of the cornea called Acanthamoeba keratitis, as well as the rare but usually fatal disease granulomatous amoebic encephalitis.
Martín-Navarro CM +10 more
europepmc +6 more sources
The amoebicidal activity of Chaerophyllum macropodum extract on Acanthamoeba genotype T4 in vitro
مجله علمی دانشگاه علوم پزشکی کردستان, 2022 Background and Aim: Acanthamoeba is an opportunistic pathogen that may cause fatal granulomatous encephalitis and ocular keratitis in humans and animals.
Tooran Nayeri +5 more
doaj +3 more sources