Recombinant protein expression in Acanthamoeba castellanii [PDF]
Frontiers in Bioengineering and BiotechnologyThe ongoing quest to improve protein production efficiency, quality, and versatility fuels the exploration of novel expression systems. In this research, we explored the potential of the axenically culturable Acanthamoeba as an alternative for producing ...
Pooja Salunke +4 more
doaj +4 more sources
Disseminated Acanthamoeba castellanii infection in a patient with AIDS: a case report and literature review [PDF]
Frontiers in MedicineBackgroundAcanthamoeba castellanii infection is a rare condition primarily occurring in immunocompromised patients with extremely high mortality. Currently, there is no standard treatment for this condition, and successful treatment reports are scarce ...
Zhongwei Zhang +2 more
exaly +4 more sources
Commensals Serve as Natural Barriers to Mammalian Cells during Acanthamoeba castellanii Invasion
Microbiology Spectrum, 2021 Acanthamoeba castellanii is a free-living, pathogenic ameba found in the soil and water. It invades the body through ulcerated skin, the nasal passages, and eyes and can cause blinding keratitis and granulomatous encephalitis.
Yu-Jen Wang +2 more
exaly +3 more sources
Inhibitory Effect of a Novel Ophthalmic Solution on Acanthamoeba castellanii Adhesion and Biofilm Formation on Human Corneal Epithelium [PDF]
LifeBackground/Objectives: Acanthamoeba keratitis (AK) is a rare but sight-threatening corneal infection, often associated with contact lens wear and resistant to conventional therapies.
Francesco D’Oria +8 more
doaj +2 more sources
The Activity of Polyhomoarginine against Acanthamoeba castellanii
Biology, 2022 Arginine-rich peptides can have broad-spectrum anti-bacterial and anti-fungal activities. Polyhomoarginine consists of highly cationic residues which can act on the negatively charged microbial cell membranes.
Hari Kumar Peguda +4 more
doaj +4 more sources
Acanthamoeba castellanii–Mediated Reduction of Interleukin-1β Secretion and Its Association With Macrophage Autophagy [PDF]
ScientificaNoncanonical autophagy including unconventional protein secretion has been extensively studied. Our work focused on a leaderless IL-1β protein secretion from human macrophage in response to Acanthamoeba castellanii components, Acanthamoeba culture ...
Rachasak Boonhok +11 more
doaj +2 more sources
Unveiling the molecular architecture of the mitochondrial respiratory chain of Acanthamoeba castellanii [PDF]
Microbial CellAcanthamoeba castellanii is a ubiquitous free-living amoeba that can cause severe infections in humans. Unlike most other organisms, A. castellanii possesses a “complete” mitochondrial respiratory chain, meaning it contains several additional enzymes ...
Christian Q. Scheckhuber +2 more
doaj +2 more sources
The fate of artificial transgenes in Acanthamoeba castellanii. [PDF]
BMC GenomicsAbstract In this study, artificial transformation experiments were performed to investigate how the A. castellanii genome responds to foreign DNA presented in both circular and linear plasmid form.
Colp MJ +3 more
europepmc +4 more sources
Acanthamoeba castellanii STAT protein. [PDF]
PLoS ONE, 2014 STAT (signal transducers and activators of transcription) proteins are one of the important mediators of phosphotyrosine-regulated signaling in metazoan cells.
Anna Kicinska +2 more
doaj +4 more sources
Encystment and Excystment Processes in Acanthamoeba castellanii: An Emphasis on Cellulose Involvement [PDF]
PathogensThe free-living amoeba Acanthamoeba castellanii is a unicellular eukaryote distributed in a wide range of soil or aquatic environments, either natural or human-made, such as rivers, lakes, drinking water, or swimming pools.
Mathew Choaji +4 more
doaj +2 more sources