Results 31 to 40 of about 3,715 (174)

Targeting Acanthamoeba proteins interaction with flavonoids of Propolis extract by in vitro and in silico studies for promising therapeutic effects [version 3; peer review: 2 approved]

F1000Research, 2023
Background: Propolis is a natural resinous mixture produced by bees. It provides beneficial effects on human health in the treatment/management of many diseases.
Tooba Mahboob, Polrat Wilairatana, Mohammed Rahmatullah, Karma G. Dolma, Maria de Lourdes Pereira, Christophe Wiart, Madhu Gupta, Chea Sin, Tajudeen O. Jimoh, Sónia M.R. Oliveira, Alok K. Paul, Najme Sadat Abtahi, Watcharapong Mitsuwan, Rachasak Boonhok, Roghayeh Norouzi, Julalak Chuprom, Suthinee Sangkanu, Veeranoot Nissapatorn, Abolghasem Siyadatpanah, Imran Sama-ae, Sirirat Surinkaew   +20 more
doaj   +1 more source

Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis

Data in Brief, 2018
The recombinant TvCP4 prepro region (ppTvCP4r) acts as an exogenous inhibitor of cathepsin L-like CPs from Trichomonas vaginalis (Cárdenas-Guerra et al., 2015 [1]). Here, we present the dataset of the trichomonad ppTvCP4r inhibitory effect against the CP
Rosa E. Cárdenas-Guerra, Moisés Martínez-Castillo, Jaime Ortega-López, Mineko Shibayama, Rossana Arroyo   +4 more
doaj   +1 more source

Infection of Acanthamoeba castellanii by Chlamydia pneumoniae [PDF]

Applied and Environmental Microbiology, 1997
Chlamydia pneumoniae is an intracellular respiratory pathogen, which, similar to Legionella, might have developed mechanisms to escape the intracellular bactericidal activity of both human host cells and amoeba. We therefore investigated the intracellular growth and survival of C.
A, Essig, M, Heinemann, U, Simnacher, R, Marre   +3 more
openaire   +2 more sources

The Effect of Plasma Activated Water on Acanthamoeba castellanii

Journal of Ardabil University of Medical Sciences, 2021
Background & Objectives: Cold Plasma is an emerging non-thermal, chemical-free, environmentally friendly disinfection technology. Plasma-activated water has received considerable attention from researchers in recent years.
Mojtaba Darvishi, Somayeh Bahrami, Mehdi Zarei, Mohammad Sabaeian   +3 more
doaj  

Targeting Acanthamoeba proteins interaction with flavonoids of Propolis extract by in vitro and in silico studies for promising therapeutic effects [version 2; peer review: 2 approved]

F1000Research, 2023
Background: Propolis is a natural resinous mixture produced by bees. It provides beneficial effects on human health in the treatment/management of many diseases.
Tooba Mahboob, Polrat Wilairatana, Mohammed Rahmatullah, Karma G. Dolma, Maria de Lourdes Pereira, Christophe Wiart, Madhu Gupta, Chea Sin, Tajudeen O. Jimoh, Sónia M.R. Oliveira, Alok K. Paul, Najme Sadat Abtahi, Watcharapong Mitsuwan, Rachasak Boonhok, Roghayeh Norouzi, Julalak Chuprom, Suthinee Sangkanu, Veeranoot Nissapatorn, Abolghasem Siyadatpanah, Imran Sama-ae, Sirirat Surinkaew   +20 more
doaj   +1 more source

The effect of the disulfideisomerase domain containing protein in the defense against polyhexamethylene biguanide of highly tolerant Acanthamoeba at the trophozoite stage

International Journal for Parasitology: Drugs and Drug Resistance, 2016
Acanthamoeba castellanii is a free-living protozoan pathogen capable of causing a blinding keratitis and fatal granulomatous encephalitis. Current treatment generally involves an hourly application of polyhexamethylene biguanide (PHMB) over a period of ...
Fu-Chin Huang, Tao-Shen Liu, Sung-Chou Li, Min-Hsiu Shih, Jyh-Wei Shin, Wei-Chen Lin   +5 more
doaj   +1 more source

Detection of Acanthamoeba from Acanthamoeba Keratitis Mouse Model Using Acanthamoeba-Specific Antibodies

Microorganisms, 2022
Although the prevalence of Acanthamoeba keratitis (AK) is rare, its incidence in contact lens wearers has increased. Acanthamoeba infections can lead to the loss of vision if the diagnosis and treatment are delayed.
Min-Jeong Kim, A-Jeong Ham, A-Young Park, Hae-Jin Sohn, Ho-Joon Shin, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon   +7 more
doaj   +1 more source

Antiamoebic Properties of Ceftriaxone and Zinc-Oxide–Cyclodextrin-Conjugated Ceftriaxone

Antibiotics, 2022
Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent.
Zinb Makhlouf, Noor Akbar, Naveed Ahmed Khan, Muhammad Raza Shah, Ahmad M. Alharbi, Hasan Alfahemi, Ruqaiyyah Siddiqui   +6 more
doaj   +1 more source

Stable transfection of Acanthamoeba castellanii

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005
A simple method for stable transfection of Acanthamoeba castellanii using plasmids which confer resistance to neomycin G418 is described. Expression of neomycin phosphotransferase is driven by the Acanthamoeba TBP gene promoter, and can be monitored by cell growth in the presence of neomycin G418 or by Western blot analysis.
Peng, Zhihua, Omaruddin, Romaica, Bateman, Erik   +2 more
openaire   +2 more sources

Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba

Scientific Reports, 2017
The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sight-threatening infection of the eye and the almost universally fatal granulomatous amoebic encephalitis. More effective treatments are required.
Scott Thomson, Christopher A. Rice, Tong Zhang, RuAngelie Edrada-Ebel, Fiona L. Henriquez, Craig W. Roberts   +5 more
doaj   +1 more source