Results 51 to 60 of about 3,715 (174)

In Vitro Stability of the Biological Activity of Voriconazole against Acanthamoeba castellanii

Parasitologia, 2023
Acanthamoeba keratitis (AK) is a rare cornea disease caused by species of the Acanthamoeba genus. The antifungal voriconazole blocks the ergosterol synthesis in the protozoan membrane and is active against the cysts and trophozoites of Acanthamoeba spp ...
Barbara Czerniak Rodrigues, Maria Luiza Carneiro Büchele, Carolina de Jesus de Camargo, Fabíola Branco Filippin-Monteiro, Karin Silva Caumo   +4 more
doaj   +1 more source

Making fish oils in plants: from alpha to omega

New Phytologist, Volume 251, Issue 3, Page 1013-1018, August 2026.
Schematic representation of the biosynthetic pathway for the synthesis of omega‐3 long‐chain polyunsaturated fatty acids. The sequential transgene‐encoded activities required to convert endogenous fatty acids to the longer chain polyunsaturated forms of eicosapentaenoic acid and docosahexaenoic acid are shown in red.
Johnathan A. Napier
wiley   +1 more source

Quantitative proteomic analysis and functional characterization of Acanthamoeba castellanii exosome-like vesicles

Parasites & Vectors, 2019
Background Pathogenic protozoans use extracellular vesicles (EVs) for intercellular communication and host manipulation. Acanthamoeba castellanii is a free-living protozoan that may cause severe keratitis and fatal granulomatous encephalitis.
Wei-Chen Lin, Chia-Yun Tsai, Jian-Ming Huang, Shang-Rung Wu, Lichieh Julie Chu, Kuo-Yang Huang   +5 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, Volume 600, Issue 10, Page 1491-1518, May 2026.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Investigation of In Vitro Amoebicidal Activities of Trachystemon orientalis on Acanthamoeba castellanii Cysts and Trophozoites

Van Tıp Dergisi, 2019
INTRODUCTION: Acanthamoeba species cause important diseases such as Acanthamoeba keratitis, granulomatous amoebic encephalitis and cutaneous acanthamoebiasis.
Bülent Kaynak, Zeynep Kolören, Ülkü Karaman   +2 more
doaj   +1 more source

Molecular Mimicry Between Epstein‐Barr Virus and Human Herpesvirus‐6 Proteins and Central Nervous System Proteins: Implications for T and B Cell Immunogenicity in an In Silico Study

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background The Epstein‐Barr virus (EBV) and human herpesvirus 6 (HHV‐6) are frequently linked to neuropsychiatric illnesses such as multiple sclerosis, depression, and chronic fatigue syndrome/myalgic encephalomyelitis. These viruses may induce autoimmune reactions by molecular mimicry, leading to damage to self‐epitopes in the central nervous
Abbas F. Almulla, Muslimbek G. Normatov, Thitiporn Supasitthumrong, Michael Maes   +3 more
wiley   +1 more source

Impact of Fire and Heat Stress on Soil Microorganisms: A Review of Community Changes, Molecular Responses and Plant‐Beneficial Roles

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
This work reviewed the direct and indirect effects of fires on microbial communities and the resilience strategies microbes use to withstand high temperatures . ABSTRACT Fire, whether occurring on the surface or underground, significantly influences soil microbial dynamics by reshaping community composition, functional diversity and overall soil and ...
Ma. del Carmen Orozco‐Mosqueda, Aurora Flores‐Piña, Ajay Kumar, Fannie I. Parra‐Cota, Sergio de los Santos‐Villalobos, Debasis Mitra, Olubukola Oluranti Babalola, Gustavo Santoyo   +7 more
wiley   +1 more source

Phytochemical and Biological Evaluation of Leaves, Stems, and Roots of Schinus weinmanniifolia Mart. Ex Engl.

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Ethanolic extracts from leaves, stems, and roots of Schinus weinmanniifolia Mart. ex Engl. were evaluated for phytochemical composition and biological activities. The extracts exhibited antioxidant, photoprotective, and antimicrobial activity, without hemolytic effects or cytotoxicity at active concentrations. Syringic acid, epicatechin, and rutin were
João Andrade, Adriana Araújo de Almeida‐Apolonio, Fabiana Gomes da Silva Dantas, José Irlan da Silva Santos, Andréia Sangalli, Melyssa Negri, Deisiany Gomes Ferreira, Claudia Andrea Lima Cardoso, Thiago Luis Aguayo de Castro, Aline dos Santos Garcia Gomes, Rhagner Bonono, Liliana Fernandes, Maria Elisa Rodrigues, Mariana Contente Rangel Henriques, Kelly Mari Pires de Oliveira   +14 more
wiley   +1 more source

Tigecycline inhibits proliferation of Acanthamoeba castellanii

Parasitology Research, 2015
Acanthamoeba is an opportunistic protozoan parasite responsible for different diseases in humans, such as granulomatous amoebic encephalitis and amoebic keratitis. Tigecycline, a third-generation tetracycline antibiotic, has potential activity to treat most of the antibiotic resistant bacterial infections. The effects of tigecycline in eukaryotic cells
Bijay Kumar Jha, Incheol Seo, Hyun-Hee Kong, Seong-Il Suh, Min-Ho Suh, Won-Ki Baek   +5 more
openaire   +3 more sources

What We Can Do in Infectious Keratitis, Except for Conventional Antimicrobial‐Based Therapies: Major Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Infectious keratitis (IK) is classified as a critical ophthalmic emergency, with the potential to result in vision‐impairing complications. The treatment approach involves the use of pharmacological antimicrobial agents in combination with surgical interventions.
Kasra Cheraqpour
wiley   +1 more source