Journal of Parasitology Research, 2023 Acanthamoeba griffini is known to cause amoebic keratitis (AK); its main causes are inadequate hygiene when contact lenses are handled and/or its prolonged use at night, as well as the use of contact lenses during underwater activities.
Manuel Enrique Ávila-Blanco +5 more
doaj +2 more sources
The Anti-Amoebic Activity of a Peptidomimetic against Acanthamoeba castellanii
Microorganisms, 2022 Acanthamoeba is a free-living protozoan known to cause keratitis most commonly, especially among contact lens wearers. Treatment of Acanthamoeba keratitis is challenging as Acanthamoeba can encyst from the active form, a trophozoite, into a hibernating ...
Hari Kumar Peguda +5 more
doaj +3 more sources
Anti-Acanthamoeba Activity of Brominated Sesquiterpenes from Laurencia johnstonii [PDF]
Marine Drugs, 2018 Focused on our interest to develop novel antiparasistic agents, the present study was aimed to evaluate the biological activity of an extract of Laurencia johnstonii collected in Baja California Sur, Mexico, against an Acantamoeba castellanii Neff strain.
Sara García-Davis +7 more
doaj +3 more sources
Experimental and Theoretical Evidence on the Amoebicidal Activity of Synthesized tRNA-Palmitic Acid Esters [PDF]
Iranian Journal of Chemistry & Chemical EngineeringSynthesis of tRNA-palmitic acid esters was carried out in dimethyl sulfoxide (DMSO) and tert-butanol, %20 and %80 (v/v), respectively, for 24h at 55oC.
Aysun Aksu +5 more
doaj +2 more sources
Amoebicidal Effect of COVID Box Molecules against Acanthamoeba: A Study of Cell Death
PharmaceuticalsAcanthamoeba spp. can cause a sight threatening disease. At present, the current treatments used to treat Acanthamoeba spp. Infections, such as biguanide-based antimicrobials, remain inefficacious, with the appearance of resistant forms and high ...
Ines Sifaoui +5 more
doaj +2 more sources
Inhibitory Effect of a Novel Ophthalmic Solution on Acanthamoeba castellanii Adhesion and Biofilm Formation on Human Corneal Epithelium [PDF]
LifeBackground/Objectives: Acanthamoeba keratitis (AK) is a rare but sight-threatening corneal infection, often associated with contact lens wear and resistant to conventional therapies.
Francesco D’Oria +8 more
doaj +2 more sources
The amoebicidal activity of Chaerophyllum macropodum extract on Acanthamoeba genotype T4 in vitro
مجله علمی دانشگاه علوم پزشکی کردستان, 2022 Background and Aim: Acanthamoeba is an opportunistic pathogen that may cause fatal granulomatous encephalitis and ocular keratitis in humans and animals.
Tooran Nayeri +5 more
doaj +2 more sources
Evaluating the amoeba thioredoxin reductase selenoprotein as potential drug target for treatment of Acanthamoeba infections [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceThe genus Acanthamoeba comprises facultative pathogens, causing Acanthamoeba keratitis (AK) and granulomatous amoebic encephalitis (GAE). In both diseases, treatment options are limited, and drug development is challenging.
Alvie Loufouma-Mbouaka +6 more
doaj +2 more sources
Development of a Novel Ex-vivo 3D Model to Screen Amoebicidal Activity on Infected Tissue. [PDF]
Sci Rep, 2019 Amoebiasis is a parasitic disease that causes thousands of deaths every year, its adverse effects and resistance to conventional treatments have led to the search of new treatment options, as well as the development of novel screening methods.
Guzmán-Delgado NE +8 more
europepmc +2 more sources
In vitro amoebicidal activity of immune cells [PDF]
Infection and Immunity, 1982 The amoebicidal activity of peripheral blood lymphocytes and spleen and peritoneal cells from hamsters vaccinated against or protected from hepatic amoebiasis and from those with hepatic amoebiasis was investigated. Peripheral blood lymphocytes and peritoneal and spleen cells from vaccinated or protected animals can kill trophozoites of Entamoeba ...
E, Ghadirian, E, Meerovitch
openaire +2 more sources