Amoebicidal activity of curcumin on Entamoeba histolytica trophozoites
Journal of Pharmacy and Pharmacology, 2018 Abstract Objectives This study was undertaken to investigate the amoebicidal potential of curcumin on Entamoeba histolytica, as well as its synergistic effect with metronidazole. Methods Entamoeba histolytica trophozoites were exposed
Itzia Azucena Rangel-Castañeda +8 more
openaire +3 more sources
Expanding the antiprotozoal activity and the mechanism of action of n-butyl and iso-butyl ester of quinoxaline-1,4-di-N-oxide derivatives against Giardia lamblia, Trichomonas vaginalis, and Entamoeba histolytica. An in vitro and in silico approach [PDF]
Journal of Enzyme Inhibition and Medicinal ChemistryIn this study, n-butyl and iso-butyl quinoxaline-7-carboxylate-1,4-di-N-oxide derivatives were evaluated in vitro against Giardia lamblia (G. lamblia), Trichomonas vaginalis (T. vaginalis), and Entamoeba histolytica (E. histolytica).
Alonzo González-González +13 more
doaj +2 more sources
International Journal for Parasitology: Drugs and Drug ResistanceNaegleria fowleri is a free-living amoeba that causes a rare but almost always fatal brain infection known as primary amoebic meningoencephalitis (PAM). Although amphotericin B (AmB) is considered the primary treatment for PAM, it is often recommended in
Hae-Ahm Lee +4 more
doaj +2 more sources
Amoebicidal Activity of Essential Oil of Dysphania ambrosioides (L.) Mosyakin & Clemants in an Amoebic Liver Abscess Hamster Model. [PDF]
Evid Based Complement Alternat Med, 2014 Amebiasis is a parasitic disease that extends worldwide and is a public health problem in developing countries. Metronidazole is the drug recommended in the treatment of amebiasis, but its contralateral effects and lack of continuity of treatment induce ...
Avila-Blanco ME +4 more
europepmc +2 more sources
Amoebicidal Effect of COVID Box Molecules against Acanthamoeba: A Study of Cell Death [PDF]
PharmaceuticalsAcanthamoeba spp. can cause a sight threatening disease. At present, the current treatments used to treat Acanthamoeba spp. Infections, such as biguanide-based antimicrobials, remain inefficacious, with the appearance of resistant forms and high ...
Ines Sifaoui +5 more
doaj +2 more sources
In Vitro Amoebicidal Activity of Titanium Dioxide/UV-A Combination AgainstAcanthamoeba
Investigative Opthalmology & Visual Science, 2018 To assess the amoebicidal effect of titanium dioxide (TiO2)/UV-A combination against Acanthamoeba sp trophozoites and cysts.The amoebicidal effect of the TiO2/UV-A combination was tested on trophozoites and cysts of clinical isolates of Acanthamoeba hatchetti and Acanthamoeba sp genotype T4, obtained from two severe cases of ulcerative keratitis ...
Gabrielle, Gomart +6 more
openaire +3 more sources
Amoebicidal activity of phytosynthesized silver nanoparticles and theirin vitrocytotoxicity to human cells [PDF]
FEMS Microbiology Letters, 2013 Acanthamoeba causes infections in humans and other animals and it is important to develop treatment therapies. Jatropha curcas, Jatropha gossypifolia and Euphorbia milii plant extracts synthesized stable silver nanoparticles (AgNPs) that were relatively stable. Amoebicidal activity of J. gossypifolia, J. curcas and E.
Hemant P, Borase +4 more
openaire +3 more sources
Inhibitory Effect of a Novel Ophthalmic Solution on Acanthamoeba castellanii Adhesion and Biofilm Formation on Human Corneal Epithelium [PDF]
LifeBackground/Objectives: Acanthamoeba keratitis (AK) is a rare but sight-threatening corneal infection, often associated with contact lens wear and resistant to conventional therapies.
Francesco D’Oria +8 more
doaj +2 more sources
In vitro amoebicidal and antioxidant activity of Helianthemum ledifolium (L.) Mill. varieties
Biological Diversity and ConservationPurpose: Acanthamoeba spp. are opportunistic protozoa causing Acanthamoeba keratitis (AK), an ocular infection frequently associated with contact lens use. Given the limitations and adverse effects of current treatments, this study aimed to discover natural, safe, and cost-effective therapeutic alternatives. Specifically, the purpose was to investigate
Ayşe Baldemir Kılıç +6 more
openaire +2 more sources
Evaluating the amoeba thioredoxin reductase selenoprotein as potential drug target for treatment of Acanthamoeba infections [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceThe genus Acanthamoeba comprises facultative pathogens, causing Acanthamoeba keratitis (AK) and granulomatous amoebic encephalitis (GAE). In both diseases, treatment options are limited, and drug development is challenging.
Alvie Loufouma-Mbouaka +6 more
doaj +2 more sources