Results 41 to 50 of about 186,704 (266)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Nano Biomedicine and EngineeringThe effect of the thermal treatment of waste oyster (Crassostrea belcheri) shells on different properties was explored. In this preliminary work, the waste oyster shells were collected from Muar River, Malaysia.
S. A. Rosli +6 more
doaj +1 more source
Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage
Molecules, 2019 This study explores the effect of physical aging and/or crystallization on the supersaturation potential and crystallization kinetics of amorphous active pharmaceutical ingredients (APIs).
Khadijah Edueng +5 more
doaj +1 more source
Pharmaceutics, 2023 Four model polymers, representing (i) amorphous homopolymers (Kollidon K30, K30), (ii) amorphous heteropolymers (Kollidon VA64, KVA), (iii) semi-crystalline homopolymers (Parteck MXP, PXP), and (iv) semi-crystalline heteropolymers (Kollicoat IR, KIR ...
Daniel Kramarczyk +5 more
doaj +1 more source
Amorphous-amorphous transitions in granular packings
Nature CommunicationsAbstract Polyamorphs are the amorphous counterparts of the distinct crystalline phases that are found in the phase diagram of a substance. For a given system, polyamorphs have different local structures, resulting in distinct macroscopic properties, making them important for fundamental science and applications.
Houfei Yuan, Walter Kob, Yujie Wang
openaire +2 more sources
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Pharmaceutics, 2020 We have previously reported that heated powder mixtures of ibuprofen (IBU) and high surface area nanocellulose exhibit an enhanced dissolution and solubility of the drug due to IBU amorphization.
Athanasios Mantas +2 more
doaj +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Comment on “First-Order Amorphous-Amorphous Transformation in Silica” [PDF]
Physical Review Letters, 2001 Physical Review ...
openaire +3 more sources