BMC Pharmacology and Toxicology, 2020 Background In developing countries, brand-generic substitution is not based on validated scientific evidence that confirm the therapeutic equivalence of the generic to the originator.
Eva Hobeika +7 more
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Is the standard dose of amoxicillin-clavulanic acid sufficient? [PDF]
, 2014 Background: The pharmacodynamic (PD) efficacy target of amoxicillin is 40% time above the minimal inhibition concentration (40% T > MIC). Recent studies of other antibiotics have shown that PD-efficacy targets are not always reached.
Bruggeman, C +18 more
core +2 more sources
Adverse drug reactions related to amoxicillin alone and in association with clavulanic acid: data from spontaneous reporting in Italy [PDF]
, 2007 OBJECTIVES: To analyse an Italian database of spontaneous reporting of suspected adverse drug reactions in order to compare the safety profile of amoxicillin and amoxicillin/clavulanic acid.
MORETTI, Ugo +8 more
core +2 more sources
High-Dose amoxicillin supported with clavulanic acid as empirical therapy in acute otitis media
Asian Journal of Medical Sciences, 2021 An increase in the daily dose of amoxicillin from 45 mg/kg to 90 mg/kg was introduced in late 2000 to respond to increasing presence of penicillin-resistant Streptococcus pneumoniae (PRSP) in Acute Otitis Media (AOM) and in other respiratory infections ...
Sandeep Lahiry +3 more
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Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
The Scientific World Journal, 2002 The aims of this investigation were to calculate the pharmacokinetic parameters and to identify parameters, based on individual plasma concentration-time curves of amoxicillin and clavulanic acid in cats, that may govern the observed differences in ...
Tom B. Vree +2 more
doaj +1 more source
Structural Variabilities in β-Lactamase (blaA) of Different Biovars of Yersinia enterocolitica: Implications for β-Lactam Antibiotic and β-Lactamase Inhibitor Susceptibilities. [PDF]
PLoS ONE, 2014 Yersiniosis caused by Yersinia enterocolitica has been reported from all continents. The bacterial species is divided into more than fifty serovars and six biovars viz.
Neelja Singhal +3 more
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International Journal of Dentistry, 2015 Background. Treatment of odontogenic infections includes surgical drainage and adjunctive antibiotics. This study was designed to generate efficacy and safety data to support twice daily dosing of amoxicillin/clavulanic acid compared to clindamycin in ...
Archiel Launch Tancawan +8 more
doaj +1 more source
A validated stability-indicating high performance liquid chromatographic assay of amoxicillin [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2000 The purpose of this work is to develop a selective, simple, rapid and accurate liq. chromatog. method for the anal. of amoxicillin and its possible degrdn. products in bulk drug. Amoxicillin and its degrdn.
A. Khedr, I. Darwish
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Pharmacokinetics and Drug Residue in Eggs After Multiple-Day Oral Dosing of Amoxicillin-Clavulanic Acid in Domestic Chickens [PDF]
, 2020 This study examined the pharmacokinetics of orally administered amoxicillin and clavulanic acid tablets (Clavamox, 125 mg/kg PO q12h for 9 doses) in domestic hens and examined both amoxicillin and clavulanic acid concentrations in eggs.
Cox, Sherry K +6 more
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