Results 21 to 30 of about 94,986 (251)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Characterization of the Adaptive Amoxicillin Resistance of Lactobacillus casei Zhang by Proteomic Analysis

Frontiers in Microbiology, 2018
Amoxicillin is one of the most commonly prescribed antibiotics for bacterial infections and gastrointestinal disorders. To investigate the adaptation of Lactobacillus (L.) casei Zhang to amoxicillin stress, an iTRAQ-based comparative proteomic analysis ...
Jicheng Wang, Huiling Guo, Chenxia Cao, Wei Zhao, Lai-Yu Kwok, Heping Zhang, Wenyi Zhang   +6 more
doaj   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

In Vitro Microevolution and Co-Selection Assessment of Amoxicillin and Cefotaxime Impact on Escherichia coli Resistance Development

Antibiotics
The global spread of antimicrobial resistance has become a prominent issue in both veterinary and public health in the 21st century. The extensive use of amoxicillin, a beta-lactam antibiotic, and consequent resistance development are particularly ...
Ádám Kerek, Bence Török, Levente Laczkó, Zoltán Somogyi, Gábor Kardos, Krisztián Bányai, Eszter Kaszab, Krisztina Bali, Ákos Jerzsele   +8 more
doaj   +1 more source

A multifaceted intervention to reduce antibiotic prescribing among CHIldren with acute COugh and respiratory tract infection: the CHICO cluster RCT

Health Technology Assessment, 2023
Background Clinical uncertainty in primary care regarding the prognosis of children with respiratory tract infections contributes to the unnecessary use of antibiotics.
Peter S Blair, Grace J Young, Clare Clement, Padraig Dixon, Penny Seume, Jenny Ingram, Jodi Taylor, Jeremy Horwood, Patricia J Lucas, Christie Cabral, Nick A Francis, Elizabeth Beech, Martin Gulliford, Sam Creavin, Janet A Lane, Scott Bevan, Alastair D Hay   +16 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Green Carbon Dots from Pinecones and Pine Bark for Amoxicillin and Tetracycline Detection: A Circular Economy Approach

Journal of Xenobiotics
Over the years, the abuse of antibiotics has increased, leading to their presence in the environment. Therefore, a sustainable method for detecting these substances is crucial.
Saheed O. Sanni, Ajibola A. Bayode, Hendrik G. Brink, Nils H. Haneklaus, Lin Fu, Jianping Shang, Hua-Jun Shawn Fan   +6 more
doaj   +1 more source

Effect of Iron Oxide Nanoparticles and Amoxicillin on Bacterial Growth in the Presence of Dissolved Organic Carbon

Biomedicines, 2017
The impact of emerging contaminants in the presence of active pharmaceutical pollutants plays an important role in the persistence and activity of environmental bacteria.
Kelley M. Current, Niluka M. Dissanayake, Sherine O. Obare   +2 more
doaj   +1 more source