Results 51 to 60 of about 10,514 (181)

Molecular Characterization of AmpC β-lactamases in Enterobacteriaceae

open access: yesJournal of Pure and Applied Microbiology, 2022
AmpC β-lactamases are enzymes that are resistant to β-lactams, such as penicillin and cephalosporin, but not cefoxitin and cefotetan. This study was conducted to characterize AmpC β-lactamases in Enterobacteriaceae.
D. Bindu, Chitralekha Saikumar
doaj   +1 more source

Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
Molecular reversal strategies against antibiotic resistance act through three mechanisms: inhibiting resistance gene function, blocking horizontal gene transfer, and modulating host defense. Emerging technologies, such as CRISPR‐Cas gene editing, photodynamic therapy, nanotechnology, and ecological competition, further strengthen these approaches ...
Tianjiao Li   +4 more
wiley   +1 more source

Antibacterial Activity of Estragole From Ocimum tenuiflorum, and Tagetes lucida and Synergistic Effect With Meropenem and Tobramycin Against Multidrug‐ and Extensively Drug‐Resistant (MDR‐XDR) Gram‐Negative Bacteria

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study reveals estragole's bactericidal activity against MDR/XDR Gram‐negative pathogens. Synergy with meropenem and tobramycin was observed in > 88% of strains, reducing antibiotic MICs up to 16‐fold. Estragole represents a promising therapeutic adjuvant to enhance antibiotic efficacy and combat antimicrobial resistance.
María Araque, Luis B. Rojas
wiley   +1 more source

Genotypic and Phenotypic Detection of AmpC β-lactamases in Enterobacter spp. Isolated from a Teaching Hospital in Malaysia. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVES:The objective of this study was to determine the occurrence of chromosomal and plasmid-mediated β-lactamases (AmpC) genes in a collection of Malaysian isolates of Enterobacter species.
Fatin Izzati Mohd Khari   +3 more
doaj   +1 more source

The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2023–2024

open access: yesEFSA Journal, Volume 24, Issue 2, February 2026.
Abstract This report presents the main findings of the 2023–2024 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans, food‐producing animals (broilers, laying hens, fattening turkeys, fattening pigs and bovines under 1 year of age), and derived meat.
European Food Safety Authority (EFSA)   +1 more
wiley   +1 more source

Evaluation of Cefixime-Clavulanate Combination by Comparative Disk Diffusion Method in Klebsiella pneumoniae Clinical Isolates-An In-Vitro Study [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2015
Background: Resistance to cephalosporins due to β-lactamases is a major concern worldwide. However recent trend is to use β-lactamase inhibitor combinations. Potential combination is cefiximeclavulanate.
Gajul S.V   +4 more
doaj  

Cucumber Production System as a Reservoir for Clinically Important Extended‐Spectrum Beta‐Lactamase‐ and AmpC Beta‐Lactamase‐Producing Escherichia coli and Klebsiella pneumoniae Strains

open access: yesInternational Journal of Food Science, Volume 2026, Issue 1, 2026.
This study evaluated clinically significant extended‐spectrum β‐lactamase (ESBL)‐ and AmpC β‐lactamase (AmpC)‐ producing Escherichia coli and Klebsiella pneumoniae in a cucumber production system, focusing on their potential sources and public health implications.
Manana Dlangalala   +4 more
wiley   +1 more source

Antimicrobial Resistant Factors in Klebsiella pneumoniae Strains Isolated From Urinary Tract Infections, Wound Infections, Hospital Wastewater, and Cervical Cancers From Ghana, Togo, and Benin

open access: yesInternational Journal of Genomics, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is a Gram‐negative, facultatively anaerobic member of the Enterobacteriaceae that functions both as a gut commensal and a major opportunistic pathogen implicated in severe hospital and community‐acquired infections. The rapid global expansion of antimicrobial‐resistant K.
Biigba Yakubu, Santasree Banerjee
wiley   +1 more source

The Role of Short Journey Transportation in the Spreading of Swine Pathogens and Antimicrobial‐Resistant Bacteria

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The transport of live pigs poses a risk to on‐farm biosecurity. Trucks can carry pathogens with significant economic and health impacts, including antimicrobial‐resistant (AMR) bacteria. This study aimed to investigate the microbiological contamination of trucks before and after loading, focusing on AMR bacteria and other major pathogens transmissible ...
Marta Masserdotti   +11 more
wiley   +1 more source

Regulation of AmpC-Driven β-Lactam Resistance in Pseudomonas aeruginosa: Different Pathways, Different Signaling

open access: yesmSystems, 2019
The hyperproduction of the chromosomal AmpC β-lactamase is the main mechanism driving β-lactam resistance in Pseudomonas aeruginosa, one of the leading opportunistic pathogens causing nosocomial acute and chronic infections in patients with underlying ...
Gabriel Torrens   +6 more
doaj   +3 more sources

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