Results 71 to 80 of about 10,514 (181)

Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli

Biomolecules, 2020
Resistance to β-lactam antibacterials, importantly via production of β-lactamases, threatens their widespread use. Bicyclic boronates show promise as clinically useful, dual-action inhibitors of both serine- (SBL) and metallo- (MBL) β-lactamases.
Pauline A. Lang, Anete Parkova, Thomas M. Leissing, Karina Calvopiña, Ricky Cain, Alen Krajnc, Tharindi D. Panduwawala, Jules Philippe, Colin W. G. Fishwick, Peteris Trapencieris, Malcolm G. P. Page, Christopher J. Schofield, Jürgen Brem   +12 more
doaj   +1 more source

Microbiological Characteristics of Pathogens Isolated From Blood Cultures of Patients With Acute Cholangitis: Insights From Patients With Biliary‐Enteric Anastomosis

Journal of Hepato-Biliary-Pancreatic Sciences, Volume 32, Issue 10, Page 766-776, October 2025.
Kuhara and colleagues analyzed 366 cases of bacteremic acute cholangitis, focusing on pathogens isolated from blood cultures. Escherichia coli and Klebsiella spp. predominated overall, whereas ESCPM organisms were significantly more frequent in patients with prior biliary‐enteric anastomosis or intervention, highlighting the importance of considering ...
Yuta Kuhara, Hiroki Kitagawa, Yuki Kaiki, Keitaro Omori, Norifumi Shigemoto, Tomoyuki Akita, Kenichiro Uemura, Shingo Fukuma, Shinya Takahashi, Hiroki Ohge   +9 more
wiley   +1 more source

High prevalence of blaCMY AmpC beta-lactamase in ESBL co-producing Escherichia coli and Klebsiella spp. clinical isolates in the northeast of Iran

Journal of Global Antimicrobial Resistance, 2020
Objective: The production of β-lactamase enzymes such as AmpC β-lactamases and extended-spectrum β-lactamases (ESBLs) is among the main mechanisms for resistance to expanded-spectrum cephalosporins.
Kobra Salimiyan Rizi, Arman Mosavat, Masoud Youssefi, Saeid Amel Jamehdar, Kiarash Ghazvini, Hadi Safdari, Yousef Amini, Hadi Farsiani   +7 more
doaj   +1 more source

Characterization of plasmid mediated AmpC producing Escherichia coli clinical isolates from a tertiary care hospital in South India

Indian Journal of Pathology and Microbiology, 2014
Context: Plasmid mediated AmpC (pAmpC) β-lactamase producing Escherichia coli are an emerging problem worldwide as they are now exhibiting resistance to multiple classes of antibiotics and are a major cause of therapeutic failure.
Arindam Chakraborty, Prabha Adhikari, Shalini Shenoy, Vishwas Saralaya   +3 more
doaj   +1 more source

Comparison of susceptibility of Enterobacteriaceae causing community-onset urinary tract infection to isepamicin and amikacin by the disc diffusion method

Journal of Medical Sciences, 2014
Background: Enterobacteriaceae, common pathogens responsible for urinary tract infections are known to be susceptible to aminoglycosides. The emergence of resistant pathogens complicates antimicrobial regimen and becomes a challenge for clinicians.
Yung-Chih Wang, Ya-Sung Yang, Ti-Yin, Shu-Chen Kuo, Jung-Chung Lin, Feng-Yee Chang   +5 more
doaj   +1 more source

Extended spectrum and AmpC beta lactamases - Producing K. pneumoniae and Pseudomonas aeruginosa in Pediatric Care in Nepal

Nepal Journal of Biotechnology
Extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases are key mechanisms behind β-lactam antibiotic resistance, particularly in Gram-negative bacteria. In Nepal, antibiotic-resistant bacterial infections pose a growing public health concern among
Pratima Nyaupane, Rita Bista, Shovana Thapa, Bidya Shrestha   +3 more
doaj   +1 more source

Deletion of Lytic Transglycosylases Increases Beta-Lactam Resistance in Shewanella oneidensis

Frontiers in Microbiology, 2018
Production of chromosome-encoded β-lactamases confers resistance to β-lactams in many Gram-negative bacteria. Some inducible β-lactamases, especially the class C β-lactamase AmpC in Enterobacteriaceae, share a common regulatory mechanism, the ampR-ampC ...
Jianhua Yin, Jianhua Yin, Jianhua Yin, Yiyang Sun, Yijuan Sun, Zhiliang Yu, Juanping Qiu, Haichun Gao   +7 more
doaj   +1 more source

Comparative Study of Biofilm and Non-Biofilm Producing Klebsiella pneumoniae with Special Reference to Metallo-Beta-Lactamase Production

Journal of Pure and Applied Microbiology
Klebsiella pneumoniae is one of the most common bacteria among all biofilm-producing as well as the beta-lactamase producing strains, which is responsible for multi-drug resistance.
Prajakta S. Pawar, Satyajeet K. Pawar, Satish R. Patil, Harsha V. Patil, Priyanka M. Mane   +4 more
doaj   +1 more source

Molecular Detection of AmpC Family Genes Encoding Antibiotic Resistance among Escherichia coli isolated from Patients with Urinary Tract Infection (UTI) in Najaf Hospitals

Kufa Journal for Veterinary Medical Sciences, 2013
    One hundred and thirty significant bacteriuria were detected. The study showed higher incidence of UTI in females (73.08%) than males (26.9%). The E.
Abeer Mohammed Ali AL-karawyi, Salman Aziz AL-Jubouri, Yassir D. K. Alasadiy   +2 more
doaj   +1 more source

Occurrence of extended spectrum β-lactamase and AmpC-producing Escherichia coli in retail meat products from the Maritime Provinces, Canada [PDF]

, 2020
Babafela Awosile, Jessica Eisnor, Matthew E. Saab, Luke C. Heider, J. Trenton McClure   +4 more
openalex   +1 more source