Background Phosphodiesterase 10A (PDE10A) is an important regulator of nigrostriatal dopamine (DA) neurotransmission. However, little is known on the effect of alterations in DA neurotransmission on PDE10A availability. Here, we used [18F]JNJ42259152 PET
Maarten Ooms +11 more
doaj +1 more source
Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]
Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P +11 more
core +1 more source
Recurrent Syncope following Substance Abuse; a Case Report
Drug abuse is considered as the most common poisoning in the world. Stimulants agent especially amphetamines and methamphetamines are among important abused substances.
Forod Salehi +3 more
doaj +3 more sources
Neural Models of Normal and Abnormal Behavior: What Do Schizophrenia, Parkinsonism, Attention Deficit Disorder, and Depression Have in Common? [PDF]
Defense Advanced Research Projects Agency and Office of Naval Research (N00014-95-1-0409); National Science Foundation (IRI-97 ...
Abbott +177 more
core +2 more sources
Cognitive-behavioural treatment for amphetamine-type stimulants (ATS)-use disorders.
BACKGROUND Amphetamine-type stimulants (ATS) refer to a group of synthetic stimulants including amphetamine, methamphetamine, 3,4-methylenedioxy-methamphetamine (MDMA) and related substances.
T. Harada +3 more
semanticscholar +1 more source
Time Perception and Psychiatric Disorders [PDF]
Time perception is an ability which we use in every moment of daily life, that guides the formation and continuation of our behaviors and from an evolutionary perspective ensures survival. Internal clock models help us to understand time perception. Time
Hatice Ceviz +3 more
doaj +1 more source
Amphetamine, but not methylphenidate, increases ethanol intake in adolescent male, but not in female, rats [PDF]
Introduction: There has been an increasing interest in analyzing the interactions between stimulants and ethanol during childhood and adolescence. Stimulants are used to treat attention-deficit hyperactivity disorder (ADHD) in these developmental stages,
Acevedo +77 more
core +1 more source
Cognitive‐behavioural treatment for amphetamine‐type stimulants (ATS)‐use disorders
Background Amphetamine‐type stimulants (ATS) refer to a group of synthetic stimulants including amphetamine, methamphetamine, 3,4‐methylenedioxy‐methamphetamine (MDMA) and related substances.
Takayuki Harada +3 more
semanticscholar +1 more source
Amphetamine alters the Reward Positivity in humans and mice
The development of pro-cognitive therapeutics for psychiatric disorders has been beset with difficulties. This is in part due to the absence of pharmacologically-sensitive cognitive biomarkers common to humans and rodents.
J. Cavanagh +12 more
semanticscholar +1 more source
Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users. [PDF]
Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors influence amphetamine-induced dopamine release and that dopamine is involved in ...
Dean, AC +5 more
core +4 more sources

