Results 131 to 140 of about 123,317 (298)

Substance Use Disorders in Adolescents: A Qualitative Systematic Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Introduction It is important for the treatment and care of adolescents using substances to bring out their life experiences relating to substance use. Aim To analyse and synthesise qualitative evidence on substance use‐related life experiences of adolescents with substance use disorder.
Hilal Kara, Dudu Karakaya
wiley   +1 more source

How to Diagnose Prisons' Failures: Three Perspectives on Officers' Responsibilities

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Prison officers play a vital role in shaping prison conditions. Assessing their responsibility for, and potential role in reforming, the prison's failures is an urgent and important task in corrective justice efforts. This article takes up this task, with a focus on the US prison context, by applying and critically examining two general ...
Candice Delmas
wiley   +1 more source

Amphetamine use and Parkinson's disease: integration of artificial intelligence prediction, clinical corroboration, and mechanism of action analyses.

open access: yesPLoS ONE
Parkinson's disease (PD) is an increasingly prevalent neurologic condition for which symptomatic, but not preventative, treatment is available. Drug repurposing is an innovate drug discovery method that uncovers existing therapeutics to treat or prevent ...
Maria P Gorenflo   +4 more
doaj   +1 more source

Selective fiber used for headspace solid-phase microextraction of abused drugs in human urine [PDF]

open access: yesMaejo International Journal of Science and Technology, 2007
A sensitive and selective fiber for simultaneous analysis of three drugs of abuse (amphetamine, methamphetamine and ephedrine) in urine samples was explored using headspace solid phase microextraction and gas chromatography with flame ionization ...
Sunanta Wangkarn
doaj  

Psychostimulant treatment uniquely reduces left uncinate fasciculus microstructural integrity in ADHD youth with a familial risk for bipolar I disorder: a 12‐week DTI study

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Bipolar I disorder (BD) is associated with reduced white matter microstructural integrity in the uncinate fasciculus (UF), a primary fiber tract connecting frontolimbic systems. Although familial history for BD, attention‐deficit/hyperactivity disorder (ADHD), and psychostimulants are important risk factors implicated in BD pathoetiology ...
Kun Qin   +10 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini   +4 more
wiley   +1 more source

A Review of the Effects of Maternal and Paternal Obesity on Neurodevelopmental Disorders and Related Neurobiology in Rodent and Human Offspring

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is one of the most prevalent health problems worldwide, and global obesity rates continue to rise. Consequently, rates of obesity in expecting mothers and fathers have also increased. The Developmental Origins of Health and Disease (DOHaD) hypothesis postulates that early‐life exposure to adverse environmental conditions contributes to
Hannah Chadwick   +3 more
wiley   +1 more source

How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang   +3 more
wiley   +1 more source

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