Results 151 to 160 of about 106,948 (272)

Personality Pathology and Functional Outcomes During Pharmacological Treatment of Adult ADHD

open access: yesPersonality and Mental Health, Volume 20, Issue 2, May 2026.
ABSTRACT Adults with ADHD show substantial variability in response to pharmacological treatment, and comorbid personality pathology may help explain why symptom improvement often fails to translate into meaningful functional improvement. This naturalistic longitudinal study examined whether dimensional personality pathology predicts symptomatic and ...
Peter Jacobsson   +6 more
wiley   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos   +3 more
wiley   +1 more source

Improving drug identification in overdose death surveillance by using clinical natural language processing models

open access: yesJournal of Forensic Sciences, Volume 71, Issue 3, Page 1329-1337, May 2026.
Abstract The rising rate of drug‐related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free‐text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)‐10 classifications.
Arthur J. Funnell   +8 more
wiley   +1 more source

Trends in toxicological findings and drug seizures of MDMA in New Zealand from 2010 to 2022

open access: yesJournal of Forensic Sciences, Volume 71, Issue 3, Page 1338-1350, May 2026.
Abstract 3,4‐Methylenedioxymethamphetamine (MDMA) or “ecstasy,” is a commonly used drug worldwide, including in New Zealand, where 4.8% of the population aged 15 years or over reported using it in a 2023/2024 survey. This study provides additional insights on MDMA prevalence data in New Zealand by reporting toxicology data from Coronial and driving ...
Thomas J. Sheehan   +4 more
wiley   +1 more source

A meta‐analysis of sexual orientation inequities in substance use among youth

open access: yesAddiction, Volume 121, Issue 5, Page 1048-1063, May 2026.
Abstract Background and Aims Sexual minority youth report significantly higher rates of substance use than heterosexual youth, yet a comprehensive and systematic evaluation and synthesis of the magnitude of this inequity has not been conducted. The purpose of this study was to conduct a meta‐analysis to assess the magnitude of overall inequities in ...
Ethan H. Mereish   +4 more
wiley   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 2123-2138, May 2026.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan   +2 more
wiley   +1 more source

Maternal anorexia nervosa and risk of mental and neurodevelopmental morbidity in offspring

open access: yesChild and Adolescent Mental Health, Volume 31, Issue 2, Page 125-133, May 2026.
Background Anorexia nervosa has the potential to affect fetal neurodevelopment. We examined the association between maternal anorexia nervosa and mental, substance‐related, and neurodevelopmental morbidity in offspring. Methods We conducted a retrospective cohort study of 1,269,370 children in Quebec, Canada, between 2006 and 2022.
Sam Amar   +8 more
wiley   +1 more source

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