D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats [PDF]
Frontiers in Pharmacology, 2021 D-amphetamine induces emergence from sevoflurane and propofol anesthesia in rats. Dexmedetomidine is an α2-adrenoreceptor agonist that is commonly used for procedural sedation, whereas ketamine is an anesthetic that acts primarily by inhibiting NMDA-type
Risako Kato +18 more
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The effects of caffeine and d-amphetamine on spatial span task in healthy participants. [PDF]
PLoS ONE, 2023 Studies that examined the effect of amphetamine or caffeine on spatial working memory (SWM) and verbal working memory (VWM) have used various tasks.
Faiz M Kassim +9 more
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Effects of Lisdexamfetamine, a Prodrug of D-Amphetamine, on Locomotion, Spatial Cognitive Processing and Neurochemical Profiles in Rats: A Comparison With Immediate-Release Amphetamine [PDF]
Frontiers in Psychiatry, 2022 D-amphetamine has been used to enhance cognitive performance over the last few decades. Due to the rapid absorption after administration, d-amphetamine shows narrow effective window and severe abuse potential. Lisdexamfetamine, a prodrug of d-amphetamine,
Chen Jian-min +5 more
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D-Amphetamine Accelerates Recovery of Consciousness and Respiratory Drive After High-Dose Fentanyl in Rats [PDF]
Frontiers in Pharmacology, 2020 In the United States, fentanyl causes approximately 60,000 drug overdose deaths each year. Fentanyl is also frequently administered as an analgesic in the perioperative setting, where respiratory depression remains a common clinical problem.
Olivia A. Moody +10 more
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D-amphetamine alters the dynamic ECoG activity distribution patterns in the rat neocortex [PDF]
Scientific ReportsAmphetamine has widespread effects on multiple neurotransmitter systems, potentially altering the physiological connectivity and network dynamics across various regions of the brain.
Astrid Mellbin +2 more
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Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day. [PDF]
PLoS ONE, 2011 BackgroundThe neurochemical status and hyperactivity of mice lacking functional substance P-preferring NK1 receptors (NK1R-/-) resemble abnormalities in Attention Deficit Hyperactivity Disorder (ADHD).
Ting Carrie Yan +8 more
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Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects [PDF]
Frontiers in Pharmacology, 2017 Rationale: Lisdexamfetamine is a prodrug of D-amphetamine used for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is thought to have a prolonged pharmacokinetic profile compared with oral D-amphetamine, possibly ...
Patrick C. Dolder +5 more
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Adolescent THC exposure does not sensitize conditioned place preferences to subthreshold d-amphetamine in male and female rats [version 2; referees: 2 approved] [PDF]
F1000Research, 2018 The acute effects of marijuana consumption on brain physiology and behaviour are well documented, but the long-term effects of its chronic use are less well known. Chronic marijuana use during adolescence is of increased interest, given that the majority
Robin J Keeley +3 more
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d‐Amphetamine and Feeding States Cohesively Affect Locomotion and Motor Neuron Response in Zebrafish Larvae [PDF]
Brain and BehaviorPurpose Amphetamine (AMPH) increases locomotor activities in animals, and the locomotor response to AMPH is further modulated by caloric deficits such as food deprivation and restriction.
Pushkar Bansal +2 more
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Amphetamine Promotes Cortical Up State in Part Via Dopamine Receptors
Frontiers in Pharmacology, 2021 Cortical neurons oscillate between Up and Down states during slow wave sleep and general anesthesia. Recent studies show that Up/Down oscillations also occur during quiet wakefulness.
Guofang Shen, Wei-Xing Shi, Wei-Xing Shi
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