Results 31 to 40 of about 13,512,755 (196)
Neuropsychopharmacology Reports, 2020 Aim To assess safety, tolerability, and pharmacokinetics of lisdexamfetamine dimesylate in Japanese and Caucasian healthy adults. Methods A phase 1, double‐blind, randomized, placebo‐controlled, single‐ and multiple‐dose study in Japanese and Caucasian ...
James Ermer +3 more
doaj +1 more source
EJNMMI Radiopharmacy and Chemistry, 2016 Background Phosphodiesterase 10A (PDE10A) is an important regulator of nigrostriatal dopamine (DA) neurotransmission. However, little is known on the effect of alterations in DA neurotransmission on PDE10A availability. Here, we used [18F]JNJ42259152 PET
Maarten Ooms +11 more
doaj +1 more source
A Mechanistic Study on Urine Retention in D-Amphetamine Addicts
, 2017 Chronic amphetamine intake leads to neurogenic bladder and chronic urinary retention. The mechanism underlying persistent urinary retention is unclear.
陳宜明;張榮珍 +1 more
core +1 more source
Frontiers in Pharmacology, 2017 Marijuana is currently the most commonly abused illicit drug. According to recent studies, cannabinoid use occurring prior to pregnancy can impact brain plasticity and behavior in future generations.
George Panagis +3 more
doaj +1 more source
Modulation of mGlu2 Receptors, but Not PDE10A Inhibition Normalizes Pharmacologically-Induced Deviance in Auditory Evoked Potentials and Oscillations in Conscious Rats. [PDF]
PLoS ONE, 2016 Improvement of cognitive impairments represents a high medical need in the development of new antipsychotics. Aberrant EEG gamma oscillations and reductions in the P1/N1 complex peak amplitude of the auditory evoked potential (AEP) are neurophysiological
Abdallah Ahnaou +2 more
doaj +1 more source
F1000Research, 2018 The acute effects of marijuana consumption on brain physiology and behaviour are well documented, but the long-term effects of its chronic use are less well known. Chronic marijuana use during adolescence is of increased interest, given that the majority
Robin J Keeley +3 more
doaj +1 more source
Spontaneous alternation and D-amphetamine [PDF]
Psychonomic Science, 1969 Forty male rats were tested for spontaneous alternation in a Tmaze following doses of d-amphetamine sulfate, ranging from 1.0 to 4.0mg/kg.
Joel Adkins +2 more
openaire +1 more source
Effects of d-Amphetamine on the Electroencephalogram of the Dog.
Experimental Biology and Medicine, 1953 Summary(1) In dogs prepared under thiopental and then immobilized with C10, the injection of d-amphetamine causes a progressive increase in the frequency of the EEG, with a corresponding decrease in amplitude. These effects are maximal within the first hour.
W, SCHALLEK, D, WALZ
openaire +2 more sources
Amphetamine-induced locomotor activity in GIT1 deficient mice.
, 2018 GIT1 WT (black circle) and GIT1 KO (open square) mice on a mixed genetic background were habituated to the locomotor chamber for 60 min prior to amphetamine injection.
Amanda C. Martyn (777373) +7 more
core +1 more source
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). [PDF]
PLoS ONE, 2012 Both the subjective response to d-amphetamine and the risk for amphetamine addiction are known to be heritable traits. Because subjective responses to drugs may predict drug addiction, identifying alleles that influence acute response may also provide ...
Amy B Hart +6 more
doaj +1 more source