Results 51 to 60 of about 42,834 (276)

Effect of Reaction Time and Temperature on the Impurity Profile of Amphetamine in the Leuckart Method

open access: yesDrug Testing and Analysis, EarlyView.
This study investigates the effect of the reaction temperature (step 1) and reaction time (step 1 and 2) on the conversion efficiency and impurity profile of amphetamine synthesized via the Leuckart method. Conversion efficiency and impurity profile were assessed using gas chromatography–flame ionization detection (GC–FID) and GC–mass spectrometry (GC ...
Maartje C. M. Verhoeven   +7 more
wiley   +1 more source

Dissociating Allopregnanolone Mnemonic Effects from Sedation [PDF]

open access: yes, 2012
Allopregnanolone (Allop) is a neurosteroid metabolite of progesterone. Allop modulates cognition, specifically learning and memory, but these effects are frequently confounded by its anxiolytic and sedative properties.
Hartman, Sarah B
core   +1 more source

Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]

open access: yes, 2015
Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO   +2 more
core   +1 more source

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

open access: yesDrug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão   +4 more
wiley   +1 more source

Alleviation of Brain Injury-Induced Cerebral Metabolic Depression by Amphetamine: A Cytochrome Oxidase Histochemistry Study

open access: yesNeural Plasticity, 2000
Measurements of oxidative metabolic capacity following the ablation of rat sensorimotor cortex and ,he administration of amphetamine were examined to determine their effects on the metabolic dysfunction that follows brain injury.
Richard L. Sutton   +3 more
doaj   +1 more source

Alteration of striatal dopaminergic neurotransmission in a mouse model of DYT11 myoclonus-dystonia. [PDF]

open access: yesPLoS ONE, 2012
DYT11 myoclonus-dystonia (M-D) syndrome is a neurological movement disorder characterized by myoclonic jerks and dystonic postures or movement that can be alleviated by alcohol.
Lin Zhang   +4 more
doaj   +1 more source

Significance of Dopamine Transmission in the Rat Medial Prefrontal Cortex for Conditioned Fear [PDF]

open access: yes, 2017
Previous studies have demonstrated activation of dopamine transmission in the medial prefrontal cortex (mPFC) by conditioned fear stimuli. Therefore, the present study investigated the functional significance of mPFC dopamine for a conditioned fear ...
Bast, Tobias   +2 more
core  

Differences in patterns of attention deficit/hyperactivity disorder medication use in US children

open access: yesJCPP Advances, EarlyView.
Abstract Background Understanding attention deficit/hyperactivity disorder (ADHD) medication patterns is crucial for optimizing treatment outcomes. There are limited data on racial, ethnic, gender and socioeconomic treatment differences across longitudinal national samples.
Jennie E. Ryan   +4 more
wiley   +1 more source

Role of the ERK pathway in psychostimulant-induced locomotor sensitization

open access: yesBMC Neuroscience, 2006
Background Repeated exposure to psychostimulants results in a progressive and long-lasting facilitation of the locomotor response that is thought to have implications for addiction.
Girault Jean-Antoine   +4 more
doaj   +1 more source

Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake [PDF]

open access: yes, 2006
Repeated administration of abused drugs sensitizes their stimulant effects and results in a drug-paired environment eliciting conditioned activity. We tested whether food induces similar effects.
Le Merrer, Julie, Stephens, David N
core   +1 more source

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