Results 61 to 70 of about 14,369,746 (295)
, 2003 The dopaminergic response to d-amphetamine with or without prior repeated experience with the drug was investigated immunohistochemically in key target regions of the mesotelencephalic dopamine system using antibodies raised against glutaraldehyde ...
Phillips, G. D +5 more
core +1 more source
Estimating Illicit Stimulant Drug Consumption in Luxembourg Using Wastewater‐Based Epidemiology
Drug Testing and Analysis, EarlyView.Wastewater‐based epidemiology provided nationwide estimates of illicit stimulant consumption in Luxembourg, revealing higher urban use, weekend increases in cocaine and MDMA, and cocaine as the dominant stimulant. The approach offers an objective complement to conventional drug surveillance for informing public health and policy.
Nadine Berndt +5 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani +6 more
wiley +1 more source
Effects of N-acetylcysteine on amphetamine-induced sensitization in mice
Brazilian Journal of Psychiatry, 2017 Objective: N-acetylcysteine (NAC) is beneficial in psychiatric conditions, including schizophrenia. Patients with schizophrenia exhibit mesolimbic dopamine hyperfunction consequent to an endogenous sensitization process. This sensitization can be modeled
Ana P. Herrmann +4 more
doaj +1 more source
d-Amphetamine Reinstates Behavior Previously Maintained by Food: Importance of Context
, 2004 The drug self-administration reinstatement procedure provides an important animal model of relapse. While the procedure is widely used, there has been little investigation of the basic processes involved.
A. L. Odum +3 more
core +1 more source
Drug Testing and Analysis, EarlyView.A decision model for the interpretation of chiral amphetamine analysis in hair was established based on the enantiomeric fraction (EF) of (S)‐amphetamine in authentic hair samples. Two chiral analysis methods (indirect/direct) were consecutively applied to distinguish between illicit and therapeutic amphetamine use in forensic cases.
Liesl K. Janssens +3 more
wiley +1 more source
The Role of Nitrous Oxide (“Laughing Gas”) in DUID Cases and Its Impact on Driving Fitness
Drug Testing and Analysis, EarlyView.A total number of 39 cases of driving under the influence of nitrous oxide were investigated. Plasma concentrations of 0.22 to 17 mL/L (median:3.7 mL/L) were measured in blood samples withdrawn 38 to 144 min (median: 85 min) after control via Headspace‐GC–MS.
L. Lucuta +4 more
wiley +1 more source
Neurobiology of Disease, 2020 Cerebral dopamine neurotrophic factor (CDNF) is neuroprotective for nigrostriatal dopamine neurons and restores dopaminergic function in animal models of Parkinson's disease (PD). To understand the role of CDNF in mammals, we generated CDNF knockout mice
Maria Lindahl +16 more
doaj +1 more source
Long-Term Stimulant Therapy and ADHD Outcome
Pediatric Neurology Briefs, 1997 The long-term effects of amphetamine sulfate (5 mg AM and lunchtime, increasing to a mean dose of 17 mg/d, 0.52 mg/kg body weight, and a maximum of 45 mg/d) were evaluated in 62 children, aged 6 to 11 years, with ADHD treated for 15 months in a ...
J Gordon Millichap
doaj +1 more source
Functional magnetic resonance imaging reveals different neural substrates for the effects of orexin-1 and orexin-2 receptor antagonists. [PDF]
PLoS ONE, 2011 Orexins are neuro-modulatory peptides involved in the control of diverse physiological functions through interaction with two receptors, orexin-1 (OX1R) and orexin-2 (OX2R).
Alessandro Gozzi +11 more
doaj +1 more source