Results 21 to 30 of about 13,512,755 (196)

Effects of Food on the Bioavailability of Amphetamine in Healthy Adults After Administration of SHP465 Mixed Amphetamine Salts Extended-Release Capsules

open access: yesDrugs in R&D, 2019
Background and objective SHP465 mixed amphetamine salts extended release is a once-daily, single-entity, mixed amphetamine salts capsule product for attention-deficit/hyperactivity disorder.
Yi Wang   +4 more
doaj   +1 more source

l-Amphetamine improves poor sustained attention while d-amphetamine reduces overactivity and impulsiveness as well as improves sustained attention in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)

open access: yesBehavioral and Brain Functions, 2008
Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinical symptoms.
Xu Tong, Sagvolden Terje
doaj   +1 more source

Alterations of Amphetamine Reward by Prior Nicotine and Alcohol Treatment: The Role of Age and Dopamine

open access: yesBrain Sciences, 2021
Evidence suggests that nicotine and alcohol can each serve as a gateway drug. We determined whether prior nicotine and alcohol treatment would alter amphetamine reward.
Andrea Stojakovic   +2 more
doaj   +1 more source

Riluzole and d-amphetamine interactions in humans [PDF]

open access: yesProgress in Neuro-Psychopharmacology and Biological Psychiatry, 2008
In preclinical studies, medications which decrease glutamate release have been shown to block some of the effects of psychostimulants. One such medication is riluzole, marketed for the treatment of Amyotrophic Lateral Sclerosis (ALS). The goal of this study was to determine riluzole's effects on acute physiological and subjective responses to d ...
Mehmet, Sofuoglu   +3 more
openaire   +2 more sources

Serum Metabolomic Analysis of Male Patients with Cannabis or Amphetamine Use Disorder

open access: yesMetabolites, 2022
Studies have demonstrated that chronic consumption of abused drugs induces alterations in several proteins that regulate metabolism. For instance, methamphetamine exposure reduces glucose levels. Fatty and amino acid levels were altered in groups exposed
Fawaz Alasmari   +9 more
doaj   +1 more source

Combination of modafinil and d-Amphetamine for the treatment of cocaine dependence: A preliminary investigation

open access: yesFrontiers in Psychiatry, 2012
Background: Two stimulant medications, modafinil and d-amphetamine, when tested individually, have shown safety and efficacy for treatment of cocaine addiction.
Joy M Schmitz   +5 more
doaj   +1 more source

Dopamine-mediated striatal activity and function is enhanced in GlyRα2 knockout animals

open access: yesiScience, 2023
Summary: The glycine receptor alpha 2 (GlyRα2) is a ligand-gated ion channel which upon activation induces a chloride conductance. Here, we investigated the role of GlyRα2 in dopamine-stimulated striatal cell activity and behavior. We show that depletion
Jens Devoght   +12 more
doaj   +1 more source

Amantadine Decreases d-Amphetamine Stimulation and Increases d-Amphetamine Anorexia in Mice

open access: yesExperimental Biology and Medicine, 1976
Amantadine hydrochloride (Symmetrel), an antiviral, antiparkinson agent that is most frequently used clinically at oral doses of 2 to 3 mg/kg, significantly decreased d-amphetamine-induced CNS stimulation (motor activity) and simultaneously increased d-amphetamine-induced anorexia (milk intake) in mice. Amantadine did this at oral doses of 2.5 and 5 mg/
R, Clark   +3 more
openaire   +2 more sources

Comparison of the efficacy of two anticonvulsants, phenytoin and valproate to improve PCP and d-amphetamine induced deficits in a reversal learning task in the rat

open access: yesFrontiers in Behavioral Neuroscience, 2009
Recent studies in our laboratory have shown that PCP (phencyclidine) and d-amphetamine induce a cognitive deficit in rats, in a paradigm of potential relevance for the pathology of schizophrenia.
Nagi F Idris   +2 more
doaj   +1 more source

Speeding stroke recovery? A systematic review of amphetamine after stroke [PDF]

open access: yes, 2009
Introduction: The use of drugs to enhance recovery (“rehabilitation pharmacology”) has been assessed. Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke.
Nikola Sprigg   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy