Results 21 to 30 of about 14,369,746 (295)

Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects. [PDF]

Neuropsychopharmacology, 2020
Lysergic acid diethylamide (LSD) is a classic psychedelic, 3,4-methylenedioxymethamphetamine (MDMA) is an empathogen, and D-amphetamine is a classic stimulant. All three substances are used recreationally.
Holze F, Vizeli P, Müller F, Ley L, Duerig R, Varghese N, Eckert A, Borgwardt S, Liechti ME.   +8 more
europepmc   +2 more sources

Amphetamine Promotes Cortical Up State in Part Via Dopamine Receptors

Frontiers in Pharmacology, 2021
Cortical neurons oscillate between Up and Down states during slow wave sleep and general anesthesia. Recent studies show that Up/Down oscillations also occur during quiet wakefulness.
Guofang Shen, Wei-Xing Shi, Wei-Xing Shi
doaj   +1 more source

Interactions Between Opioids and Dextroamphetamine on Locomotor Activity: Influence of an Opioid's Relative Efficacy at the Mu Receptor

Frontiers in Psychiatry, 2022
Opioids and stimulants are often used in combination for both recreational and non-recreational purposes. High-efficacy mu opioid agonists generally increase the behavioral effects of stimulants, whereas opioid receptor antagonists generally attenuate ...
Mark A. Smith, Shannon L. Ballard, Clarise F. Ballesteros, Samantha A. Bonge, Alexander T. Casimir, Lauren M. Childs, Max A. Feinstein, Annie K. Griffith, Alexandra N. Johansen, Daegeon Lee, A. Caroline Mauser, Cassidy M. Moses, Ian J. Robertson, Javier U. Robles, Justin C. Strickland, Mary E. Walters, Seeley J. Yoo   +16 more
doaj   +1 more source

Amphetamine and pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats [PDF]

, 2008
Background Pseudoephedrine is a drug commonly prescribed as a nasal decongestant and bronchodilator and is also freely available in cold remedies and medications.
Tongjaroenbuangam, W., Nootchanart Ruksee, Govitrapong, P., Casalotti Stefano O, Ruksee Nootchanart, Walaiporn Tongjaroenbuangam, Nootchanart Ruksee, Govitrapong Piyarat, Casalotti, Stefano O., Ruksee, N., Piyarat Govitrapong, Tongjaroenbuangam Walaiporn, Stefano O Casalotti   +12 more
core   +1 more source

Riluzole and d-amphetamine interactions in humans [PDF]

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2008
In preclinical studies, medications which decrease glutamate release have been shown to block some of the effects of psychostimulants. One such medication is riluzole, marketed for the treatment of Amyotrophic Lateral Sclerosis (ALS). The goal of this study was to determine riluzole's effects on acute physiological and subjective responses to d ...
Mehmet, Sofuoglu, Andrew J, Waters, Marc, Mooney, Thomas, Kosten   +3 more
openaire   +2 more sources

Nicotine and Amphetamine Decrease Sucrose Self-Administration

, 2023
Limited research exists on how amphetamine and nicotine, drugs with potent influences on feeding behaviors, impact the rewarding and pleasurable aspects of feeding.
Fulco, Cameron
core   +1 more source

Amantadine Decreases d-Amphetamine Stimulation and Increases d-Amphetamine Anorexia in Mice

Experimental Biology and Medicine, 1976
Amantadine hydrochloride (Symmetrel), an antiviral, antiparkinson agent that is most frequently used clinically at oral doses of 2 to 3 mg/kg, significantly decreased d-amphetamine-induced CNS stimulation (motor activity) and simultaneously increased d-amphetamine-induced anorexia (milk intake) in mice. Amantadine did this at oral doses of 2.5 and 5 mg/
R, Clark, D H, Smith, V G, Vernier, A A, Rubin   +3 more
openaire   +2 more sources

A phase 1, randomized, double‐blind, placebo‐controlled study to evaluate the safety, tolerability, and pharmacokinetics of single and multiple doses of lisdexamfetamine dimesylate in Japanese and Caucasian healthy adult subjects

Neuropsychopharmacology Reports, 2020
Aim To assess safety, tolerability, and pharmacokinetics of lisdexamfetamine dimesylate in Japanese and Caucasian healthy adults. Methods A phase 1, double‐blind, randomized, placebo‐controlled, single‐ and multiple‐dose study in Japanese and Caucasian ...
James Ermer, Patrick Martin, Mary Corcoran, Yumiko Matsuo   +3 more
doaj   +1 more source

Striatal phosphodiesterase 10A availability is altered secondary to chronic changes in dopamine neurotransmission

EJNMMI Radiopharmacy and Chemistry, 2016
Background Phosphodiesterase 10A (PDE10A) is an important regulator of nigrostriatal dopamine (DA) neurotransmission. However, little is known on the effect of alterations in DA neurotransmission on PDE10A availability. Here, we used [18F]JNJ42259152 PET
Maarten Ooms, Sofie Celen, Ronald De Hoogt, Ilse Lenaerts, Johnny Liebregts, Greet Vanhoof, Xavier Langlois, Andrey Postnov, Michel Koole, Alfons Verbruggen, Koen Van Laere, Guy Bormans   +11 more
doaj   +1 more source

A Mechanistic Study on Urine Retention in D-Amphetamine Addicts

, 2017
Chronic amphetamine intake leads to neurogenic bladder and chronic urinary retention. The mechanism underlying persistent urinary retention is unclear.
陳宜明;張榮珍, Chiu, Hui-Fang;Cheng, Jen-Kun;Lin, Pu-Hua;Chang, Jung-Chen;Chen, I-Ming;Lin, Ching-I;Chang, Wei-Pin;Lin, Chia-Hsien   +1 more
core   +1 more source