Necessity for research directed at stimulant type and treatment-onset age to access the impact of medication on drug abuse vulnerability in teenagers with ADHD [PDF]
, 2016 Controversy continues regarding increased vulnerability for addiction to cocaine and other drugs of abuse in adulthood following the use of stimulant medications for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
Dwoskin, Linda P., Kantak, Kathleen M.
core +1 more source
Frontiers in Psychiatry, 2012 Background: Two stimulant medications, modafinil and d-amphetamine, when tested individually, have shown safety and efficacy for treatment of cocaine addiction.
Joy M Schmitz +5 more
doaj +1 more source
Dopamine-mediated striatal activity and function is enhanced in GlyRα2 knockout animals
iScience, 2023 Summary: The glycine receptor alpha 2 (GlyRα2) is a ligand-gated ion channel which upon activation induces a chloride conductance. Here, we investigated the role of GlyRα2 in dopamine-stimulated striatal cell activity and behavior. We show that depletion
Jens Devoght +12 more
doaj +1 more source
Riluzole and d-amphetamine interactions in humans [PDF]
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2008 In preclinical studies, medications which decrease glutamate release have been shown to block some of the effects of psychostimulants. One such medication is riluzole, marketed for the treatment of Amyotrophic Lateral Sclerosis (ALS). The goal of this study was to determine riluzole's effects on acute physiological and subjective responses to d ...
Mehmet, Sofuoglu +3 more
openaire +2 more sources
Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat [PDF]
, 2010 YesBackground: Asenapine is a new pharmacological agent for the acute treatment of schizophrenia and bipolar disorder. It has relatively higher affinity for serotonergic and α2-adrenergic than dopaminergic D2 receptors.
Abdul-Monim +62 more
core +1 more source
Frontiers in Behavioral Neuroscience, 2009 Recent studies in our laboratory have shown that PCP (phencyclidine) and d-amphetamine induce a cognitive deficit in rats, in a paradigm of potential relevance for the pathology of schizophrenia.
Nagi F Idris +2 more
doaj +1 more source
Spontaneous alternation and D-amphetamine [PDF]
Psychonomic Science, 1969 Forty male rats were tested for spontaneous alternation in a Tmaze following doses of d-amphetamine sulfate, ranging from 1.0 to 4.0mg/kg.
Joel Adkins +2 more
openaire +1 more source
Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors [PDF]
, 2010 Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD).
Bermeo, C. +6 more
core +1 more source
Does Zinc Moderate Essential Fatty Acid and Amphetamine Treatment of Attention-Deficit/Hyperactivity Disorder? [PDF]
, 2000 Zinc is an important co-factor for metabolism relevant to neurotransmitters, fatty acids, prostaglandins, and melatonin, and indirectly affects dopamine metabolism, believed intimately involved in attention-deficit/hyperactivity disorder (ADHD).
Arnold, L. Eugene +2 more
core +1 more source
‘Waiting impulsivity’ in isolation-reared and socially-reared rats: effects of amphetamine [PDF]
, 2011 Background Rats reared in social isolation exhibit various cognitive and behavioural abnormalities in adulthood. However, impulsivity following this treatment still remains unclear, especially in response to medications used in attention deficit ...
Charkin, Alexander +7 more
core +3 more sources