Results 131 to 140 of about 106,948 (272)

Using an Adapted Job Demands–Resources Model to Examine the Use of Legal, Prescription, and Illegal Drugs for Cognitive Enhancement in the Working Population in Germany

Sociological Inquiry, EarlyView.
Chronic stress is a global issue with detrimental effects on health and productivity, often leading individuals to adopt health‐related coping strategies. This study uses an adapted Job Demands–Resources model to examine how various job demands and resources impact perceived stress and, consequently, the use of legal, prescription, and illegal drugs ...
Sebastian Sattler, Mareike Reimann, Myriam Baum, Nina Hänel   +3 more
wiley   +1 more source

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

Experimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin, Jean‐Christophe Lagacé, Mathil Ruel, Ahmed Ghachem, Guillaume Léonard, Eleonor Riesco, Mathew Piasecki, Jamie S. McPhee, Isabelle J. Dionne   +8 more
wiley   +1 more source

Female rat hippocampal cell density after conditioned place preference [PDF]

, 2014
The hippocampus is important for learning tasks, such as conditioned place preference (CPP), which is widely used as a model for studying the reinforcing effects of drugs with dependence liability.
Babakordi, F., Jahanshahi, M., Nikmahzar, E.G., Shabani, R.   +3 more
core  

Psychotropic medication and the fetal brain

The Journal of Physiology, EarlyView.
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley   +1 more source

A New Kinetic‐Mechanistic Approach Towards Spectrophotometric Bioanalysis of 2‐Phenylethylamine as a Sympathomimetic Agent Using Sodium Isopropyl Xanthate

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT 2‐Phenylethylamine (2‐PEA), an aromatic biogenic amine, demonstrates significant physiological and toxicological effects on human health. A variety of conventional methods have been widely used for the determination of 2‐PEA. However, the necessity of complex sample preparation and high cost of instrumentation may pose challenges to their ...
Fatemeh Nami, Houman Kholafazad, Mohammad Hasanzadeh, Nasrin Shadjou   +3 more
wiley   +1 more source

Distinct Effects of Nonselective Rho‐Kinase Inhibitor Fasudil and Selective Rho‐Kinase 2 Inhibitor KD025 on Serotonin and Dopamine Release in the Nucleus Accumbens of Mice

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Fasudil perfusion in the NAc increased basal extracellular serotonin but not dopamine, and suppressed depolarization‐evoked release of both. In contrast, KD025 showed minimal effects on basal levels and selectively suppressed evoked serotonin release. ABSTRACT Recent studies have indicated that the Rho GTPase family and Rho‐kinases are associated with ...
Rinako Tanaka, Wenjun Zhu, Taku Nagai, Toshitaka Nabeshima, Kozo Kaibuchi, Norio Ozaki, Hiroaki Ikesue, Hiroyuki Mizoguchi, Kiyofumi Yamada   +8 more
wiley   +1 more source

Neurophysiological responses to stressful motion and anti-motion sickness drugs as mediated by the limbic system [PDF]

Performance is characterized in terms of attention and memory, categorizing extrinsic mechanism mediated by ACTH, norepinephrine and dopamine, and intrinsic mechanisms as cholinergic.
Kohl, R. L., Odell, S.
core   +1 more source

Emerging Treatments for Erectile Dysfunction

Trends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Erectile dysfunction (ED) is a prevalent condition that can significantly affect men's sexual health and quality of life, and for which there are many well‐studied effective treatments. In spite of this, many individuals still seek out alternative therapies.
Resa Magill, Jeff Morrison, Juan Andino, Jasper Bash   +3 more
wiley   +1 more source

Dopaminergic, glutamatergic but not opioidergic mechanisms mediate induction of FOS-like protein by cocaethylene [PDF]

, 1997
Cocaethylene is a psychoactive metabolite formed\ud during the combined consumption of cocaine and ethanol. As\ud this metabolite has many properties in common with cocaine, it is conceivable that cocaethylene administration may induce the activity of ...
DiPirro, Dr. J.M., Horowitz, Dr. J.M., Kristal, Dr. M.B., Torres, Dr. G.   +3 more
core  

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, Volume 121, Issue 6, Page 1530-1540, June 2026.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source