Results 161 to 170 of about 123,317 (298)

RVLM C1 Neurons Innervate Sacral as well as Thoracolumbar Autonomic Preganglionic Neurons in the Rat

open access: yesJournal of Comparative Neurology, Volume 534, Issue 2, February 2026.
Axons expressing the adrenaline‐synthesizing enzyme, phenylethanolamine N‐methyltransferase (PNMT), project widely throughout the spinal cord. Many of these axons are from C1 neurons of the rostral ventrolateral medulla. We confirm that dense arrays of PNMT‐expressing, C1‐derived axons surround thoracolumbar sympathetic preganglionic neurons, many of ...
I. J. Llewellyn‐Smith   +5 more
wiley   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan   +7 more
wiley   +1 more source

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

open access: yesDrug Testing and Analysis, Volume 18, Issue 2, Page 198-206, February 2026.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner   +4 more
wiley   +1 more source

Amphetamine [PDF]

open access: yes, 2020
Helga Peter, Thomas Penzel
openaire   +1 more source

Unexpected Giant Right Coronary Artery Aneurysm Diagnosed by Computed Tomography Angiography in the Emergency Department

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 2, Page 509-515, February 2026.
3D Volume Rendering coronary CTA reconstruction showing a giant thrombosed aneurysm of the proximal right coronary artery ABSTRACT Giant coronary artery aneurysms (GCAA) are usually defined as diameter > 8 mm or > 400% of the adjacent normal segment; they are very rare (reported prevalence ≈0.02%).
Stefano Giusto Picchi   +8 more
wiley   +1 more source

Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 346-363, February 2026.
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander   +4 more
wiley   +1 more source

Duplicate Prescription Patterns in Patients With Substance Use Disorders

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and potentially inappropriate DPs (PIDPs). The study was conducted as a monocentric retrospective cross‐sectional
Johannes Heck   +8 more
wiley   +1 more source

Bifunctional Aziridines from Photochemically Generated FSO2NH2 for SuFEx Diversification of Alkenes

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Photochemically generated FSO2NH2 serves as a safe, practical nitrene precursor for Rh‐catalyzed aziridination of alkenes, granting access to previously inaccessible fluorosulfonyl aziridines. These bifunctional electrophiles merge aziridine ring strain with SuFEx reactivity to provide a modular platform toward aliphatic sulfamoyl fluoride derivatives ...
Avinash Choudhury   +3 more
wiley   +2 more sources

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