Results 61 to 70 of about 122,177 (317)

Bioactivation and Metabolism of Amino Acid MDMA Prodrugs in Zebrafish Embryos, Human Liver S9, Whole Blood, and Microdosed Human Urine

open access: yesDrug Testing and Analysis, EarlyView.
Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg   +6 more
wiley   +1 more source

Co-occurring amphetamine use and associated medical and psychiatric comorbidity among opioid-dependent adults: results from the Clinical Trials Network

open access: yesSubstance Abuse and Rehabilitation, 2011
Daniel J Pilowsky1, Li-Tzy Wu2, Bruce Burchett2, Dan G Blazer2, George E Woody3, Walter Ling41Departments of Epidemiology and Psychiatry, Columbia University, and the New York State Psychiatric Institute, New York City, NY; 2Department of Psychiatry and ...
Blazer DG   +5 more
doaj  

A Highly Sensitive Potentiometric Amphetamine Microsensor Based on All-Solid-State Membrane Using a New Ion-Par Complex, [3,3′-Co(1,2-closo-C2B9H11)2]− C9H13NH+

open access: yesProceedings, 2017
In the present work a highly sensitive ion-selective microelectrode for the detection of amphetamine is presented. For this purpose, a novel ion-par complex based on the metallocarborane, cobalt bis(dicarbollide) anion ([3,3′-Co(1,2-C2B9H11)2]−) coupled ...
J. Gallardo-Gonzalez   +9 more
doaj   +1 more source

Enantioselective Determination of Amphetamine‐Type Stimulants in Environmental Waters Using SPE and CE–MS/MS

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The growing concern over drug abuse, particularly involving amphetamine‐type substances (ATS), has led to their monitoring in environmental waters. These chiral compounds, commonly found in river water and wastewater treatment plant (WWTP) effluents, require analytical methods capable of enantiomeric discrimination, as their enantiomers can ...
Pol Clivillé‐Cabré   +3 more
wiley   +1 more source

Fate of selected drugs in the wastewater treatment plants (WWTPs) for domestic sewage [PDF]

open access: yes, 2019
The wide diffusion of Emerging Organic Micropollutants (EOMs) in the environment is receiving increasing attention due to their potential toxicological effects on living organisms.
Boni, Maria Rosaria   +2 more
core   +1 more source

Differences in patterns of attention deficit/hyperactivity disorder medication use in US children

open access: yesJCPP Advances, EarlyView.
Abstract Background Understanding attention deficit/hyperactivity disorder (ADHD) medication patterns is crucial for optimizing treatment outcomes. There are limited data on racial, ethnic, gender and socioeconomic treatment differences across longitudinal national samples.
Jennie E. Ryan   +4 more
wiley   +1 more source

D-Amphetamine Accelerates Recovery of Consciousness and Respiratory Drive After High-Dose Fentanyl in Rats

open access: yesFrontiers in Pharmacology, 2020
In the United States, fentanyl causes approximately 60,000 drug overdose deaths each year. Fentanyl is also frequently administered as an analgesic in the perioperative setting, where respiratory depression remains a common clinical problem.
Olivia A. Moody   +10 more
doaj   +1 more source

Gender Differences in Smoking Among an Urban Emergency Department Sample. [PDF]

open access: yes, 2019
BackgroundUrban emergency department (ED) patients have elevated smoking and substance use compared with the general population. We analyzed gender differences in smoking among an urban ED sample and assessed the contribution of substance use ...
Alter, Harrison J   +4 more
core  

Improving drug identification in overdose death surveillance by using clinical natural language processing models

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract The rising rate of drug‐related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free‐text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)‐10 classifications.
Arthur J. Funnell   +8 more
wiley   +1 more source

Cannabis and Amphetamine Use Among Adolescents in Five Asian Countries

open access: yesCentral Asian Journal of Global Health, 2017
Introduction: There has been a global increase in illicit drug use among young people. The aim of this study was to estimate the prevalence of lifetime cannabis and amphetamine use, as well as to explore factors associated with substance use among ...
Karl Peltzer, Supa Pengpid
doaj   +1 more source

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