Results 41 to 50 of about 106,948 (272)

Midkine Is a Novel Regulator of Amphetamine-Induced Striatal Gliosis and Cognitive Impairment: Evidence for a Stimulus-Dependent Regulation of Neuroinflammation by Midkine

Mediators of Inflammation, 2016
Midkine (MK) is a cytokine that modulates amphetamine-induced striatal astrogliosis, suggesting a possible role of MK in neuroinflammation induced by amphetamine.
Marta Vicente-Rodríguez, Rosalía Fernández-Calle, Esther Gramage, Carmen Pérez-García, María P. Ramos, Gonzalo Herradón   +5 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Correlation between blood and oral fluid psychoactive drug concentrations and cognitive impairment in driving under the influence of drugs [PDF]

, 2017
The effects of drugs on driving performance should be checked with drug concentration in the brain and at the same time with the evaluation of both the behavioural and neurophysiological effects. The best accessible indicator of this information is the
Busardò, Francesco Paolo, Faro, Alfredo Fabrizio Lo, Graziano, Silvia, Montana, Angelo, Pellegrini, Manuela, Pichini, Simona, Zaami, Simona   +6 more
core   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

Amphetamine-induced psychosis - a separate diagnostic entity or primary psychosis triggered in the vulnerable?

BMC Psychiatry, 2012
Use of amphetamine and methamphetamine is widespread in the general population and common among patients with psychiatric disorders. Amphetamines may induce symptoms of psychosis very similar to those of acute schizophrenia spectrum psychosis.
Bramness Jørgen G, Gundersen Øystein, Guterstam Joar, Rognli Eline, Konstenius Maija, Løberg Else-Marie, Medhus Sigrid, Tanum Lars, Franck Johan   +8 more
doaj   +1 more source

Acute drug effects on habitual and non-habitual responding in crossed high alcohol preferring mice [PDF]

, 2018
RATIONALE: Drug reward plays a central role in acquiring drug-seeking behavior. However, subjects may continue using drugs despite negative consequences because self-administration becomes habitual, and divorced from outcome values. Although a history
Grahame, Nicholas J., Houck, Christa A.
core   +1 more source

Effect of Reaction Time and Temperature on the Impurity Profile of Amphetamine in the Leuckart Method

Drug Testing and Analysis, EarlyView.
This study investigates the effect of the reaction temperature (step 1) and reaction time (step 1 and 2) on the conversion efficiency and impurity profile of amphetamine synthesized via the Leuckart method. Conversion efficiency and impurity profile were assessed using gas chromatography–flame ionization detection (GC–FID) and GC–mass spectrometry (GC ...
Maartje C. M. Verhoeven, Robert C. Huls, Nelly W. van der Stelt, Jelle C. de Koning, Marco van Grol, Ruben F. Kranenburg, Arian C. van Asten, Janneke W. Hulshof   +7 more
wiley   +1 more source

Amphetamine and pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats

BMC Neuroscience, 2008
Background Pseudoephedrine is a drug commonly prescribed as a nasal decongestant and bronchodilator and is also freely available in cold remedies and medications.
Casalotti Stefano O, Tongjaroenbuangam Walaiporn, Ruksee Nootchanart, Govitrapong Piyarat   +3 more
doaj   +1 more source

Amphetamine-Related Fatalities and Altered Brain Chemicals: A Preliminary Investigation Using the Comparative Toxicogenomic Database

Molecules, 2023
Amphetamine is a psychostimulant drug with a high risk of toxicity and death when misused. Abuse of amphetamines is associated with an altered organic profile, which includes omega fatty acids.
Murad Tumayhi, David Banji, Ibrahim Khardali, Otilia J. F. Banji, Saeed Alshahrani, Saad S. Alqahtani, Safiah Muqri, Amal Abdullah, Wedad Sherwani, Ibraheem Attafi   +9 more
doaj   +1 more source

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

Drug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão, T. Rosado, M. Barroso, M. Andraus, E. Gallardo   +4 more
wiley   +1 more source