Direct and long-lasting effects elicited by repeated drug administration on 50-kHz ultrasonic vocalizations are regulated differently: Implications for the study of the affective properties of drugs of abuse [PDF]
, 2013 Several studies suggest that 50-kHz ultrasonic vocalizations (USVs) may indicate a positive affective state in rats, and these vocalizations are increasingly being used to investigate the properties of psychoactive drugs.
FRAU L +3 more
core +1 more source
Optimizing outcomes in ADHD treatment: From clinical targets to novel delivery systems [PDF]
, 2016 Our knowledge and understanding of the underlying neurobiology and symptomatic expression of ADHD has advanced dramatically over the past decade. Associated with these advances has been a similar explosion of new treatment options to individualize ...
Anderson, Richard H +1 more
core +2 more sources
Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice [PDF]
, 2008 Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific dopamine receptor subtypes has not
Atkins +47 more
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Frontiers in Pharmacology, 2017 Rationale: Lisdexamfetamine is a prodrug of D-amphetamine used for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is thought to have a prolonged pharmacokinetic profile compared with oral D-amphetamine, possibly ...
Patrick C. Dolder +5 more
doaj +1 more source
Risk Factors for Opioids and Stimulants Poisoning among Patients Admitted to Khorshid Hospital in Isfahan [PDF]
مجله دانشکده پزشکی اصفهان, 2022 Background: Poisoning by opium and stimulants brings many patients to the poison emergency departments every year. This study planned to determine the risk factors for Opioid and Stimulant poisoning among patients admitted to the Khorshid Hospital ...
Gholamali Dorooshi +5 more
doaj +1 more source
In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999. [PDF]
, 2013 INTRODUCTION: We examined whether [(18)F]LBT-999 ((E)-N-(4-fluorobut-2-enyl)2β-carbomethoxy-3β-(4'-tolyl)nortropane) is an efficient positron emission tomography (PET) tracer for the quantification of the dopamine transporter (DAT) in the healthy rat ...
Chalon, Sylvie +7 more
core +1 more source
Locomotor hyperactivity in 14-3-3Zeta KO mice is associated with dopamine transporter dysfunction [PDF]
, 2013 Dopamine (DA) neurotransmission requires a complex series of enzymatic reactions that are tightly linked to catecholamine exocytosis and receptor interactions on pre- and postsynaptic neurons.
A Abi-Dargham +53 more
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Behavioral and Brain Functions, 2008 Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinical symptoms.
Xu Tong, Sagvolden Terje
doaj +1 more source
Amphetamine, but not methylphenidate, increases ethanol intake in adolescent male, but not in female, rats [PDF]
, 2018 Introduction: There has been an increasing interest in analyzing the interactions between stimulants and ethanol during childhood and adolescence. Stimulants are used to treat attention-deficit hyperactivity disorder (ADHD) in these developmental stages,
Acevedo +77 more
core +1 more source
ADHD medications and drug withdrawal: A pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database. [PDF]
PCN RepPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Ebina T, Iwamoto K, Ikeda M.
europepmc +2 more sources