Results 31 to 40 of about 68,366 (207)

Pharmacology of amphetamine-type designer drugs [PDF]

open access: yes, 2013
In this thesis project, we studied the pharmacology of long-known psychostimulants and of novel amphetamine-type designer drugs in vitro. On the basis of the pharmacological characterization, we focused on the drug effects in humans, investigating the ...
Simmler, Linda
core   +1 more source

Safety of Oral Amphetamine Administered during Positron Emission Tomography Scans in Medically Screened Humans.

open access: yesPLoS ONE, 2015
Changes in endogenous dopamine levels can be detected in humans using positron emission tomography scans by measuring the amount by which a specific D2/3 radioligand is displaced.
Lora D Weidner   +3 more
doaj   +1 more source

Analysis of amphetamines illegally produced in Serbia [PDF]

open access: yesJournal of the Serbian Chemical Society, 2008
Forensic practice in the Republic of Serbia faced the illegal production of amphetamine for the first time in 2003. This paper presents the results of the chemical characterization of 32 batches of amphetamine samples from three separate cases, for the ...
Nevešćanin Marina   +3 more
doaj   +3 more sources

Speeding stroke recovery? A systematic review of amphetamine after stroke [PDF]

open access: yes, 2009
Introduction: The use of drugs to enhance recovery (“rehabilitation pharmacology”) has been assessed. Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke.
Nikola Sprigg   +3 more
core   +1 more source

Use of Lisdexamfetamine or Amphetamine? Interpretation of Chiral Amphetamine Analyses

open access: yes, 2022
Amphetamine is frequently detected in forensic toxicological cases. Differentiating between the two isomers of amphetamine (d-amphetamine and l-amphetamine) and determining their relative proportion are fundamental to correctly interpret the results of ...
Jönsson, Anna K,   +4 more
core   +1 more source

l-Amphetamine improves poor sustained attention while d-amphetamine reduces overactivity and impulsiveness as well as improves sustained attention in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)

open access: yesBehavioral and Brain Functions, 2008
Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinical symptoms.
Xu Tong, Sagvolden Terje
doaj   +1 more source

Glycogen synthase kinase-3β inhibition in the medial prefrontal cortex mediates paradoxical amphetamine action in a mouse model of ADHD

open access: yesFrontiers in Behavioral Neuroscience, 2015
Psychostimulants show therapeutic efficacy in the treatment of attention-deficit hyperactivity disorder (ADHD). It is generally assumed that they ameliorate ADHD symptoms via interfering with monoaminergic signaling.
Yi-Chun eYen   +6 more
doaj   +1 more source

Midkine Is a Novel Regulator of Amphetamine-Induced Striatal Gliosis and Cognitive Impairment: Evidence for a Stimulus-Dependent Regulation of Neuroinflammation by Midkine

open access: yesMediators of Inflammation, 2016
Midkine (MK) is a cytokine that modulates amphetamine-induced striatal astrogliosis, suggesting a possible role of MK in neuroinflammation induced by amphetamine.
Marta Vicente-Rodríguez   +5 more
doaj   +1 more source

Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333) [PDF]

open access: yes, 2007
Amphetamine enhances recovery after experimental ischaemia and has shown promise in small clinical trials when combined with motor or sensory stimulation.
Sprigg, N   +12 more
core   +1 more source

Amphetamine Use Revealing Hypertrophic Cardiomyopathy in a Young Patient. [PDF]

open access: yes, 2022
Adrenergic overstimulation in long term can lead to a hyperdynamic myocardium and give rise to hypertrophy and ultimately to heart failure. Amphetamine use is a common cause of neurohormonal activation, which gives rise to such adverse cardiovascular ...
Stamou, Konstantinos   +13 more
core   +2 more sources

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