The Evolution of Medications for Obesity Management
ABSTRACT This narrative review provides an overview of progress in the development of obesity medications, including a synthesis of data describing the efficacy and safety of currently available agents and emerging therapeutic options. Historically, many obesity medications have been withdrawn from the market due to safety concerns.
Jaskirath Gill, Priya Sumithran
wiley +1 more source
Encephalopathy following subcutaneous administration of Brixadi® extended-release buprenorphine. [PDF]
Seltzer J +7 more
europepmc +1 more source
ABSTRACT Introduction Global awareness to chemsex, a specific form of sexualized psychoactive substance (“chems”) use among gay, bisexual and other men who have sex with men (gbMSM), is increasing. We aimed to assess prevalence, patterns and implications of “chems” use on chemsex‐related outcomes.
Bashkim Jaha +14 more
wiley +1 more source
Non-suicidal Self-Injury in the Context of Psoriasis, Post-traumatic Stress Disorder, and Acute Polysubstance Intoxication. [PDF]
Csete I, Sackett A, Meresh E.
europepmc +1 more source
Assessing mortality risk in narcolepsy: Evidence from population studies
Abstract Narcolepsy is a chronic neurologic sleep disorder associated with excessive daytime sleepiness, cataplexy, and a higher prevalence of cardiovascular and psychiatric comorbidities. While these factors may predispose individuals to adverse events, observational studies evaluating mortality in narcolepsy have yielded inconsistent results.
Nawris Alhassan +2 more
wiley +1 more source
Complete recovery of thrombotic microangiopathy with severe acute kidney injury due to intravenous use of modified release oxycodone. [PDF]
Ezeakile M, Zirapury T.
europepmc +1 more source
Hepatitis C Micro‐Elimination in a Deprived Coastal Town: Lessons From Blackpool
By making hepatitis C virus (HCV) testing a routine part of care, Blackpool's drug and alcohol services dramatically improved HCV diagnosis and treatment and achieved HCV micro‐elimination. Continued commitment to this new way of working will be essential to sustain these gains.
Sarah E. Blagden +2 more
wiley +1 more source
Predictors of clinically diagnosed premature ventricular complexes in acute care settings: a cohort study. [PDF]
Noubiap JJ +6 more
europepmc +1 more source
Evaluation of illicit drug contaminants in seized cannabis in Arizona and California, 2023–2024
Abstract Despite public health concerns, fentanyl, cocaine, and other illicit drug contaminants remain largely understudied in unregulated cannabis. Here, we developed an analytical method to quantify a panel of common illicit drugs in cannabis and tested the law enforcement seizures in Arizona and California in evaluation of the illicit drug ...
Beckner Andersano +3 more
wiley +1 more source
A call for action: Closing the evidence gap in management of stimulant‐induced psychosis
Abstract Background Stimulant‐induced psychosis (StIP) is emerging as one of most pressing health challenges. Over the past two decades, stimulant‐related harms and psychiatric care demands have risen sharply. Individuals with StIP often present with severe agitation and high suicide risk, and up to half progress to chronic psychotic illness within two
Anne Bouthillier +3 more
wiley +1 more source

