Results 11 to 20 of about 476 (110)

DNA in Amphibian and Reptile Venom Permits Access to Genomes without Specimen Sacrifice [PDF]

Genomics Insights, 2008
Amphibian defensive skin secretions and reptile venoms are rich sources of bioactive peptides with potential pharmacological/pharmaceutical applications. As amphibian and reptile populations are in rapid global decline, our research group has been developing analytical methods that permit generation of robust molecular data from non-invasive skin ...
Kwok, Hang Fai, Chen, Tianbao, Ivanyi, Craig, Shaw, Christopher   +3 more
openaire   +1 more source

Venom-based medicines: Advancing drug discovery with reptile and amphibian venom peptides [PDF]

The Biochemist, 2009
Amphibian skin has long been known by humans to possess intriguing biological properties and scientific examination of these secretions has revealed that their components possess a range of medical properties. In Japan and China, toad venom has been used as an expectorant, anti-haemorrhagic, diuretic and cardiac stimulant, and some peptides in the ...
openaire   +1 more source

Coagulotoxicity of Bothrops (Lancehead Pit-Vipers) Venoms from Brazil: Differential Biochemistry and Antivenom Efficacy Resulting from Prey-Driven Venom Variation

Toxins, 2018
Lancehead pit-vipers (Bothrops genus) are an extremely diverse and medically important group responsible for the greatest number of snakebite envenomations and deaths in South America.
Leijiane F. Sousa, Christina N. Zdenek, James S. Dobson, Bianca op den Brouw, Francisco C. P. Coimbra, Amber Gillett, Tiago H. M. Del-Rei, Hipócrates de M. Chalkidis, Sávio Sant’Anna, Marisa M. Teixeira-da-Rocha, Kathleen Grego, Silvia R. Travaglia Cardoso, Ana M. Moura da Silva, Bryan G. Fry   +13 more
doaj   +1 more source

Antileishmanial and antitrypanosomal activity of the cutaneous secretion of Siphonops annulatus

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background Among the tropical parasitic diseases, those caused by protozoans are considered a challenge to public health, being represented by leishmaniasis and Chagas disease.
Erika Gracielle Pinto, Marta Maria Antoniazzi, Carlos Jared, and Andre Gustavo Tempone   +3 more
doaj   +1 more source

Ranakinestatin-PPF from the Skin Secretion of the Fukien Gold-Striped Pond Frog, Pelophylax plancyi fukienensis: A Prototype of a Novel Class of Bradykinin B2 Receptor Antagonist Peptide from Ranid Frogs

The Scientific World Journal, 2014
The defensive skin secretions of many amphibians are a rich source of bradykinins and bradykinin-related peptides (BRPs). Members of this peptide group are also common components of reptile and arthropod venoms due to their multiple biological functions
Jie Ma, Yu Luo, Lilin Ge, Lei Wang, Mei Zhou, Yingqi Zhang, Jinao Duan, Tianbao Chen, Chris Shaw   +8 more
doaj   +1 more source

Deadly cures: Unlocking anticancer potential of reptile, amphibian, and arthropod venoms through molecular innovation and nanotechnology

Next Nanotechnology
Venoms from reptiles, amphibians, and arthropods represent a rich source of bioactive molecules with promising anticancer potential. Recent studies have highlighted the selective cytotoxicity of venom components including snake phospholipase A2 enzymes ...
Pranav Ragavendra Shankar, Apsara Unni
doaj   +1 more source

Much more than their fangs: Macroscopic anatomy of the brain of Bothrops moojeni Hoge 1966 (Squamata, Serpentes, Viperidae)

The Anatomical Record, EarlyView.
Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo, Júlio César Costa de Souza, Angele Martins   +2 more
wiley   +1 more source

Early stages of tooth development in the harbor porpoise Phocoena phocoena

The Anatomical Record, EarlyView.
Abstract Here we describe the stages of tooth development in toothed whales on the basis of the harbor porpoise (Phocoena phocoena). The aim of the study was to find out whether these stages are identical to those of other mammals analyzed so far although toothed whales are homodont and monophyodont.
Lasse M. Mathes, Lennart Müller‐Thomsen, Stefan Huggenberger   +2 more
wiley   +1 more source

The impacts of biological invasions

Biological Reviews, EarlyView.
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock, Teun Everts, Neil Angelo S. Abreo, Jamie Bojko, Victor Deklerck, James W. E. Dickey, Ana Clara S. Franco, Emili García‐Berthou, Stelios Katsanevakis, Natalia I. Kirichenko, Stefano Mammola, Martin A. Nuñez, Ben Parker, Riccardo Scalera, Ismael Soto, Diederik Strubbe, Ali Serhan Tarkan, Lorenzo Vilizzi, Tim Adriaens, Paride Balzani, Dagmara Błońska, Elizabeta Briski, Rein Brys, Amy L. Burgess, James E. Byers, Carlos Cano‐Barbacil, Giuseppe Castaldelli, Jaimie T.A. Dick, Victoria Dominguez Almela, Romina D. Dimarco, Margarita Florencio, Antonín Kouba, Melina Kourantidou, Irmak Kurtul, Irene Martín‐Forés, Olivier Morissette, Julian D. Olden, Bruno E. Soares, Jakub Truszkowski, Hugo Verreycken, Marc Kenis, Ronaldo Sousa, J. Robert Britton   +42 more
wiley   +1 more source

Ecology and evolution of pyrazines in insects

Biological Reviews, EarlyView.
ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk, Niklas Wahlberg, Johanna Mappes   +2 more
wiley   +1 more source