Results 21 to 30 of about 12,846 (195)

Nanotherapeutics Containing Lithocholic Acid-Based Amphiphilic Scorpion-Like Macromolecules Reduce In Vitro Inflammation in Macrophages: Implications for Atherosclerosis

Nanomaterials, 2018
Previously-designed amphiphilic scorpion-like macromolecule (AScM) nanoparticles (NPs) showed elevated potency to counteract oxidized low-density lipoprotein (oxLDL) uptake in atherosclerotic macrophages, but failed to ameliorate oxLDL-induced ...
Alysha Moretti, Qi Li, Rebecca Chmielowski, Laurie B. Joseph, Prabhas V. Moghe, Kathryn E. Uhrich   +5 more
doaj   +1 more source

pH-Sensitive Dendrimersomes of Hybrid Triazine-Carbosilane Dendritic Amphiphiles-Smart Vehicles for Drug Delivery

Nanomaterials, 2020
Supramolecular constructions of amphiphilic dendritic molecules are promising vehicles for anti-cancer drug delivery due to the flexibility of their architecture, high drug loading capacity and avoiding off-target effects of a drug.
Evgeny Apartsin, Nadezhda Knauer, Valeria Arkhipova, Ekaterina Pashkina, Alina Aktanova, Julia Poletaeva, Javier Sánchez-Nieves, Francisco Javier de la Mata, Rafael Gómez   +8 more
doaj   +1 more source

Peptide based amphiphiles [PDF]

Chem. Soc. Rev., 2004
Contains fulltext : 59199.pdf (Publisher’s version ) (Open Access)
Lowik, D.W.P.M., Hest, J.C.M. van
openaire   +4 more sources

Molecular Dynamic Simulation Search for Possible Amphiphilic Drug Discovery for Covid-19

Molecules, 2021
To determine whether quaternary ammonium (k21) binds to Severe Acute Respiratory Syndrome–Coronavirus 2 (SARS-CoV-2) spike protein via computational molecular docking simulations, the crystal structure of the SARS-CoV-2 spike receptor-binding domain ...
Umer Daood, Divya Gopinath, Malikarjuna Rao Pichika, Kit-Kay Mak, Liang Lin Seow   +4 more
doaj   +1 more source

The intriguing dose-dependent effect of selected amphiphilic compounds on insulin amyloid aggregation: Focus on a cholesterol-based detergent, Chobimalt

Frontiers in Molecular Biosciences, 2022
The amyloidogenic self-assembly of many peptides and proteins largely depends on external conditions. Among amyloid-prone proteins, insulin attracts attention because of its physiological and therapeutic importance.
Katarina Siposova, Viktor I. Petrenko, Viktor I. Petrenko, Ivana Garcarova, Dagmar Sedlakova, László Almásy, Olena A. Kyzyma, Olena A. Kyzyma, Manfred Kriechbaum, Andrey Musatov   +9 more
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Detergents

Oléagineux, Corps gras, Lipides, 2001
Surfactants are amphiphile molecules. They can be anionic, cationic, nonionic or amphoteric. They are among the main ingredients encountered in detergents and personal care products.
Ho Tan Tai Louis, Nardello-Rataj Véronique   +1 more
doaj   +1 more source

Accurate and sensitive probing of onset of micellization based on absolute aggregation‐caused quenching effect

Aggregate, 2022
Probing the onset of micellization, or determining the critical micelle concentration (CMC), is of crucial importance while remains to be challenged by growing demand for extraordinary sensitivity and accuracy.
Haisheng He, Chang Liu, Jiang Ming, Yongjiu Lv, Jianping Qi, Yi Lu, Xiaochun Dong, Weili Zhao, Wei Wu   +8 more
doaj   +1 more source

Antifungal amphiphilic aminoglycosides [PDF]

MedChemComm, 2014
A C8 alkyl chain at the O-4′′ position of kanamycin B transforms this aminoglycoside into an amphiphilic broad spectrum antifungal compound.
Chang, Cheng-Wei Tom, Takemoto, Jon Y.
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Study of in vitro poorly soluble drug solubility into fasted state simulated intestinal fluid reflective of in vivo gastrointestinal variability

British Journal of Pharmacy, 2023
Solubility and dynamic light scattering (DLS) studies of three poorly soluble drugs(naproxen, indomethacin and phenytoin) in simulated intestinal fluid (SIF) were carried out in order to calculate the number of drug molecules per micelle based on the ...
Zoe McKinnon, Hannah Batchelor , Ibrahim Khadra, Gavin Halbert   +3 more
doaj   +1 more source

Aggregation of p-Sulfonatocalixarene-Based Amphiphiles and Supra-Amphiphiles [PDF]

International Journal of Molecular Sciences, 2013
p-Sulfonatocalixarenes are a special class of water soluble macrocyclic molecules made of 4-hydroxybenzenesulfonate units linked by methylene bridges. One of the main features of these compounds relies on their ability to form inclusion complexes with cationic and neutral species.
Basilio, Nuno, Francisco, Vitor, Garcia-Rio, Luis   +2 more
openaire   +2 more sources