Results 141 to 150 of about 13,097,347 (378)

Self-aggregated nanoparticles based on amphiphilic poly(lactic acid)-grafted-chitosan copolymer for ocular delivery of amphotericin B

International Journal of Nanomedicine, 2013
Background The purpose of this study was to develop a self-aggregated nanoparticulate vehicle using an amphiphilic poly(lactic acid)-grafted-chitosan (PLA-g-CS) copolymer and to evaluate its potential for ocular delivery of amphotericin B.
Wenjun Zhou, Yuanyuan Wang, Jiuying Jian, Shengfang Song   +3 more
semanticscholar   +1 more source

Green Propolis Extract‐Mediated Synthesis of Biogenic Silver Nanoparticles: In Vitro Antileishmanial and Antibacterial Activities, Cytotoxicity and Ex Vivo Irritation Testing

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study describes the green synthesis, characterization, and biological evaluation of silver nanoparticles (AgNPs) obtained from green propolis (AgNPs‐PRO). Before nanoparticles synthesis, a hydroethanolic green propolis extract (GPE) was obtained through ultrasound‐assisted extraction and characterized by high‐performance liquid ...
Erica Tirzah S. Lima, Victoria L. S. Santos, Wanessa J. S. Mota, Frederico S. Martins, Ricardo L. C. de Albuquerque‐Junior, André L. S. Santos, Simone S. C. Oliveira, Jéssica A. de Lima, Adriana de Jesus Santos, Cochiran P. dos Santos, Sona Jain, Eliana B. Souto, Juliana C. Cardoso, Patrícia Severino   +13 more
wiley   +1 more source

Synergistic effect of terbinafine and amphotericin B in killing Fonsecaea nubica in vitro and in vivo

Revista do Instituto de Medicina Tropical de São Paulo
Chromoblastomycosis is a chronic fungal infection. Itraconazole and terbinafine are the most recommended antifungal drugs for chromoblastomycosis, while amphotericin B is not usually recommended.
Jing Zhang, Xiaoyan Wu, Meirong Li, Jiamin Huang, Songchao Yin, Huaiqiu Huang, Chun Lu, Liyan Xi   +7 more
doaj   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, EarlyView.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives

Chemistry &Biodiversity, EarlyView.
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos, Marie Demonceaux, Lucia Emanueli Schimith, Marine Goux, Claude Solleux, Ana Luiza Muccillo‐Baisch, Bruno Dutra Arbo, Corinne Andre‐Miral, Mariana Appel Hort   +8 more
wiley   +1 more source

Protective and antifungal properties of Nanodisk-Amphotericin B over commercially available Amphotericin B

World Journal of Otorhinolaryngology-Head and Neck Surgery, 2017
Objective: Amphotericin B (AMB), a potent antifungal agent, has been employed as topical and systemic therapy for sinonasal fungal infections. A novel formulation of nanodisc (ND) containing super aggregated AMB (ND-AMB) for the treatment of fungal ...
Do-Yeon Cho, Kyle J. Hoffman, Gobind S. Gill, Dong-Jin Lim, Daniel Skinner, Calvin Mackey, Steven M. Rowe, Bradford A. Woodworth   +7 more
doaj  

Persistence of amphotericin B in the bagina. Estimation by a novel sampling method. [PDF]

, 1968
R. D. Shannon, A E Tinkler, Alan J. Hedges   +2 more
openalex   +1 more source

A Prospective Longitudinal Study of the Clinical Outcomes from Cryptococcal Meningitis following Treatment Induction with 800 mg Oral Fluconazole in Blantyre, Malawi [PDF]

, 2013
Introduction: Cryptococcal meningitis is the most common neurological infection in HIV infected patients in Sub Saharan Africa, where gold standard treatment with intravenous amphotericin B and 5 flucytosine is often unavailable or difficult to ...
A Loyse, AT Makadzange, BJ Park, Brigitte Denis, C Bekondi, Camilla Rothe, CF Schaars, CK Muzoora, David G. Lalloo, Derek J. Sloan, DK Lewis, E Milefchik, H Mayanja-Kizza, HM Hodkinson, JC Nussbaum, Jean Chikafa, JG Hakim, JN Day, JN Jarvis, JN Jarvis, Joep J. van Oosterhout, JR Perfect, K McCarthy, KA Johansson, Laboratory Evaluation and Standards, Mavuto Mukaka, N Longley, Nicholas A. Feasey, P Mwaba, Patrick Goodson, PG Pappas, PR Kisenge, Robert J. Wilkinson, Robert S. Heyderman, RS Heyderman, SB Gordon, T Bicanic, T Bicanic, T Heikinheimo, Theresa Allain, TJ Allain, Tom Harrison   +41 more
core   +3 more sources

It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug

Front. Microbio., 2012
“Amphotericin B acts through pore formation at the cell membrane after binding to ergosterol” is an accepted dogma about the action mechanism of this antifungal, and this sentence is widely found in the literature.
A. Mesa-Arango, L. Scorzoni, Ó. Zaragoza   +2 more
semanticscholar   +1 more source

Effects of Amphotericin B In Vitro on Perfect and Imperfect Strains of Allescheria boydii [PDF]

, 1967
H. S. Nielsen
openalex   +1 more source