Results 231 to 240 of about 95,889 (290)

Mitomycin C Induces Autophagy in Human Tracheal Fibroblasts and Suppresses Their Growth

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 5, October 2025.
Mitomycin C (MMC) selectively inhibits the proliferation of human tracheal fibroblasts (hTF) more effectively than human tracheal epithelial cells (hTEC), with hTF showing a dose‐ and time‐dependent sensitivity to MMC treatment. Additionally, MMC induces autophagy in hTF, as evidenced by increased expression of autophagy markers, while suppressing cell
Jeong‐Mi Kim   +5 more
wiley   +1 more source

Evaluation of the Antifungal Properties of Azomethine‐Pyrazole Derivatives from a Structural Perspective

open access: yesChemistryOpen, Volume 14, Issue 10, October 2025.
A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo   +8 more
wiley   +1 more source

Genome analyses of amphotericin B-susceptible and -resistant strains of <i>Leishmania</i> (<i>Mundinia</i>) <i>martiniquensis</i> reveal variations potentially related to amphotericin B resistance. [PDF]

open access: yesCurr Res Parasitol Vector Borne Dis
Jariyapan N   +11 more
europepmc   +1 more source

Bezlotoxumab as Treatment for Recurrent/Chronic Clostridioides difficile Infection in Pediatric Stem Cell Transplant Recipients: A Multi‐Institutional Experience

open access: yesPediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Clostridioides difficile infection (CDI) represents a significant health risk to pediatric stem cell transplant (SCT) patients. In these patients, recurrent CDI is common, requiring prolonged antibiotic usage and increased hospitalization. Bezlotoxumab, a monoclonal antibody that targets the toxin responsible for CDI, has demonstrated efficacy
Aaron E. Fan   +8 more
wiley   +1 more source

In Vitro Efficacy and Toxicity Assessment of an Amphotericin B Gel for the Treatment of Cutaneous Leishmaniasis. [PDF]

open access: yesPharmaceuticals (Basel)
Sosa L   +7 more
europepmc   +1 more source

Utility of BioFire FilmArray Pneumonia Panel Plus in a High‐Risk Cohort: Children Post Allogeneic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Introduction Pulmonary complications due to infection contribute significantly to post‐haematopoietic stem cell transplant (HCT) morbidity and mortality. Standard microbiological investigations, when performed on bronchoalveolar lavage (BAL) fluid, can take days to weeks to confirm a diagnosis.
Hannah Walker   +8 more
wiley   +1 more source

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