Results 181 to 190 of about 348,393 (352)

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Substituted ampicillins [PDF]

Journal of Antimicrobial Chemotherapy, 1977
openaire   +2 more sources

A Promising Antibacterial Inhibition of Propolis Extracts Against Carbapenem‐Resistant Bacteria Isolated From Clinical Samples

Chemistry &Biodiversity, EarlyView.
ABSTRACT The increasing inadequacy of antibiotics against multidrug‐resistant pathogens is a growing concern. In this study, the antibacterial activity of propolis extracts with different phenolic profiles against carbapenem‐resistant clinical isolates was investigated.
Ülkü Zeynep Esertaş, Neşe Inal, Zehra Can, Sevgi Kolaylı   +3 more
wiley   +1 more source

Preparation of doped Mn, N-CDs and their application in the detection of ampicillin. [PDF]

Sci Rep
Ye M, Zhang Y, Ding P, Meng L.
europepmc   +1 more source

Tandem Mass Spectrometry and Bio‐Guided Isolation of Secondary Metabolites With Antiplasmodial Activity From Dalbergia miscolobium Bark

Chemistry &Biodiversity, EarlyView.
ABSTRACT Strategies have been employed to address antimalarial drug resistance, including the exploration of new therapeutic targets. In this study, the stem bark of Dalbergia miscolobium was investigated using in vitro assays against Plasmodium falciparum and pyruvate kinase II (PyrKII), an essential enzyme for parasite development.
Thais Bertolino Vieira Dantas, Igor M. R. Moura, Romário Pereira da Costa, Guilherme Eduardo de Souza, Richele Priscila Severino, Hélder Nagai Consolaro, Luis Felipe de Oliveira, Vinicius Bonatto, Quezia Bezerra Cass, Rafael V. C. Guido, Lorena Ramos Freitas de Sousa   +10 more
wiley   +1 more source

Antibiotic Use in Livestock: A Driver of Resistance in Africa and the Path to Safer Alternatives. [PDF]

Microbiologyopen
Alabi MA, Chenia HY, Lin J.
europepmc   +1 more source

Synthesis, evaluation, and structural characterization of antioxidant diorganotin(IV) Complexes derived from ampicillin: a comprehensive study

Rafid Ryyis Arraq, Hadeer Jasem, Angham G. Hadi G. Hadi   +2 more
openalex   +1 more source

ampC beta-lactamase hyperproduction in Escherichia coli: natural ampicillin resistance generated by horizontal chromosomal DNA transfer from Shigella.

, 1983
Olof Olsson, Sven Bergström, Frederik P. Lindberg, Staffan Normark   +3 more
openalex   +2 more sources

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Clinical impact of prophylactic antibiotics in kidney transplantation: A retrospective observational cohort study with historical comparison. [PDF]

PLoS One
Lee SA, Kim JM, Kwon HE, Ko Y, Jung JH, Shin S, Kim YH, Kim SH, Kwon H.   +8 more
europepmc   +1 more source