Results 181 to 190 of about 405,864 (350)

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

iMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng, Huiying Liu, Sizhe Chen, Jianhui Gu, Sisi Cai, Xiang Liu, Raphaela I. Lau, Yao Zhang, Sunjae Lee, Xiaoyan Wang, Kewei Fan, Xiaole Yin, Hein Min Tun, Renyou Gan, Haichong Wu, Qi Su   +15 more
wiley   +1 more source

Antibiotic resistance in odontogenic infections: A systematic review of current evidence and implications for guideline-based therapy. [PDF]

Clin Oral Investig
Schmid AI, Werkmeister R, Al-Nawas B, Heider J.   +3 more
europepmc   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Reduced ROS-associated prophage induction in a lepA mutant contributes to increased fluoroquinolone persistence in Salmonella Typhimurium. [PDF]

Sci Rep
Braetz S, Karp M, Nerlich A, Fulde M.
europepmc   +1 more source

High-Dose Ampicillin-Sulbactam Combinations Combat Polymyxin-Resistant Acinetobacter baumannii in a Hollow-Fiber Infection Model

Antimicrobial Agents and Chemotherapy, 2017
Justin R. Lenhard, Nicholas M. Smith, Z. Bulman, Xun Tao, V. Thamlikitkul, B. Shin, R. Nation, Jian Li, J. Bulitta, Brian T. Tsuji   +9 more
semanticscholar   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

<i>Gazania rigens</i> (L.) gaertn leaf extract-inspired innovative synthesis of silver nanoparticles and promising applications as antibacterial and cytotoxic agents. [PDF]

Front Chem
Mohammed AE, Aldahasi RM, Aldraiwiesh HO, Rahman I, Alhammadi MM, Albadari N, Bin Break MK, Alghamdi SS, Aabed K.   +8 more
europepmc   +1 more source

Augmented antibacterial activity of ampicillin with silver nanoparticles against methicillin-resistant Staphylococcus aureus (MRSA)

Journal of antibiotics (Tokyo. 1968), 2018
P. Surwade, Christopher Ghildyal, Chase Weikel, T. Luxton, Derek M Peloquin, Xin Fan, Vishal Shah   +6 more
semanticscholar   +1 more source

Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative

Journal of Hospital Medicine, EarlyView.
Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski, Karen Howard, Hannah Imlay, Chaorong Wu, Christy L. Hopkins, Valerie M. Vaughn, Emily S. Spivak   +6 more
wiley   +1 more source

Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in <i>Caulobacter crescentus</i>. [PDF]

Elife
Richter P, Merz A, Biboy J, Paczia N, Glatter T, Ng J, Vollmer W, Thanbichler M.   +7 more
europepmc   +1 more source