Results 181 to 190 of about 232,371 (305)

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

Cefazolin as an alternative in patients with a history of penicillin or β-lactam antibiotic allergy: A case overview. [PDF]

Allergol Select
Kreft B, Wohlrab J, Sunderkötter C.
europepmc   +1 more source

Miniaturized Droplet‐Based Adaptation of the Ames Test for High‐Throughput Mutagenicity Assessment

Journal of Applied Toxicology, EarlyView.
ABSTRACT This work presents the first demonstration of a tube‐based droplet microfluidic implementation of the Ames test, bridging single‐droplet resolution with regulatory genotoxicity testing. The Ames test is a cornerstone assay for detecting mutagenicity, but conventional plate‐ and well‐based formats suffer from high reagent consumption, low ...
Jialan Cao, Bayan Nasr, J. Michael Köhler, Sebastian Buchinger   +3 more
wiley   +1 more source

Progressive Cellularization of Blastoderm and Extraembryonic Tissue Formation in the Ant Camponotus floridanus

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Illustration of the process of cellularization in Camponotus floridanus (top row) compared to Drosophila melanogaster (bottom row). Progressive direct formation of differentiating blastoderm mode is depicted using hexagons that represent energids (without borders) and cells (with borders). Colors of nuclei represent different cell types.
Nihan Sultan Milat, Murat Pekmez, Ab. Matteen Rafiqi   +2 more
wiley   +1 more source

Comparison of Ceftobiprole Versus Ampicillin-ceftriaxone Antibacterial Activity Against Borderline-penicillin-resistant Ampicillin-susceptible and Vancomycin-resistant Enterococcus Faecalis

Background: Enterococcus faecalis endocarditis mortality rates exceed 30% despite the use of first-line ampicillin plus ceftriaxone therapy. We identified decreased ampicillin-ceftriaxone activity against borderline-penicillin-resistant, ampicillin ...
Khan, Ifra, Li, Jingyi
core  

Duration of early empirical antibiotic exposure in very low birth weight infants with suspected early-onset sepsis and associated factors: a retrospective cohort study. [PDF]

Front Pediatr
Morales-Bentacourt C, Canales-Siguero MD, Fernández-Gaitán M, Montealegre-Pomar A, Bergon-Sedín E, De Alba-Romero C, Pallás Alonso CR, Moral-Pumarega MT.   +7 more
europepmc   +1 more source

Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative

Journal of Hospital Medicine, EarlyView.
Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski, Karen Howard, Hannah Imlay, Chaorong Wu, Christy L. Hopkins, Valerie M. Vaughn, Emily S. Spivak   +6 more
wiley   +1 more source

Modulating Micrococcal Nuclease-Triggered Antibiotic Releases for One-Stage Revisions of <i>Staphylococcus aureus</i>-Infected Prostheses. [PDF]

ACS Infect Dis
Skelly JD, Chen F, Song J.
europepmc   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

The impact of an ex vivo paediatric renal replacement therapy circuit on antimicrobial concentrations. [PDF]

J Antimicrob Chemother
Cree ML, Abdul-Aziz MH, Wallis SC, Won H, Sumi CD, Marjanovic D, Ordonez JL, Schlapbach LJ, Roberts JA.   +8 more
europepmc   +1 more source