Results 1 to 10 of about 182,488 (255)

An Unusual Case of Ototoxicity with Use of Oral Vancomycin

Case Reports in Infectious Diseases, 2018
Introduction. Systemic absorption of oral vancomycin is poor due to the size of the molecule and its pharmacokinetics. It has an elimination half life of 5–11 hours in patients with normal renal function.
Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh   +4 more
doaj   +1 more source

Vancomycin-resistant Staphylococcus aureus (VRSA) can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability.

PLoS Pathogens
Vancomycin has proven remarkably durable to resistance evolution by Staphylococcus aureus despite widespread treatment with vancomycin in the clinic. Only 16 cases of vancomycin-resistant S. aureus (VRSA) have been documented in the United States.
Samuel E Blechman, Erik S Wright
doaj   +1 more source

Necessity of vancomycin trough concentrations to manage uncomplicated acute bacterial skin and skin structure infections: a laboratory stewardship analysis

Drugs in Context, 2023
Background: Recent recommendations by the American Society of Health System Pharmacists and Infectious Disease Society of America have provided guidance regarding vancomycin dosing and monitoring in serious infections (including methicillin-resistant ...
Andrew Merker, Kartik Anne, Justin Rayyan, Milena Murray   +3 more
doaj   +1 more source

Vancomycin Removal During High-Volume Peritoneal Dialysis in Acute Kidney Injury Patients: A Prospective Cohort Clinical Study

Kidney International Reports, 2019
Introduction: Vancomycin pharmacokinetic data in patients with acute kidney injury (AKI) on high-volume peritoneal dialysis (HVPD) are lacking. The aims were to study the pharmacokinetics of i.v.
Daniela Ponce, Welder Zamoner, Fernanda Moreira Freitas, André Balbi, Linda Awdishu   +4 more
doaj   +1 more source

Effect of an intervention targeting inappropriate continued empirical parenteral vancomycin use: a quasi-experimental study in a region of high MRSA prevalence

BMC Infectious Diseases, 2018
Background Despite vancomycin use is a major risk factor for the emergence of vancomycin resistance, it is frequently inappropriately prescribed, especially as empirical treatment.
Pyoeng Gyun Choe, Hei Lim Koo, Doran Yoon, Ji Yun Bae, Eunyoung Lee, Joo-Hee Hwang, Kyoung-Ho Song, Wan Beom Park, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Sang Won Park, Myoung-don Oh, Nam Joong Kim   +13 more
doaj   +1 more source

Predicted Vancomycin Dosage Requirement in Patients With Hematological Malignancies and Dosage Dynamic Adjustment

Frontiers in Pharmacology, 2022
Purpose: The purpose of this study was 1) to predict the requisite vancomycin daily dose (Dvan) used in the target patients suffering from both bacterial infection and hematological malignancies and 2) to construct a vancomycin-dose-graphical tool to ...
Xiangqing Song, Yi Wu
doaj   +1 more source

Renal Protective Effect of Sulbutiamine, Thiamine, Riboflavin and their Combinations on Vancomycin-Induced Acute Renal Failure in Male Rats

Iraqi Journal of Pharmaceutical Sciences
Background: The main mechanisms thought to be involved in the pathophysiology of acute renal failure with vancomycin treatment are oxidative stress, inflammation and apoptosis.  In this study we evaluated the potential effects of sulbutiamine, thiamine,
Dayan K. Jabbar , Ghaith A. Jasim, Muthana I. Al-Ezzi   +2 more
doaj   +1 more source

Laboratory correlation between vancomycin levels and serum creatinine in the nephrotoxicity of vancomycin

Cogent Medicine, 2016
Reports about relationship on renal function and vancomycin exposure are conflicted and limited. Goals: To identify if high serum vancomycin levels precede changes in serum creatinine or if it is secondary to reduced glomerular filtration and to analyze ...
Luiza K.R.P. Araújo, Yule A. Ueno, Thais Gentil, Emília M.D. Soeiro, Isac Castro, Sandra M. Laranja, Benedito Jorge Pereira   +6 more
doaj   +1 more source

Phenotypic and molecular characterisation of Staphylococcus aureus with reduced vancomycin susceptibility derivated in vitro

Open Medicine, 2018
Vancomycin has been the primary agent used to treat serious Methicillin-resistant Staphylococcus aureus (MRSA) infection for many years. However, the rise of MRSA infection rates and the extensive use of vancomycin have led to the emergence of reduced ...
Xu Jia, Pang Long, Ma Xiao Xue, Hu Jian, Tian Yuan, Yang Ya Li, Sun Dan Dan   +6 more
doaj   +1 more source

Immunoglobulin E-mediated hypersensitivity reaction after intraperitoneal administration of vancomycin

Kidney Research and Clinical Practice, 2015
Intraperitoneal (IP) vancomycin is widely used to treat Gram-positive peritonitis associated with peritoneal dialysis. There have been two cases of red man syndrome (RMS), a vancomycin-specific nonimmunologic reaction, associated with IP vancomycin ...
Mun-Ju Hwang, Jun-Young Do, Eun-Woo Choi, Joon-Hyuk Seo, Yoon-Jung Nam, Kyung-Woo Yoon, Jong-Won Park, Kyu-Hyang Cho, Seok-Hui Kang, Hyun-Jung Jin   +9 more
doaj   +1 more source