Results 1 to 10 of about 165,040 (305)

The Association of the mazEF Toxin-antitoxin System and Vancomycin Resistance in Clinical Isolates of Vancomycin Resistant Enterococcus faecalis

, 2022
Vancomycin resistant enterococci are challenging bacteria as they are difficult to be eradicated. Toxin-antitoxin (TA) systems are genetic elements located in most prokaryotic genomes.
Nawal S. Gouda, Amira M. Sultan
core   +1 more source

Comparative genomics of vancomycin-resistant Staphylococcus aureus strains and their positions within the clade most commonly associated with methicillin-resistant S. aureus hospital-acquired infection in the United States [PDF]

, 2012
This research was supported in part with federal funds from the NIAID/NIH/DHHS, including the Harvard-wide Program on Antibiotic Resistance (NIH grant AI083214), NIH grant EY017381 (M.S.G.), contract HHSN27220090018C, and the NARSA program supported ...
Griggs, Allison, Van Tonder, Andries, Allison Griggs, Mongodin, Emmanuel F., Kip Bodi, Bruce Birren, Palmer, Kelli L., Brian J. Haas, Bodi, Kip, Paul Godfrey, Haas, Brian J., Kelli L. Palmer, Birren, Bruce, Emmanuel F. Mongodin, Michael S. Gilmore, Cerqueira, Gustavo, Holden, Matthew T. G., Feldgarden, Michael, Gustavo Cerqueira, Wortman, Jennifer, Lawley, Trevor, Kos, Veronica N., Matthew T. G. Holden, Trevor Lawley, Gilmore, Michael, Jennifer Wortman, Michael Feldgarden, Christopher A. Desjardins, Godfrey, Paul, Steven R. Gill, Desjardins, Christopher A., Andries Van Tonder, Veronica N. Kos, Gilmore, Michael S., Gill, Steven R.   +34 more
core   +1 more source

The Nephrotoxicity of Vancomycin [PDF]

Clinical Pharmacology & Therapeutics, 2017
Vancomycin use is often associated with nephrotoxicity. It remains uncertain, however, to what extent vancomycin is directly responsible, as numerous potential risk factors for acute kidney injury frequently coexist. Herein, we critically examine available data in adult patients pertinent to this question.
Filippone, Edward J., Kraft, Walter K., Farber, John L.   +2 more
openaire   +2 more sources

Resveratrol Ameliorates Vancomycin-Induced Testicular Dysfunction in Male Rats

Medicina, 2023
Background and Objectives: Numerous studies have indicated that antibiotics may adversely affect testicular and sperm function. As an alternative to penicillin, vancomycin is a glycopeptide antibiotic developed to treat resistant strains of ...
Fahad S. Alshehri
doaj   +1 more source

Prediction of Unbound Vancomycin Levels in Intensive Care Unit and Nonintensive Care Unit Patients: Total Bilirubin May Play an Important Role

Infection and Drug Resistance, 2021
Xiao Li,1,* Wen Xu,1,* Ran Li,2 Qie Guo,1 Xiangpeng Li,1 Jialin Sun,1 Shuhong Sun,1 Jing Li1 1Department of Clinical Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266003, People’s Republic of China; 2Department of ...
Li X, Xu W, Li R, Guo Q, Li X, Sun J, Sun S, Li J   +7 more
doaj  

Vancomycin-Loaded Porphyrinic MOF Nanoparticles for Killing Pathogenic Bacteria

, 2023
The synthesis of functional antibacterial nanoplatforms for killing pathogenic bacteria is urgent. Among them, combining traditional antibiotics with antimicrobial photodynamic therapy (PDT) is an attractive means.
Han Zou (8762814), Yudong Wang (17331), Min Zhou (173135), Hongxun Wang (9667714), Huajuan Wang (5917487), Yiming Wu (295996)   +5 more
core   +1 more source

Oral vancomycin desensitisation to treat Clostridium difficile infection in a vancomycin allergic patient

World Allergy Organization Journal, 2013
The prevalence of Clostridium difficile infection (CDI) is increasing worldwide. Oral vancomycin is an effective and frequently used treatment. However, patients with CDI who are allergic to intravenous vancomycin cannot receive oral vancomycin due to ...
Shanti Mahabir, Ren Yik Lim, Fidelma Fitzpatrick, Colm Magee, Mary Keogan   +4 more
doaj   +1 more source

Systematic review of efficacy, safety and pharmacokinetics of intravenous and intraventricular vancomycin for central nervous system infections

Frontiers in Pharmacology, 2022
Objective: The decision of vancomycin dosage for central nervous system (CNS) infections is still a challenge because its bactericidal nature in cerebrospinal fluid (CSF) has not been confirmed by human studies.
Shu-Ping Liu, Jing Xiao, Ya-Li Liu, Yue-E Wu, Hui Qi, Zhuang-Zhuang Wang, A-Dong Shen, A-Dong Shen, Gang Liu, Wei Zhao, Wei Zhao   +10 more
doaj   +1 more source

Vancomycin: A History [PDF]

Clinical Infectious Diseases, 2006
Vancomycin became available for clinical use >50 years ago but was soon discarded in favor of other antibiotics that were deemed to be more efficacious and less toxic. The advent of pseudomembranous enterocolitis, coupled with the spread of methicillin-resistant Staphylococcus aureus, led to a resurgence in the use of vancomycin.
openaire   +2 more sources

Clinical Application Value of Pharmacokinetic Parameters of Vancomycin in Children Treated in the Pediatric Intensive Care Unit

Frontiers in Pediatrics, 2022
ObjectiveTo explore the efficacy and safety of vancomycin as measured by pharmacokinetic/pharmacodynamic parameters in children with severe infection in the Pediatric Intensive Care Unit (PICU) and to determine the appropriate threshold for avoiding ...
Bo Zhou, Bo Zhou, Bo Zhou, Bo Zhou, Wenyi Xiong, Ke Bai, Ke Bai, Ke Bai, Ke Bai, Hongxing Dang, Hongxing Dang, Hongxing Dang, Hongxing Dang, Jing Li, Jing Li, Jing Li, Jing Li, Feng Xu, Feng Xu, Feng Xu, Feng Xu, Yue-qiang Fu, Yue-qiang Fu, Yue-qiang Fu, Yue-qiang Fu, Chengjun Liu, Chengjun Liu, Chengjun Liu, Chengjun Liu   +28 more
doaj   +1 more source