Results 1 to 10 of about 107,851 (315)
The Nephrotoxicity of Vancomycin. [PDF]
Clinical Pharmacology & Therapeutics, 2017 Vancomycin use is often associated with nephrotoxicity. It remains uncertain, however, to what extent vancomycin is directly responsible, as numerous potential risk factors for acute kidney injury frequently coexist. Herein, we critically examine available data in adult patients pertinent to this question.
Farber, John L. +2 more
core +5 more sources
Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy [PDF]
The Korean Journal of Internal Medicine, 2021 Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity.
Jin Won Kim +12 more
doaj +1 more source
Sex Difference in Cisplatin-Induced Nephrotoxicity: Laboratory and Clinical Findings
Journal of Toxicology, 2022 Cisplatin (CP) as the most important anticancer drug has limited usage due to a lot of side effects such as nephrotoxicity. Additionally, nephrotoxicity is gender/sex-related.
Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh
doaj +1 more source
Asian Pacific Journal of Cancer Biology, 2022 Introduction: Head and neck cancers are the common cancers in developing countries, especially in Southeast Asia. Concurrent chemoradiation is the treatment of choice for locally advanced stage III to IVB squamous cell carcinoma of head and neck ...
Mahfujul Ahmed Riad
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2023 Billions of people worldwide have experienced irreversible kidney injuries, which is mainly attributed to the complexity of drug-induced nephrotoxicity.
Kexing Xi +5 more
doaj +1 more source
Frontiers in Pharmacology, 2020 AimAntineoplastic effect of cisplatin, the first line treatment in non-small cell lung cancer (NSCLC), is hindered by its nephrotoxicity and myelotoxicity. Both low-dose and high-dose regimens are used in the management of NSCLC. The aim of this study is
Zulfan Zazuli +9 more
doaj +1 more source
AIDS Research and Treatment, 2011 Highly active antiretroviral therapy (HAART) and other medical therapies for HIV-related infections have been associated with toxicities. Antiretroviral therapy can contribute to renal dysfunction directly by inducing acute tubular necrosis, acute interstitial nephritis, crystal nephropathy, and renal tubular disorders or indirectly via drug ...
Robert Kalyesubula, Mark A. Perazella
openaire +3 more sources
Bibliometric and visual analysis of nephrotoxicity research worldwide
Frontiers in Pharmacology, 2022 Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs.
Tianmu He +9 more
doaj +1 more source
Inhibition of gentamicin–induced renal tubular cell necrosis [PDF]
Journal of Nephropathology, 2012 Gentamicin nephrotoxicity limit its usage against gram negative bacteria. Most researches showed that antioxidant agents improved gentamicin nephrotoxicity.
Majid Tavafi
doaj +1 more source
F1000Research, 2017 Nephrotoxic medication exposure is nearly ubiquitous in hospitalized patients and represents one of the most common causes of acute kidney injury (AKI) in the hospitalized setting. Although provision of medications that are nephrotoxic has led to improved outcomes in terms of treatment of underlying illness, unnecessary nephrotoxic medication exposure ...
openaire +2 more sources