Results 31 to 40 of about 72,055 (308)
P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells. [PDF]
PLoS ONE, 2015 The pathogenesis of colistin induced nephrotoxicity is poorly understood. Currently there are no effective therapeutic or prophylactic agents available.
Sun-hyo Lee +5 more
doaj +1 more source
Gelofusine Ameliorates Colistin-Induced Nephrotoxicity [PDF]
, 2017 Colistin therapy is used as the last line of defense against life-threatening Gram-negative infections. Nephrotoxicity is the major dose-limiting side effect that impedes optimal dosing of patients.
Maizbha U. Ahmed +8 more
core +3 more sources
Selenium alleviates porcine nephrotoxicity of ochratoxin A by improving selenoenzyme expression in vitro. [PDF]
PLoS ONE, 2015 Ochratoxin A (OTA), a mycotoxin, is a potent nephrotoxin in humans and animals. Selenium (Se) is an essential micronutrient for humans and animals, and plays a key role in antioxidant defense.
Fang Gan +4 more
doaj +1 more source
Tacrolimus-induced nephrotoxicity and genetic variability:A review [PDF]
, 2012 Background: Calcineurin inhibition (CNI) is the mainstay of immunosuppressant therapy for most solid organ transplant patients. High tacrolimus levels are related with acute nephrotoxicity, but the relationship with chronic toxicity is less clear ...
Koren, Gideon +5 more
core +1 more source
International Journal of Infectious DiseasesObjectives: To compare nephrotoxicity between teicoplanin and vancomycin in older patients, investigate the correlation between teicoplanin average steady-state trough concentrations (Cmin,ss) and nephrotoxicity, and identify independent risk factors for
Jionghe Wu +11 more
doaj +1 more source
Role of probiotics in the management of cisplatin-induced nephrotoxicity
Medicine in MicroecologyNew research shows that gut microbes have a role in the management of cisplatin-induced nephrotoxicity, with underlying processes involving mucosal and/or systemic inflammation or metabolic abnormalities.
Serina Easmin +7 more
doaj +1 more source
Tenofovir Nephrotoxicity: 2011 Update [PDF]
, 2011 Tenofovir is an acyclic nucleotide analogue reverse-transcriptase inhibitor structurally similar to the nephrotoxic drugs adefovir and cidofovir. Tenofovir is widely used to treat HIV infection and approved for treatment of hepatitis B virus.
Parra-Rodríguez, Alejandro +25 more
core +1 more source
Colistin-induced Nephrotoxicity: Experience from a University Hospital
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021 Introduction: Colistin has been widely used in the treatment of infections caused by multidrug-resistant bacteria. This study aimed to determine the frequency and risk factors of colistin-related nephrotoxicity.
Pınar BAKIR EKİNCİ +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Hepatology, EarlyView., 2022 Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino +14 more
wiley +1 more source