Results 31 to 40 of about 78,162 (300)
Antibiotics, 2021 Multidrug-resistant Gram-negative infection is a major global public health threat. Currently, colistin is considered the last-resort treatment despite its nephrotoxicity.
Pornpen Sangthawan +5 more
doaj +1 more source
Determination of colistin-related nephrotoxicity and risk factors in intensive care unit
İstanbul Kuzey Klinikleri, 2018 INTRODUCTION[|]Colistin is a cationic polypeptide antibiotic with a cyclic structure that belongs to the polymyxin group. It was banned from clinical use because of its significant renal side effects, such as nephrotoxicity.
Ayse Inci +4 more
doaj +1 more source
Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells [PDF]
, 2012 End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed the nephrotoxicity induced by the immunosuppressive agents’ cyclosporine A (CsA ...
Ryan, Michael P. +7 more
core +1 more source
International Journal of Bipolar Disorders, 2015 AbstractReports of toxic effects on the kidney of lithium treatment emerged very soon after lithium therapy was introduced. Lithium-induced nephrogenic diabetes insipidus is usually self-limiting or not clinically dangerous. Some reports of irreversible chronic kidney disease and renal failure were difficult to attribute to lithium treatment since ...
Azab, Abed N. +5 more
openaire +2 more sources
Life, 2021 Cyclosporine A (CyA) is an immunosuppressive agent that induces nephrotoxicity with long-term treatment. The roles of DPP-4 and its inhibitors in cyclosporine nephrotoxicity are not fully understood.
Hye Sook Min +7 more
doaj +1 more source
Cisplatin Nephrotoxicity and Longitudinal Growth in Children With Solid Tumors: A Retrospective Cohort Study [PDF]
, 2015 Cisplatin, a major antineoplastic drug used in the treatment of solid tumors, is a known nephrotoxin. This retrospective cohort study evaluated the prevalence and severity of cisplatin nephrotoxicity in 54 children and its impact on height and weight.We ...
Castañeda-Hernández, Gilberto +11 more
core +2 more sources
P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells. [PDF]
PLoS ONE, 2015 The pathogenesis of colistin induced nephrotoxicity is poorly understood. Currently there are no effective therapeutic or prophylactic agents available.
Sun-hyo Lee +5 more
doaj +1 more source
International Journal of Infectious DiseasesObjectives: To compare nephrotoxicity between teicoplanin and vancomycin in older patients, investigate the correlation between teicoplanin average steady-state trough concentrations (Cmin,ss) and nephrotoxicity, and identify independent risk factors for
Jionghe Wu +11 more
doaj +1 more source
Selenium alleviates porcine nephrotoxicity of ochratoxin A by improving selenoenzyme expression in vitro. [PDF]
PLoS ONE, 2015 Ochratoxin A (OTA), a mycotoxin, is a potent nephrotoxin in humans and animals. Selenium (Se) is an essential micronutrient for humans and animals, and plays a key role in antioxidant defense.
Fang Gan +4 more
doaj +1 more source
AIDS Research and Treatment, 2011 Highly active antiretroviral therapy (HAART) and other medical therapies for HIV-related infections have been associated with toxicities. Antiretroviral therapy can contribute to renal dysfunction directly by inducing acute tubular necrosis, acute interstitial nephritis, crystal nephropathy, and renal tubular disorders or indirectly via drug ...
Robert Kalyesubula, Mark A. Perazella
openaire +3 more sources