Results 11 to 20 of about 78,162 (300)
Bisphosphonate nephrotoxicity [PDF]
Kidney International, 2008 Bisphosphonates are valuable agents for the treatment of post-menopausal osteoporosis (PMO), hypercalcemia of malignancy, and osteolytic bone metastases. Oral bisphosphonates are used mainly to treat PMO and are not associated with significant nephrotoxicity.
Perazella, Mark A., Markowitz, Glen S.
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Türk Yoğun Bakim Derneği Dergisi, 2014 Objective: The aim of our study, is to determine the nephrotoxicity rates and risk factors for the development of nephrotoxicity by retrospective evaluation of patients who were given colistin therapy oncology hospital intensive care unit.
Menşure Kaya +6 more
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Experimental Cell Line Models for Nephrotoxicity Screening [PDF]
Регуляторные исследования и экспертиза лекарственных средств, 2021 The aim of the study was to review literature data on cell models for experimental assessment of drug nephrotoxicity in vitro. Because of nephrotoxicity, 2% of new investigational medicinal products are discarded at the stage of preclinical in vivo ...
I. A. Mazerkina +4 more
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Drug Design, Development and Therapy, 2018 Tianyi Xia, Sang Zhu, Yan Wen, Shouhong Gao, Mingming Li, Xia Tao, Feng Zhang, Wansheng Chen Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, People’s Republic of China Background: Nephrotoxicity of ...
Xia T +7 more
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Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy [PDF]
The Korean Journal of Internal Medicine, 2021 Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity.
Jin Won Kim +12 more
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Drug-Induced Nephrotoxicity: A Review [PDF]
المجلة العراقية للصيدلة, 2022 Background: Nephrotoxicity is referred to as rapid degeneration in kidney functioning due to the toxic effects of medications. The glomerulus and proximal renal tubule are the fundamental portions of the nephron to be affected by drugs leading to ...
Muthanna Khalaf, Zeina Althanoon
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Sex Difference in Cisplatin-Induced Nephrotoxicity: Laboratory and Clinical Findings
Journal of Toxicology, 2022 Cisplatin (CP) as the most important anticancer drug has limited usage due to a lot of side effects such as nephrotoxicity. Additionally, nephrotoxicity is gender/sex-related.
Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh
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Asian Pacific Journal of Cancer Biology, 2022 Introduction: Head and neck cancers are the common cancers in developing countries, especially in Southeast Asia. Concurrent chemoradiation is the treatment of choice for locally advanced stage III to IVB squamous cell carcinoma of head and neck ...
Mahfujul Ahmed Riad
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Mechanisms of calcineurin inhibitor nephrotoxicity in chronic allograft injury [PDF]
, 2012 The first successful transplantation of a human kidney was performed more than 50 years ago by Murray and colleagues in 1954 between identical twins. The success of this transplantation was due to the fact that no significant rejection occurs between ...
Ryan, Michael P. +4 more
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Frontiers in Pharmacology, 2020 AimAntineoplastic effect of cisplatin, the first line treatment in non-small cell lung cancer (NSCLC), is hindered by its nephrotoxicity and myelotoxicity. Both low-dose and high-dose regimens are used in the management of NSCLC. The aim of this study is
Zulfan Zazuli +9 more
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