Results 1 to 10 of about 6,272,911 (310)

Optimal Management of the Public and Patients by Pharmacists in the Era of COVID-19: An Evidence-Based Review and Practical Recommendations

Frontiers in Public Health, 2022
Purpose: Currently, managing the public and patients during the COVID-19 pandemic is constituting a health care challenge worldwide. Patient-oriented management is of crucial importance to promote emergency preparedness and response.
Zaiwei Song, Zaiwei Song, Zaiwei Song, Yang Hu, Yang Hu, Yang Hu, Yang Hu, Zhenyu Ren, Zhenyu Ren, Zhenyu Ren, Guanru Wang, Guanru Wang, Guanru Wang, Guanru Wang, Shuang Liu, Shuang Liu, Shuang Liu, Siqian Zheng, Siqian Zheng, Siqian Zheng, Li Yang, Li Yang, Li Yang, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +25 more
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The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2021
Objective: High-dose methotrexate (HDMTX) is a mainstay therapeutic agent for the treatment of diverse hematological malignancies, and it plays a significant role in interindividual variability regarding the pharmacokinetics and toxicity.
Zaiwei Song, Zaiwei Song, Zaiwei Song, Yang Hu, Yang Hu, Yang Hu, Yang Hu, Shuang Liu, Shuang Liu, Shuang Liu, Dan Jiang, Dan Jiang, Dan Jiang, Dan Jiang, Zhanmiao Yi, Zhanmiao Yi, Zhanmiao Yi, Mason M. Benjamin, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +20 more
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Pharmacokinetics of Levodopa and 3-O-Methyldopa in Parkinsonian Patients Treated with Levodopa and Ropinirole and in Patients with Motor Complications

Pharmaceutics, 2021
Parkinson’s disease (PD) is a progressive, neurodegenerative disorder primarily affecting dopaminergic neuronal systems, with impaired motor function as a consequence.
Urszula Adamiak-Giera, Wojciech Jawień, Anna Pierzchlińska, Monika Białecka, Jan Dariusz Kobierski, Tomasz Janus, Barbara Gawrońska-Szklarz   +6 more
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Knowledge, Attitudes and Practice of Healthcare Providers, Healthcare Regulatory Practitioners and Patients Toward Biosimilars in China: Insights From a Nationwide Survey

Frontiers in Pharmacology, 2022
Objective: With increasing numbers of biosimilars entering the market or in the approval pipeline in China, understanding the current awareness and attitudes of biosimilars still remains the first step to promote uptake.
Yang Hu, Yang Hu, Yang Hu, Yang Hu, Zaiwei Song, Zaiwei Song, Zaiwei Song, Dan Jiang, Dan Jiang, Dan Jiang, Dan Jiang, Lin Zhuo, Yinchu Cheng, Yinchu Cheng, Yinchu Cheng, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +17 more
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Total and Unbound Pharmacokinetics of Cefiderocol in Critically Ill Patients

Pharmaceutics, 2022
Background: Cefiderocol is a siderophore cephalosporin antibiotic active against Gram-negative bacteria, including extended-spectrum beta-lactamase and carbapenemase-producing strains.
Noël Zahr, Saik Urien, Benoit Llopis, Gaëlle Noé, Nadine Tissot, Kevin Bihan, Helga Junot, Clémence Marin, Bochra Mansour, Charles-Edouard Luyt, Alexandre Bleibtreu, Christian Funck-Brentano   +11 more
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Vancomycin Therapeutic Drug Monitoring [PDF]

Pediatric Infectious Disease, 2023
Introduction: Vancomycin is effective against gram-positive bacteria including staphylococcus aureus which are resistant to methicillin. Vancomycin has a narrow therapeutic range and is associated with adverse drug reactions related to iv infusion ...
Bhaskar Shenoy, Devesh N Joshi, Pooja Doddikoppad   +2 more
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Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review

Frontiers in Psychiatry, 2023
BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu, Na Xu, Zaiwei Song, Zaiwei Song, Zaiwei Song, Dan Jiang, Dan Jiang, Dan Jiang, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +10 more
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Toward Therapeutic Drug Monitoring of Lenalidomide in Hematological Malignancy? Results of an Observational Study of the Exposure-Safety Relationship

Frontiers in Pharmacology, 2022
Objective: Continuous lenalidomide (LEN) therapy is important to achieve a therapeutic effect in patients with multiple myeloma (MM) and non-Hodgkin lymphoma (NHL).
Zaiwei Song, Zaiwei Song, Lan Ma, Li Bao, Yi Ma, Yi Ma, Ping Yang, Ping Yang, Dan Jiang, Dan Jiang, Aijun Liu, Lu Zhang, Yan Li, Yinchu Cheng, Yinchu Cheng, Fei Dong, Rongsheng Zhao, Rongsheng Zhao, Hongmei Jing   +18 more
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Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan® products through human skin

Frontiers in Pharmacology, 2023
In the treatment of pain, especially chronic pain, the rule of multimodal therapy applies, based on various painkillers mechanisms of action. The aim of the conducted study was to evaluate the in vitro penetration of ketoprofen (KET) and lidocaine ...
Urszula Adamiak-Giera, Anna Nowak, Wiktoria Duchnik, Paula Ossowicz-Rupniewska, Anna Czerkawska, Anna Machoy-Mokrzyńska, Tadeusz Sulikowski, Łukasz Kucharski, Marta Białecka, Adam Klimowicz, Monika Białecka   +10 more
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Systematic review and meta-analysis on the therapeutic reference range for escitalopram: Blood concentrations, clinical effects and serotonin transporter occupancy

Frontiers in Psychiatry, 2022
IntroductionA titration within a certain therapeutic reference range presupposes a relationship between the blood concentration and the therapeutic effect of a drug. However, this has not been systematically investigated for escitalopram.
Luzie Eichentopf, Christoph Hiemke, Christoph Hiemke, Andreas Conca, Andreas Conca, Jan Engelmann, Manfred Gerlach, Manfred Gerlach, Ursula Havemann-Reinecke, Ursula Havemann-Reinecke, Gudrun Hefner, Gudrun Hefner, Vincenzo Florio, Maxim Kuzin, Maxim Kuzin, Klaus Lieb, Margareta Reis, Margareta Reis, Thomas G. Riemer, Alessandro Serretti, Georgios Schoretsanitis, Georgios Schoretsanitis, Georgios Schoretsanitis, Georgios Schoretsanitis, Gerald Zernig, Gerald Zernig, Gerald Zernig, Gerhard Gründer, Gerhard Gründer, Xenia M. Hart, Xenia M. Hart   +30 more
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