Results 1 to 10 of about 417,988 (310)

Therapeutic Drug Monitoring of Antiarrhythmic Drugs

Clinical Pharmacokinetics, 2003
Most antiarrhythmic drugs fulfil the formal requirements for rational use of therapeutic drug monitoring, as they show highly variable plasma concentration profiles at a given dose and a direct concentration-effect relationship. Therapeutic ranges for antiarrhythmic drugs are, however, often very poorly defined.
Gesche, Jürgens, Niels A, Graudal, Jens P, Kampmann   +2 more
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Therapeutic drug monitoring of cyclosporine

Transplantation Proceedings, 2004
Therapeutic drug monitoring of cyclosporine has been established as part of the routine clinical treatment for patients after organ transplantation. The inability to define optimal dose (maximize efficacy/minimize toxicity) has been a problem related to drug monitoring of cyclosporine.
A, Jorga, D W, Holt, A, Johnston
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TDM: Therapeutic Drug Measuring or Therapeutic Drug Monitoring?

Therapeutic Drug Monitoring, 2005
The third round of the International Interlaboratory Quality Control Program for Therapeutic Drug Monitoring in HIV infection (QC-program) consisted of the analysis not only of plasma samples but also of patient cases. The case was composed of different topics related to the therapeutic drug monitoring of antiretroviral drugs.
Droste, J.A.H., Koopmans †, P.P., Hekster, Y.A., Burger, D.M.   +3 more
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Immunoassays in Therapeutic Drug Monitoring

Clinics in Laboratory Medicine, 1987
Numerous immunoassay methods are now in routine use for therapeutic drug monitoring of drugs and metabolites. Most methods are homogeneous immunoassays with excellent specificity, accuracy, and precision. In addition, these assays are readily automated, and commercial versions of theses reagents are available with dedicated instrumentation. This report
L J, Blecka, G J, Jackson
openaire   +2 more sources

Therapeutic Drug Monitoring of the Antimycobacterial Drugs

Clinics in Laboratory Medicine, 1996
Because MDR tuberculosis and MAC are difficult to treat, TDM with the antimycobacterial drugs has become the standard of practice at NJC. By combining specific and sensitive assays, carefully collected samples, and clinical expertise, we are able to control and optimize antimycobacterial drug therapy.
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[Therapeutic drug monitoring of antimicrobials].

Nederlands tijdschrift voor geneeskunde, 2014
Contains fulltext : 136169.pdf (Publisher’s version ) (Closed access)
Mouton, J.W., Aarnoutse, R.E.
openaire   +3 more sources

Glucuronidation in therapeutic drug monitoring

Clinica Chimica Acta, 2005
Glucuronidation is a major drug-metabolizing reaction in humans. A pharmacological effect of glucuronide metabolites is frequently neglected and the value of therapeutic drug monitoring has been questioned. However, this may not always be true.In this review the impact of glucuronidation on therapeutic drug monitoring has been evaluated on the basis of
Maria, Shipkova, Eberhard, Wieland
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Office Therapeutic Drug Monitoring

Primary Care: Clinics in Office Practice, 1986
Considerations necessary for appropriate therapeutic drug monitoring in the office practice setting have been presented. Practical issues focusing on clinical pharmacokinetics as well as serum drug concentration evaluation methods and techniques have been reviewed, with emphasis on orally administered medications.
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Therapeutic Drug Monitoring of Lamotrigine

Annals of Pharmacotherapy, 2002
OBJECTIVE: To evaluate the usefulness of routine monitoring of serum lamotrigine concentration. DATA SOURCE: Literature was accessed through MEDLINE (1990–January 2001).
Elaine, Chong, L Lee, Dupuis
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Therapeutic Drug Monitoring in Saliva

Clinical Pharmacokinetics, 1978
The observation that drug concentrations in saliva are often proportional to the concentrations in plasma has led to the suggestion that in therapeutic drug monitoring, or in pharmacokinetic studies in general, saliva might be substituted for plasma.
M, Danhof, D D, Breimer
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