Results 11 to 20 of about 390,704 (258)

Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan® products through human skin

open access: yesFrontiers in Pharmacology, 2023
In the treatment of pain, especially chronic pain, the rule of multimodal therapy applies, based on various painkillers mechanisms of action. The aim of the conducted study was to evaluate the in vitro penetration of ketoprofen (KET) and lidocaine ...
Urszula Adamiak-Giera   +10 more
doaj   +1 more source

Systematic review and meta-analysis on the therapeutic reference range for escitalopram: Blood concentrations, clinical effects and serotonin transporter occupancy

open access: yesFrontiers in Psychiatry, 2022
IntroductionA titration within a certain therapeutic reference range presupposes a relationship between the blood concentration and the therapeutic effect of a drug. However, this has not been systematically investigated for escitalopram.
Luzie Eichentopf   +30 more
doaj   +1 more source

Mapping Evidence of Pharmacy Services for COVID-19 in China

open access: yesFrontiers in Pharmacology, 2020
ObjectiveTo explore the role of pharmacists and innovation of pharmacy interventions for COVID-19 patients in China.MethodsWe comprehensively searched PubMed and Chinese databases Sinomed, China National Knowledge Infrastructure to identify articles ...
Zhan-Miao Yi   +13 more
doaj   +1 more source

Therapeutic drug monitoring: antiarrhythmic drugs [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1998
Antiarrhythmic agents are traditionally classified according to Vaughan Williams into four classes of action. Class I antiarrhythmic agents include most of the drugs traditionally thought of as antiarrhythmics, and have as a common action, blockade of the fast‐inward sodium channel on myocardium. These agents have a very significant toxicity, and while
T J, Campbell, K M, Williams
openaire   +4 more sources

Arterial Blood Pressure Variability and Other Vascular Factors Contribution to the Cognitive Decline in Parkinson’s Disease

open access: yesMolecules, 2021
Dementia is one of the most disabling non-motor symptoms in Parkinson’s disease (PD). Unlike in Alzheimer’s disease, the vascular pathology in PD is less documented.
Anna Pierzchlińska   +4 more
doaj   +1 more source

The impact of clinical pharmacists’ intervention on the rational use of intravenous paracetamol vials in Baghdad Teaching Hospital: A case-control study [PDF]

open access: yesPharmacia
Paracetamol has been recognized worldwide as a safe and effective agent for relieving pain and reducing fever in many patients. This study aimed to investigate the role of clinical pharmacist interventions in the rational and appropriate use of ...
Kawthar Faris Nassir   +7 more
doaj   +3 more sources

Rosemary and CoQ10 Alleviated the Detrimental Effects of Concomitant Administration of Acetaminophen and Carbamazepine by Accelerating Their Metabolism and Elimination

open access: yesIndonesian Biomedical Journal, 2022
BACKGROUND: The interaction of carbamazepine (CBZ) and acetaminophen (APAP) could result in hepatic failure and mortality. This study was conducted to analyzed the potential of rosemary ethanol extract (REE) or coenzyme Q10 (CoQ10) to alleviate the ...
Marwa Magdy Hamido   +3 more
doaj   +1 more source

Voriconazole Therapeutic Drug Monitoring [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2006
ABSTRACT We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship ( P < 0.025) between disease progression and drug concentration was detected. Favorable responses were observed in 10/10 patients with concentrations above 2.05 μg/ml, while
J, Smith   +6 more
openaire   +2 more sources

TGF-β1 and TGFβR2 Gene Polymorphisms in Patients with Unstable Angina

open access: yesBiomedicines, 2023
Acute coronary syndromes result from a sudden reduction in the lumen of a coronary artery as a result of atherosclerotic plaque rupture, its swelling or the formation of thrombotic lesions.
Damian Malinowski   +2 more
doaj   +1 more source

Comparation of time-course, dose-effect, influencing factors and adverse events of biologics in the treatment of adults with moderate to severe plaque psoriasis

open access: yesFrontiers in Immunology, 2023
IntroductionBiologics is used for treating moderate to severe plaque psoriasis (MSPP), which represent one of the foremost therapeutic advancements in disease of dermatology.
Weiqi Gao   +10 more
doaj   +1 more source

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