Results 11 to 20 of about 417,988 (310)
Therapeutic Drug Monitoring of Antiepileptic Drugs
Commonly used conventional antiepileptic drugs for pharmacotherapy in epilepsy are phenytoin, carbamazepine and valproic acid. These drugs have complex pharmacokinetic properties leading to fluctuation in their plasma level at given same therapeutic dose.
Geeta Shakya +3 more
doaj +4 more sources
Therapeutic drug monitoring of imatinib [PDF]
In this issue of the Revista Brasileira de Hematologia e Hemoterapia, Martins et al.(1) are publishing an interesting review, a meta-analysis, of the clinical and analytical aspects of therapeutic drug monitoring of imatinib in chronic myeloid leukemia (CML). Imatinib, the archetype for tyrosine kinase inhibitor therapeutics, is an excellent example
Pierre Wallemacq
doaj +6 more sources
Purpose: Currently, managing the public and patients during the COVID-19 pandemic is constituting a health care challenge worldwide. Patient-oriented management is of crucial importance to promote emergency preparedness and response.
Zaiwei Song +25 more
doaj +1 more source
Objective: High-dose methotrexate (HDMTX) is a mainstay therapeutic agent for the treatment of diverse hematological malignancies, and it plays a significant role in interindividual variability regarding the pharmacokinetics and toxicity.
Zaiwei Song +20 more
doaj +1 more source
Vancomycin Therapeutic Drug Monitoring [PDF]
Introduction: Vancomycin is effective against gram-positive bacteria including staphylococcus aureus which are resistant to methicillin. Vancomycin has a narrow therapeutic range and is associated with adverse drug reactions related to iv infusion ...
Bhaskar Shenoy +2 more
doaj +1 more source
Therapeutic drug monitoring [PDF]
Traditionally, therapeutic drug monitoring has been used for the management of epilepsy, cardiac arrhythmias, asthma and depression. This review provides an update, particularly for the newer clinical applications, and how therapeutic drug monitoring (including use of analytical and interpretation tools) can improve clinical outcomes.Improved drug ...
Gillian M, Shenfield, Raymond G, Morris
openaire +4 more sources
Parkinson’s disease (PD) is a progressive, neurodegenerative disorder primarily affecting dopaminergic neuronal systems, with impaired motor function as a consequence.
Urszula Adamiak-Giera +6 more
doaj +1 more source
Total and Unbound Pharmacokinetics of Cefiderocol in Critically Ill Patients
Background: Cefiderocol is a siderophore cephalosporin antibiotic active against Gram-negative bacteria, including extended-spectrum beta-lactamase and carbapenemase-producing strains.
Noël Zahr +11 more
doaj +1 more source
On-Site Therapeutic Drug Monitoring [PDF]
Recent technological advances have stimulated efforts to bring personalized medicine into practice. Yet, traditional application fields like therapeutic drug monitoring (TDM) have remained rather under-appreciated. Owing to clear dose-response relationships, TDM could improve patient outcomes and reduce healthcare costs.
Ates, H. Ceren +5 more
openaire +5 more sources
Objective: With increasing numbers of biosimilars entering the market or in the approval pipeline in China, understanding the current awareness and attitudes of biosimilars still remains the first step to promote uptake.
Yang Hu +17 more
doaj +1 more source

