Results 11 to 20 of about 5,801,365 (309)

On-Site Therapeutic Drug Monitoring [PDF]

Trends in Biotechnology, 2020
Recent technological advances have stimulated efforts to bring personalized medicine into practice. Yet, traditional application fields like therapeutic drug monitoring (TDM) have remained rather under-appreciated. Owing to clear dose-response relationships, TDM could improve patient outcomes and reduce healthcare costs.
Ates, H. Ceren, Roberts, Jason A., Lipman, Jeffrey, Cass, Anthony E.G., Urban, Gerald A., Dincer, Can   +5 more
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Toward Therapeutic Drug Monitoring of Lenalidomide in Hematological Malignancy? Results of an Observational Study of the Exposure-Safety Relationship

Frontiers in Pharmacology, 2022
Objective: Continuous lenalidomide (LEN) therapy is important to achieve a therapeutic effect in patients with multiple myeloma (MM) and non-Hodgkin lymphoma (NHL).
Zaiwei Song, Zaiwei Song, Lan Ma, Li Bao, Yi Ma, Yi Ma, Ping Yang, Ping Yang, Dan Jiang, Dan Jiang, Aijun Liu, Lu Zhang, Yan Li, Yinchu Cheng, Yinchu Cheng, Fei Dong, Rongsheng Zhao, Rongsheng Zhao, Hongmei Jing   +18 more
doaj   +1 more source

Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan® products through human skin

Frontiers in Pharmacology, 2023
In the treatment of pain, especially chronic pain, the rule of multimodal therapy applies, based on various painkillers mechanisms of action. The aim of the conducted study was to evaluate the in vitro penetration of ketoprofen (KET) and lidocaine ...
Urszula Adamiak-Giera, Anna Nowak, Wiktoria Duchnik, Paula Ossowicz-Rupniewska, Anna Czerkawska, Anna Machoy-Mokrzyńska, Tadeusz Sulikowski, Łukasz Kucharski, Marta Białecka, Adam Klimowicz, Monika Białecka   +10 more
doaj   +1 more source

Systematic review and meta-analysis on the therapeutic reference range for escitalopram: Blood concentrations, clinical effects and serotonin transporter occupancy

Frontiers in Psychiatry, 2022
IntroductionA titration within a certain therapeutic reference range presupposes a relationship between the blood concentration and the therapeutic effect of a drug. However, this has not been systematically investigated for escitalopram.
Luzie Eichentopf, Christoph Hiemke, Christoph Hiemke, Andreas Conca, Andreas Conca, Jan Engelmann, Manfred Gerlach, Manfred Gerlach, Ursula Havemann-Reinecke, Ursula Havemann-Reinecke, Gudrun Hefner, Gudrun Hefner, Vincenzo Florio, Maxim Kuzin, Maxim Kuzin, Klaus Lieb, Margareta Reis, Margareta Reis, Thomas G. Riemer, Alessandro Serretti, Georgios Schoretsanitis, Georgios Schoretsanitis, Georgios Schoretsanitis, Georgios Schoretsanitis, Gerald Zernig, Gerald Zernig, Gerald Zernig, Gerhard Gründer, Gerhard Gründer, Xenia M. Hart, Xenia M. Hart   +30 more
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Mapping Evidence of Pharmacy Services for COVID-19 in China

Frontiers in Pharmacology, 2020
ObjectiveTo explore the role of pharmacists and innovation of pharmacy interventions for COVID-19 patients in China.MethodsWe comprehensively searched PubMed and Chinese databases Sinomed, China National Knowledge Infrastructure to identify articles ...
Zhan-Miao Yi, Zhan-Miao Yi, Zhan-Miao Yi, Yang Hu, Yang Hu, Yang Hu, Yang Hu, Guan-Ru Wang, Guan-Ru Wang, Guan-Ru Wang, Guan-Ru Wang, Rong-Sheng Zhao, Rong-Sheng Zhao, Rong-Sheng Zhao   +13 more
doaj   +1 more source

Development of a Therapeutic Drug Monitoring Strategy for the Optimization of Vincristine Treatment in Pediatric Oncology Populations in Africa

, 2023
Background:Recent studies have reported ethnic differences in vincristine exposure and outcomes such as toxicity. This resulted in the hypothesis of subtherapeutic dosing in African children.
Kaspers, Gertjan J. L., Dorlo, Thomas P. C.,, Van der Heijden, Lisa T.,, Alwin D.R. Huitema, Nijstad, A. Laura, Uittenboogaard, Aniek, Beijnen, Jos H., Aniek Uittenboogaard, Beijnen, Jos H.,, Huitema, Alwin D. R., Huitema, Alwin D. R.,, van der Heijden, Lisa T., Uittenboogaard, Aniek,, Gertjan J.L. Kaspers, Dorlo, Thomas P. C., Lisa T. Van der Heijden, Kaspers, Gertjan J. L.,, Thomas P.C. Dorlo, Jos H. Beijnen, A. Laura Nijstad, Nijstad, A. Laura,   +20 more
core   +1 more source

Therapeutic Drug Monitoring of Linezolid in Drug-Resistant Tuberculosis Patients: Clinical Factors and Hematological Toxicities [PDF]

Infection and Drug Resistance
Junjie Cheng,1,* Yuan Yuan,1,* Jinmeng Li,1 Ruoying Zhang,1 Xudong Fan,1 Zhirou Xu,2 Huirong Lin,3 Xinjun Cai,1 Mingfeng Zheng4 1Department of Pharmacy, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, People’s ...
Cheng J, Yuan Y, Li J, Zhang R, Fan X, Xu Z, Lin H, Cai X, Zheng M   +8 more
doaj   +1 more source

The impact of clinical pharmacists’ intervention on the rational use of intravenous paracetamol vials in Baghdad Teaching Hospital: A case-control study [PDF]

Pharmacia
Paracetamol has been recognized worldwide as a safe and effective agent for relieving pain and reducing fever in many patients. This study aimed to investigate the role of clinical pharmacist interventions in the rational and appropriate use of ...
Kawthar Faris Nassir, Adel Hashim, Hayder A. Fawzi, Ali Saad, Osama Zuhair Salman, Zahraa R. Jabbar, Ameer A. Oudah, Aaya Ayad Okab   +7 more
doaj   +3 more sources

Arterial Blood Pressure Variability and Other Vascular Factors Contribution to the Cognitive Decline in Parkinson’s Disease

Molecules, 2021
Dementia is one of the most disabling non-motor symptoms in Parkinson’s disease (PD). Unlike in Alzheimer’s disease, the vascular pathology in PD is less documented.
Anna Pierzchlińska, Magdalena Kwaśniak-Butowska, Jarosław Sławek, Marek Droździk, Monika Białecka   +4 more
doaj   +1 more source

Therapeutic drug monitoring – antiepileptic drugs [PDF]

British Journal of Clinical Pharmacology, 1998
Aims  To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods  The review is based on literature data and observations from clinical practice.
openaire   +10 more sources