Results 31 to 40 of about 6,272,911 (310)

Therapeutic Drug Monitoring of Voriconazole [PDF]

open access: yesTherapeutic Drug Monitoring, 2008
Voriconazole is a triazole antifungal developed for the treatment of life-threatening fungal infections in immunocompromised patients. The drug, which is available for both oral and intravenous administration, has broad-spectrum activity against pathogenic yeasts, dimorphic fungi, and opportunistic molds.
Bruggemann, R.J.M.   +7 more
openaire   +3 more sources

Therapeutic drug monitoring in Turkey: Experiences from Istanbul

open access: yes, 2000
Therapeutic drug monitoring (TDM) has assumed an important place in patient management in the last few decades. In this study, serum drug levels determined in 7759 specimens sent to the Department of Pharmacology and Clinical Pharmacology in 1994 and ...
OZEK, Mehmet   +3 more
core   +1 more source

Therapeutic Drug Monitoring of Antibiotics Is Needed in the Treatment of Sepsis

open access: yesВестник анестезиологии и реаниматологии, 2022
The article presents the results of a prospective one-center observational clinical study.The level of therapeutic drug monitoring antibiotics was studied in patients with sepsis.The objective: to assess the impact of pharmacokinetics and ...
G. P. Plotnikov   +7 more
doaj   +1 more source

Therapeutic drug monitoring of sertraline : Variability factors as displayed in a clinical setting

open access: yes, 2000
This report describes sertraline pharmacokinetics derived from routine therapeutic drug monitoring (TDM) data. A high-performance liquid chromatographic method with ultraviolet detection was established for routine sertraline TDM, and 924 analyses were ...
Reis, Margareta,   +2 more
core   +1 more source

Therapeutic drug monitoring of escitalopram in an outpatient setting

open access: yes, 2007
The main objectives of this study were to outline the inter-and intraindividual and overall pharmacokinetic variability of S-citalopram, S-desmethylcitalopram, and S-didesmethylcitalopram in serum by means of therapeutic drug monitoring; and to ...
Bengtsson, Finn   +7 more
core   +2 more sources

Volumetric Absorptive Microsampling for the Therapeutic Drug Monitoring of Everolimus in Patients Who Have Undergone Liver Transplant

open access: yes, 2023
Background: Therapeutic drug monitoring (TDM) of everolimus is required to prevent organ rejection in patients who have undergone transplant. Volumetric absorptive microsampling (VAMS) is a minimally invasive method for accurately collecting a small ...
주동진
core   +1 more source

Pharmacometrics modeling and simulation to assist phenobarbital dose optimization in dogs

open access: yesFrontiers in Veterinary Science
IntroductionPhenobarbital (PB) remains the first-line treatment for canine epilepsy due to its efficacy, affordability, and favorable pharmacokinetics.
Silvana Alvariza   +6 more
doaj   +1 more source

Exploring the current practices of parenteral nutrition from pharmacists’ perspectives: a qualitative study [PDF]

open access: yesPharmacia
Parenteral nutrition (PN) therapy is indicated to meet patients’ nutritional needs when normal feeding is not feasible. This study was designed to explore current practices and barriers to PN from the perspective of pharmacists.
Omaima Ibrahim Saleh   +2 more
doaj   +3 more sources

Therapeutic Drug Monitoring of Antibody Drugs

open access: yesBiological and Pharmaceutical Bulletin, 2022
In recent years, many antibody drugs that play an important role in the pharmacotherapy of several diseases have been developed. Antibody drugs exhibit immunogenicity in vivo leading to the development of antibodies against the antibody drug (anti-drug antibody). Nonetheless, other factors also affect the pharmacokinetics of antibody drugs.
openaire   +2 more sources

Therapeutic Drug Monitoring for Drugs Used in the Treatment of Substance-Related Disorders: Literature Review Using a Therapeutic Drug Monitoring Appropriateness Rating Scale

open access: yes, 2011
Background: The efficacy of drugs for the treatment of substance-related disorders is moderate at best. Therapeutic drug monitoring (TDM) could be an instrument to improve outcomes.
Brünen, S.   +14 more
core   +1 more source

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