Results 51 to 60 of about 6,272,911 (310)

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Posaconazole Therapeutic Drug Monitoring in a Regional Hospital Setting

, 2016
Background: Posaconazole therapeutic drug monitoring (TDM) is recommended to promote effective antifungal prophylaxis, but its utility has yet to be optimized. Breakthrough invasive fungal infections have been reported with serum concentrations
Patrick J. Lindsay, Norris, Ross, Stuart E. Bond, Spiros Miyakis, Deborah J. E. Marriott, Marriott, Deborah JE, Bond, Stuart E., Miyakis, Spiros, Lindsay, Patrick J, Ross Norris   +9 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

The importance of TNF-α signaling: a potential risk factor in neurodegenerative and cardiovascular diseases

Archives of Medical Science
Cytokines are small, membrane-bound, protein-based cell signaling molecules that aid cell-to-cell communication in physiological and pathological processes. TNF-α is a pleiotropic cytokine that is regarded as a principal cytokine in the acute and chronic
Marta Białecka, Monika Białecka, Anna Machoy-Mokrzyńska, Damian Malinowski, Monika Rać   +4 more
doaj   +1 more source

Therapeutic Drug Monitoring in Inflammatory Bowel Disease

Journal of Coloproctology, 2023
Inflammatory bowel disease (IBD) is a problem that directly affects the quality of life of patients suffering from this condition. Monitoring the serum level of infliximab (IFX) (TDM) is an important tool for guiding therapeutic decisions in IBD patients.
Manoel Alvaro de Freitas Lins Neto, João Otávio Moraes Rolim, Diogo César Maurício de Oliveira Jatobá, Júnia Elisa Carvalho de Meira, Luís Henrique Salvador Filho, Lucas Correia Lins, Jorge Artur Coelho Peçanha   +6 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Therapeutic Drug Monitoring of Ziprasidone in a Clinical Treatment Setting

, 2008
There is limited information on the pharmacokinetics of ziprasidone (ZIP) in naturalistic clinical settings. The objective of this study was to investigate the concentrations of ZIP and its active metabolite S-methyl-dihydroziprasidone (SMDZ), and the ...
Reis, Margareta,, Bengtsson, Finn,, Dolores Cherma Yeste, Maria,, Ahlner, Johan,, Hägg, Staffan,   +4 more
core   +1 more source

Monographs on drugs which are frequently analyzed in therapeutic drug monitoring [PDF]

, 2009
In addition to the monographs which have been published recently by the working group "Drug Monitoring” of the Swiss Society of Clinical Chemistry (SSCC) [1-3], new monographs have been written.
Grignaschi, M, Fathi, M., Werner, Dominique, Rentsch, K., Eap, Chin Bin, Todesco, L, Grignaschi, Nathalie, Werner, D, Thormann, W., Eap, CB, Fathi, Marc, Thormann, W, Todesco, L., Todesco, Liliane, Rentsch, K, Thormann, Wolfgang, Werner, D., Eap, C.B., Magnin, JL, Rentsch, Katharina, Working group “Drug Monitoring”, Magnin, J.L., Fathi, M, Magnin, Jean-Luc, Grignaschi, N.   +24 more
core   +2 more sources

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Therapeutic drug monitoring data on olanzapine and its N-demethyl metabolite in the naturalistic clinical setting

, 2002
Olanzapine (Zyprexa«) was approved for general prescription in Sweden in November 1996, and an HPLC-based therapeutic drug monitoring (TDM) routine for serum olanzapine (OLA) and its major metabolite, N-demethylolanzapine (DMO) was established in ...
Reis, Margareta,, Skogh, Elisabeth,, Dahl, Marja-Liisa, Bengtsson, Finn,, Lundmark, Jöns,, Lundmark, J, Bengtsson, F, Skogh, E, Reis, M, Dahl, ML   +9 more
core   +1 more source