Results 21 to 30 of about 5,801,365 (309)

Therapeutic drug monitoring in drug overdose [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1999
The treatment of poisoned patients is still largely defined by history, clinical assessment and interpretation of ancillary investigations. Measurement of drug concentrations is clinically important for relatively few compounds. Most measurements form an adjunct to and should not be considered a substitute for clinical assessment.
A H, Dawson, I M, Whyte
openaire   +5 more sources

Therapeutic drug monitoring of immunosuppressant drugs [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1999
Individualizing a patient’s drug therapy to obtain the optimum balance between therapeutic efficacy and the occurrence of adverse events is the physician’s goal. However, achieving this goal is not always straight forward, being complicated by within and between patient variability in both pharmacokinetics and pharmacodynamics.
A, Johnston, D W, Holt
openaire   +2 more sources

Rosemary and CoQ10 Alleviated the Detrimental Effects of Concomitant Administration of Acetaminophen and Carbamazepine by Accelerating Their Metabolism and Elimination

open access: yesIndonesian Biomedical Journal, 2022
BACKGROUND: The interaction of carbamazepine (CBZ) and acetaminophen (APAP) could result in hepatic failure and mortality. This study was conducted to analyzed the potential of rosemary ethanol extract (REE) or coenzyme Q10 (CoQ10) to alleviate the ...
Marwa Magdy Hamido   +3 more
doaj   +1 more source

TGF-β1 and TGFβR2 Gene Polymorphisms in Patients with Unstable Angina

open access: yesBiomedicines, 2023
Acute coronary syndromes result from a sudden reduction in the lumen of a coronary artery as a result of atherosclerotic plaque rupture, its swelling or the formation of thrombotic lesions.
Damian Malinowski   +2 more
doaj   +1 more source

Comparation of time-course, dose-effect, influencing factors and adverse events of biologics in the treatment of adults with moderate to severe plaque psoriasis

open access: yesFrontiers in Immunology, 2023
IntroductionBiologics is used for treating moderate to severe plaque psoriasis (MSPP), which represent one of the foremost therapeutic advancements in disease of dermatology.
Weiqi Gao   +10 more
doaj   +1 more source

A Compilation of Serum Concentrations of 12 Antipsychotic Drugs in a Therapeutic Drug Monitoring Setting [PDF]

open access: yes, 2019
BACKGROUND: No comprehensive collection of routine therapeutic drug monitoring data for antipsychotic drugs has been published. METHODS: In this compilation, data on 12 antipsychotics are presented.
Anna K. Jönsson   +8 more
core   +1 more source

Therapeutic Drug Monitoring

open access: yesYAKUGAKU ZASSHI, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tadaaki, Ito   +5 more
openaire   +3 more sources

Therapeutic drug monitoring: antiarrhythmic drugs [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1998
Antiarrhythmic agents are traditionally classified according to Vaughan Williams into four classes of action. Class I antiarrhythmic agents include most of the drugs traditionally thought of as antiarrhythmics, and have as a common action, blockade of the fast‐inward sodium channel on myocardium. These agents have a very significant toxicity, and while
T J, Campbell, K M, Williams
openaire   +4 more sources

Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil

open access: yesClinical Infection in Practice, 2023
Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger   +2 more
doaj   +1 more source

Monitoring of sedation depth in intensive care unit by therapeutic drug monitoring? A prospective observation study of medical intensive care patients

open access: yesJournal of Intensive Care, 2018
Background Analgosedation is a cornerstone therapy for mechanically ventilated patients in intensive care units (ICU). To avoid inadequate sedation and its complications, monitoring of analgosedation is of great importance.
Richard J. Nies   +9 more
doaj   +1 more source

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