Results 21 to 30 of about 390,704 (258)

Therapeutic Drug Monitoring

YAKUGAKU ZASSHI, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tadaaki, Ito, Yumiko, Uchida, Hiromi, Tamura, Shinobu, Hasebe, Masahiro, Igarashi, Masahiro, Hayashi   +5 more
openaire   +3 more sources

Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil

Clinical Infection in Practice, 2023
Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger, J.E. Nagtegaal, M.M. Malingré   +2 more
doaj   +1 more source

Voriconazole Therapeutic Drug Monitoring [PDF]

Journal of the Pediatric Infectious Diseases Society, 2014
A 2-year-old boy being treated for acute lymphoblastic leukemia developed confusion and was found to have a mass on cranial imaging. A neurosurgical biopsy revealed an aspergilloma. Intravenous (iv) voriconazole is administered at 8 mg/kg per dose twice daily.
Zachary, Hoy, Elizabeth S, Dodds Ashley, Geoffrey A, Weinberg, Damian J, Krysan   +3 more
openaire   +2 more sources

Therapeutic drug monitoring – antiepileptic drugs [PDF]

British Journal of Clinical Pharmacology, 1998
Aims  To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods  The review is based on literature data and observations from clinical practice.
openaire   +7 more sources

Therapeutic drug monitoring of immunosuppressant drugs [PDF]

British Journal of Clinical Pharmacology, 1999
Individualizing a patient’s drug therapy to obtain the optimum balance between therapeutic efficacy and the occurrence of adverse events is the physician’s goal. However, achieving this goal is not always straight forward, being complicated by within and between patient variability in both pharmacokinetics and pharmacodynamics.
A, Johnston, D W, Holt
openaire   +2 more sources

Monitoring of sedation depth in intensive care unit by therapeutic drug monitoring? A prospective observation study of medical intensive care patients

Journal of Intensive Care, 2018
Background Analgosedation is a cornerstone therapy for mechanically ventilated patients in intensive care units (ICU). To avoid inadequate sedation and its complications, monitoring of analgosedation is of great importance.
Richard J. Nies, Carsten Müller, Roman Pfister, Philipp S. Binder, Nicole Nosseir, Felix S. Nettersheim, Kathrin Kuhr, Martin H. J. Wiesen, Matthias Kochanek, Guido Michels   +9 more
doaj   +1 more source

Therapeutic drug monitoring in drug overdose [PDF]

British Journal of Clinical Pharmacology, 1999
The treatment of poisoned patients is still largely defined by history, clinical assessment and interpretation of ancillary investigations. Measurement of drug concentrations is clinically important for relatively few compounds. Most measurements form an adjunct to and should not be considered a substitute for clinical assessment.
A H, Dawson, I M, Whyte
openaire   +5 more sources

Therapeutic Drug Monitoring of Antibiotics Is Needed in the Treatment of Sepsis

Вестник анестезиологии и реаниматологии, 2022
The article presents the results of a prospective one-center observational clinical study.The level of therapeutic drug monitoring antibiotics was studied in patients with sepsis.The objective: to assess the impact of pharmacokinetics and ...
G. P. Plotnikov, A. N. Kudryavtsev, A. A. Kleuzovich, A. G. Chizhov, A. A. Ponomarev, S. S. Larin, E. A. Litvin, L. A. Anastasevich   +7 more
doaj   +1 more source

Monitoring of gentamicin blood level in one-week-of-life neonates admitted to a special care nursery ward

Gülhane Tıp Dergisi, 2022
Aims:Gentamicin is routinely used in neonates as an empirical antibiotic for suspected sepsis at a dose of 4.0 mg/kg, either 24 or 36 hourly based on premenstrual age. Regularly, therapeutic drug monitoring is performed.
Suzana Mustafa, Siti Latifah Azirah Mohd Noor, Rozitah Razman, Wan Nazirah Wan Yusuf   +3 more
doaj   +1 more source

Pharmacometrics modeling and simulation to assist phenobarbital dose optimization in dogs

Frontiers in Veterinary Science
IntroductionPhenobarbital (PB) remains the first-line treatment for canine epilepsy due to its efficacy, affordability, and favorable pharmacokinetics.
Silvana Alvariza, Manuel Ibarra, Natalia Guevara, Cecilia Maldonado, Marta Vázquez, Gimena Feijoó, Gonzalo Suárez   +6 more
doaj   +1 more source