Results 21 to 30 of about 417,988 (310)

Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review

Frontiers in Psychiatry, 2023
BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu, Na Xu, Zaiwei Song, Zaiwei Song, Zaiwei Song, Dan Jiang, Dan Jiang, Dan Jiang, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +10 more
doaj   +1 more source

Toward Therapeutic Drug Monitoring of Lenalidomide in Hematological Malignancy? Results of an Observational Study of the Exposure-Safety Relationship

Frontiers in Pharmacology, 2022
Objective: Continuous lenalidomide (LEN) therapy is important to achieve a therapeutic effect in patients with multiple myeloma (MM) and non-Hodgkin lymphoma (NHL).
Zaiwei Song, Zaiwei Song, Lan Ma, Li Bao, Yi Ma, Yi Ma, Ping Yang, Ping Yang, Dan Jiang, Dan Jiang, Aijun Liu, Lu Zhang, Yan Li, Yinchu Cheng, Yinchu Cheng, Fei Dong, Rongsheng Zhao, Rongsheng Zhao, Hongmei Jing   +18 more
doaj   +1 more source

Therapeutic Drug Monitoring of Linezolid in Drug-Resistant Tuberculosis Patients: Clinical Factors and Hematological Toxicities

Infection and Drug Resistance
Junjie Cheng,1,* Yuan Yuan,1,* Jinmeng Li,1 Ruoying Zhang,1 Xudong Fan,1 Zhirou Xu,2 Huirong Lin,3 Xinjun Cai,1 Mingfeng Zheng4 1Department of Pharmacy, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, People’s ...
Cheng J, Yuan Y, Li J, Zhang R, Fan X, Xu Z, Lin H, Cai X, Zheng M   +8 more
doaj   +2 more sources

Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan® products through human skin

Frontiers in Pharmacology, 2023
In the treatment of pain, especially chronic pain, the rule of multimodal therapy applies, based on various painkillers mechanisms of action. The aim of the conducted study was to evaluate the in vitro penetration of ketoprofen (KET) and lidocaine ...
Urszula Adamiak-Giera, Anna Nowak, Wiktoria Duchnik, Paula Ossowicz-Rupniewska, Anna Czerkawska, Anna Machoy-Mokrzyńska, Tadeusz Sulikowski, Łukasz Kucharski, Marta Białecka, Adam Klimowicz, Monika Białecka   +10 more
doaj   +1 more source

Systematic review and meta-analysis on the therapeutic reference range for escitalopram: Blood concentrations, clinical effects and serotonin transporter occupancy

Frontiers in Psychiatry, 2022
IntroductionA titration within a certain therapeutic reference range presupposes a relationship between the blood concentration and the therapeutic effect of a drug. However, this has not been systematically investigated for escitalopram.
Luzie Eichentopf, Christoph Hiemke, Christoph Hiemke, Andreas Conca, Andreas Conca, Jan Engelmann, Manfred Gerlach, Manfred Gerlach, Ursula Havemann-Reinecke, Ursula Havemann-Reinecke, Gudrun Hefner, Gudrun Hefner, Vincenzo Florio, Maxim Kuzin, Maxim Kuzin, Klaus Lieb, Margareta Reis, Margareta Reis, Thomas G. Riemer, Alessandro Serretti, Georgios Schoretsanitis, Georgios Schoretsanitis, Georgios Schoretsanitis, Georgios Schoretsanitis, Gerald Zernig, Gerald Zernig, Gerald Zernig, Gerhard Gründer, Gerhard Gründer, Xenia M. Hart, Xenia M. Hart   +30 more
doaj   +1 more source

Mapping Evidence of Pharmacy Services for COVID-19 in China

Frontiers in Pharmacology, 2020
ObjectiveTo explore the role of pharmacists and innovation of pharmacy interventions for COVID-19 patients in China.MethodsWe comprehensively searched PubMed and Chinese databases Sinomed, China National Knowledge Infrastructure to identify articles ...
Zhan-Miao Yi, Zhan-Miao Yi, Zhan-Miao Yi, Yang Hu, Yang Hu, Yang Hu, Yang Hu, Guan-Ru Wang, Guan-Ru Wang, Guan-Ru Wang, Guan-Ru Wang, Rong-Sheng Zhao, Rong-Sheng Zhao, Rong-Sheng Zhao   +13 more
doaj   +1 more source

Arterial Blood Pressure Variability and Other Vascular Factors Contribution to the Cognitive Decline in Parkinson’s Disease

Molecules, 2021
Dementia is one of the most disabling non-motor symptoms in Parkinson’s disease (PD). Unlike in Alzheimer’s disease, the vascular pathology in PD is less documented.
Anna Pierzchlińska, Magdalena Kwaśniak-Butowska, Jarosław Sławek, Marek Droździk, Monika Białecka   +4 more
doaj   +1 more source

Development of a Therapeutic Drug Monitoring Strategy for the Optimization of Vincristine Treatment in Pediatric Oncology Populations in Africa

, 2023
Background:Recent studies have reported ethnic differences in vincristine exposure and outcomes such as toxicity. This resulted in the hypothesis of subtherapeutic dosing in African children.
Kaspers, Gertjan J. L., Dorlo, Thomas P. C.,, Van der Heijden, Lisa T.,, Alwin D.R. Huitema, Nijstad, A. Laura, Uittenboogaard, Aniek, Beijnen, Jos H., Aniek Uittenboogaard, Beijnen, Jos H.,, Huitema, Alwin D. R., Huitema, Alwin D. R.,, van der Heijden, Lisa T., Uittenboogaard, Aniek,, Gertjan J.L. Kaspers, Dorlo, Thomas P. C., Lisa T. Van der Heijden, Kaspers, Gertjan J. L.,, Thomas P.C. Dorlo, Jos H. Beijnen, A. Laura Nijstad, Nijstad, A. Laura,   +20 more
core   +1 more source

The impact of clinical pharmacists’ intervention on the rational use of intravenous paracetamol vials in Baghdad Teaching Hospital: A case-control study [PDF]

Pharmacia
Paracetamol has been recognized worldwide as a safe and effective agent for relieving pain and reducing fever in many patients. This study aimed to investigate the role of clinical pharmacist interventions in the rational and appropriate use of ...
Kawthar Faris Nassir, Adel Hashim, Hayder A. Fawzi, Ali Saad, Osama Zuhair Salman, Zahraa R. Jabbar, Ameer A. Oudah, Aaya Ayad Okab   +7 more
doaj   +3 more sources

Rosemary and CoQ10 Alleviated the Detrimental Effects of Concomitant Administration of Acetaminophen and Carbamazepine by Accelerating Their Metabolism and Elimination

Indonesian Biomedical Journal, 2022
BACKGROUND: The interaction of carbamazepine (CBZ) and acetaminophen (APAP) could result in hepatic failure and mortality. This study was conducted to analyzed the potential of rosemary ethanol extract (REE) or coenzyme Q10 (CoQ10) to alleviate the ...
Marwa Magdy Hamido, Nashwah Ismail Zaki, Sawsan Ahmed Nasr, Wael Mohamed El-Sayed   +3 more
doaj   +1 more source