Results 21 to 30 of about 72,055 (308)

Reversible Nephrotoxicity of Colistin: A Case Report [PDF]

open access: yes, 2019
Both nosocomial and community acquired gram-negative bacterial infections cause serious morbidity and mortality. However, old antibiotics, which have toxic side effects, should be re-used because of the lack of newly developed antibiotics.
Güle Çınar   +2 more
core   +1 more source

Role of Ajwa dates in ameliorating diclofenac sodium-induced nephrotoxicity and cardiovascular risk factors in mice

open access: yesEuropean Journal of Inflammation, 2019
The study aims at evaluating the protective effects of Ajwa dates extract against diclofenac sodium (DFS)-induced nephrotoxicity. A total of 30 male albino mice were divided into three groups. Group 1 received water per oral gavage for 14 days and saline
Heba M Eltahir   +5 more
doaj   +1 more source

Protective effect of metalloporphyrins against cisplatin-induced kidney injury in mice. [PDF]

open access: yesPLoS ONE, 2014
Oxidative and nitrative stress is a well-known phenomenon in cisplatin-induced nephrotoxicity. The purpose of this work is to study the role of two metalloporphyrins (FeTMPyP and MnTBAP), water soluble complexes, in cisplatin-induced renal damage and ...
Hao Pan   +5 more
doaj   +1 more source

Determination of colistin-related nephrotoxicity and risk factors in intensive care unit

open access: yesİstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]Colistin is a cationic polypeptide antibiotic with a cyclic structure that belongs to the polymyxin group. It was banned from clinical use because of its significant renal side effects, such as nephrotoxicity.
Ayse Inci   +4 more
doaj   +1 more source

Characteristics, Influencing Factors, Predictive Scoring System, and Outcomes of the Patients with Nephrotoxicity Associated with Administration of Intravenous Colistin

open access: yesAntibiotics, 2021
Multidrug-resistant Gram-negative infection is a major global public health threat. Currently, colistin is considered the last-resort treatment despite its nephrotoxicity.
Pornpen Sangthawan   +5 more
doaj   +1 more source

Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells [PDF]

open access: yes, 2012
End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed the nephrotoxicity induced by the immunosuppressive agents’ cyclosporine A (CsA ...
Ryan, Michael P.   +7 more
core   +1 more source

A Novel Dipeptidyl Peptidase-4 Inhibitor DA-1229 Ameliorates Tubulointerstitial Fibrosis in Cyclosporine Nephrotoxicity in Mice

open access: yesLife, 2021
Cyclosporine A (CyA) is an immunosuppressive agent that induces nephrotoxicity with long-term treatment. The roles of DPP-4 and its inhibitors in cyclosporine nephrotoxicity are not fully understood.
Hye Sook Min   +7 more
doaj   +1 more source

Cisplatin Nephrotoxicity and Longitudinal Growth in Children With Solid Tumors: A Retrospective Cohort Study [PDF]

open access: yes, 2015
Cisplatin, a major antineoplastic drug used in the treatment of solid tumors, is a known nephrotoxin. This retrospective cohort study evaluated the prevalence and severity of cisplatin nephrotoxicity in 54 children and its impact on height and weight.We ...
Castañeda-Hernández, Gilberto   +11 more
core   +1 more source

Atazanavir nephrotoxicity [PDF]

open access: yesClinical Kidney Journal, 2015
Atazanavir is commonly used as one of the key drugs in combination antiretroviral therapy for human immunodeficiency virus (HIV). However, atazanavir has the potential to yield its crystalline precipitation in urine and renal interstitial tissues, leading to crystalluria, urolithiasis, acute kidney injury (AKI) or chronic kidney disease (CKD).
Hara, Masaki   +5 more
openaire   +2 more sources

Cephalosporin-Induced Nephrotoxicity: Does it Exist? [PDF]

open access: yes, 1990
The literature has been reviewed to determine whether cephalosporins have been implicated in causing nephrotoxicity and to assess the influence of concomitant aminoglycoside therapy. Animal and human data have implicated cephaloridine and cephalothin in
George G. Zhanel
core   +1 more source

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