Results 21 to 30 of about 63,588 (218)
Antimicrobial Resistance and Infection Control, 2021 Background Colistin is widely used in the treatment of nosocomial infections caused by carbapenem-resistant gram-negative bacilli (CR-GNB). Colistin-induced nephrotoxicity is one of the major adverse reactions during colistin treatment.
Jia-Yih Feng +7 more
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Protective effect of metalloporphyrins against cisplatin-induced kidney injury in mice. [PDF]
PLoS ONE, 2014 Oxidative and nitrative stress is a well-known phenomenon in cisplatin-induced nephrotoxicity. The purpose of this work is to study the role of two metalloporphyrins (FeTMPyP and MnTBAP), water soluble complexes, in cisplatin-induced renal damage and ...
Hao Pan +5 more
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European Journal of Inflammation, 2019 The study aims at evaluating the protective effects of Ajwa dates extract against diclofenac sodium (DFS)-induced nephrotoxicity. A total of 30 male albino mice were divided into three groups. Group 1 received water per oral gavage for 14 days and saline
Heba M Eltahir +5 more
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Determination of colistin-related nephrotoxicity and risk factors in intensive care unit
İstanbul Kuzey Klinikleri, 2018 INTRODUCTION[|]Colistin is a cationic polypeptide antibiotic with a cyclic structure that belongs to the polymyxin group. It was banned from clinical use because of its significant renal side effects, such as nephrotoxicity.
Ayse Inci +4 more
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Experimental Cell Line Models for Nephrotoxicity Screening
Регуляторные исследования и экспертиза лекарственных средств, 2021 The aim of the study was to review literature data on cell models for experimental assessment of drug nephrotoxicity in vitro. Because of nephrotoxicity, 2% of new investigational medicinal products are discarded at the stage of preclinical in vivo ...
I. A. Mazerkina +4 more
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Antibiotics, 2021 Multidrug-resistant Gram-negative infection is a major global public health threat. Currently, colistin is considered the last-resort treatment despite its nephrotoxicity.
Pornpen Sangthawan +5 more
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Life, 2021 Cyclosporine A (CyA) is an immunosuppressive agent that induces nephrotoxicity with long-term treatment. The roles of DPP-4 and its inhibitors in cyclosporine nephrotoxicity are not fully understood.
Hye Sook Min +7 more
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P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells. [PDF]
PLoS ONE, 2015 The pathogenesis of colistin induced nephrotoxicity is poorly understood. Currently there are no effective therapeutic or prophylactic agents available.
Sun-hyo Lee +5 more
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International Journal of Infectious DiseasesObjectives: To compare nephrotoxicity between teicoplanin and vancomycin in older patients, investigate the correlation between teicoplanin average steady-state trough concentrations (Cmin,ss) and nephrotoxicity, and identify independent risk factors for
Jionghe Wu +11 more
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Selenium alleviates porcine nephrotoxicity of ochratoxin A by improving selenoenzyme expression in vitro. [PDF]
PLoS ONE, 2015 Ochratoxin A (OTA), a mycotoxin, is a potent nephrotoxin in humans and animals. Selenium (Se) is an essential micronutrient for humans and animals, and plays a key role in antioxidant defense.
Fang Gan +4 more
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