Results 21 to 30 of about 78,162 (300)

Unveiling the mechanisms of nephrotoxicity caused by nephrotoxic compounds using toxicological network analysis

open access: yesMolecular Therapy: Nucleic Acids, 2023
Billions of people worldwide have experienced irreversible kidney injuries, which is mainly attributed to the complexity of drug-induced nephrotoxicity.
Kexing Xi   +5 more
doaj   +1 more source

Bibliometric and visual analysis of nephrotoxicity research worldwide

open access: yesFrontiers in Pharmacology, 2022
Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs.
Tianmu He   +9 more
doaj   +1 more source

Inhibition of gentamicin–induced renal tubular cell necrosis [PDF]

open access: yesJournal of Nephropathology, 2012
Gentamicin nephrotoxicity limit its usage against gram negative bacteria. Most researches showed that antioxidant agents improved gentamicin nephrotoxicity.
Majid Tavafi
doaj   +1 more source

Nephrotoxicities [PDF]

open access: yesF1000Research, 2017
Nephrotoxic medication exposure is nearly ubiquitous in hospitalized patients and represents one of the most common causes of acute kidney injury (AKI) in the hospitalized setting. Although provision of medications that are nephrotoxic has led to improved outcomes in terms of treatment of underlying illness, unnecessary nephrotoxic medication exposure ...
openaire   +2 more sources

Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat [PDF]

open access: yes, 2012
Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were ...
Hanig, J.   +23 more
core   +2 more sources

Prospective observational study of the impact of plasma colistin levels in patients with carbapenem-resistant Acinetobacter baumannii pneumonia

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Objectives: Colistin, an important drug to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections, has a narrow therapeutic window with nephrotoxicity.
Yun-Jeong Jeong   +5 more
doaj   +1 more source

Comparison of colistin-induced nephrotoxicity between two different formulations of colistin in critically ill patients: a retrospective cohort study

open access: yesAntimicrobial Resistance and Infection Control, 2021
Background Colistin is widely used in the treatment of nosocomial infections caused by carbapenem-resistant gram-negative bacilli (CR-GNB). Colistin-induced nephrotoxicity is one of the major adverse reactions during colistin treatment.
Jia-Yih Feng   +7 more
doaj   +1 more source

The Nephrotoxicity of Vancomycin [PDF]

open access: yesClinical Pharmacology & Therapeutics, 2017
Vancomycin use is often associated with nephrotoxicity. It remains uncertain, however, to what extent vancomycin is directly responsible, as numerous potential risk factors for acute kidney injury frequently coexist. Herein, we critically examine available data in adult patients pertinent to this question.
Filippone, Edward J.   +2 more
openaire   +2 more sources

Protective effect of metalloporphyrins against cisplatin-induced kidney injury in mice. [PDF]

open access: yesPLoS ONE, 2014
Oxidative and nitrative stress is a well-known phenomenon in cisplatin-induced nephrotoxicity. The purpose of this work is to study the role of two metalloporphyrins (FeTMPyP and MnTBAP), water soluble complexes, in cisplatin-induced renal damage and ...
Hao Pan   +5 more
doaj   +1 more source

Role of Ajwa dates in ameliorating diclofenac sodium-induced nephrotoxicity and cardiovascular risk factors in mice

open access: yesEuropean Journal of Inflammation, 2019
The study aims at evaluating the protective effects of Ajwa dates extract against diclofenac sodium (DFS)-induced nephrotoxicity. A total of 30 male albino mice were divided into three groups. Group 1 received water per oral gavage for 14 days and saline
Heba M Eltahir   +5 more
doaj   +1 more source

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