Results 11 to 20 of about 302,754 (340)
The Nephrotoxicity of Vancomycin [PDF]
Clinical pharmacology and therapy, 2017 Vancomycin use is often associated with nephrotoxicity. It remains uncertain, however, to what extent vancomycin is directly responsible, as numerous potential risk factors for acute kidney injury frequently coexist.
E. Filippone, W. Kraft, J. Farber
semanticscholar +3 more sources
International Journal of Molecular Sciences, 2022 Vancomycin is the most frequently used antibiotic, accounting for up to 35% of hospitalized patients with infection, because of its optimal bactericidal effectiveness and relatively low price.
Wei-Chih Kan +3 more
semanticscholar +1 more source
Vancomycin Resistance in Enterococcus and Staphylococcus aureus
Microorganisms, 2022 Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus are both common commensals and major opportunistic human pathogens. In recent decades, these bacteria have acquired broad resistance to several major classes of antibiotics, including ...
Gen Li +2 more
semanticscholar +1 more source
Intensive Care Medicine, 2022 Although dozens of studies have associated vancomycin + piperacillin–tazobactam with increased acute kidney injury (AKI) risk, it is unclear whether the association represents true injury or a pseudotoxicity characterized by isolated effects on ...
T. Miano +17 more
semanticscholar +1 more source
American Journal of Health-System Pharmacy, 2020 DOI 10.1093/ajhp/zxaa036 Michael J. Rybak, PharmD, MPH, PhD, FCCP, FIDP, FIDSA, Anti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy & Health Sciences, Wayne State University, Detroit, MI, School of ...
M. Rybak +12 more
semanticscholar +1 more source
Molecular mechanisms of vancomycin resistance
Protein Science, 2020 Vancomycin and related glycopeptides are drugs of last resort for the treatment of severe infections caused by Gram‐positive bacteria such as Enterococcus species, Staphylococcus aureus, and Clostridium difficile. Vancomycin was long considered immune to
P. Stogios, A. Savchenko
semanticscholar +1 more source
Scientific Reports, 2020 Vancomycin-resistant Staphylococcus aureus (VRSA), Vancomycin-intermediate S. aureus (VISA) and heterogeneous VISA (hVISA) are subject to vancomycin treatment failure. The aim of the present study was to determine their precise prevalence and investigate
A. Shariati +5 more
semanticscholar +1 more source
Regulation of Resistance in Vancomycin-Resistant Enterococci: The VanRS Two-Component System
Microorganisms, 2021 Vancomycin-resistant enterococci (VRE) are a serious threat to human health, with few treatment options being available. New therapeutics are urgently needed to relieve the health and economic burdens presented by VRE.
Alexandra A Guffey, P. Loll
semanticscholar +1 more source
Emerging Microbes and Infections, 2020 Vancomycin-resistant enterococci infections are of great public health significance due to limited therapeutic options. We investigated epidemiological trends and risk factors of vancomycin resistance in enterococci isolates from patients with ...
Olaniyi Ayobami +4 more
semanticscholar +1 more source
Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes [PDF]
, 2018 Objectives: Our objective was to evaluate factors associated with recurrence in patients with 027+ and 027– Clostridium difficile infection (CDI). Methods: Patients with CDI observed between January and December 2014 in six hospitals were consecutively ...
Aceti, A. +19 more
core +1 more source