Design and synthesis of modified peptide antibiotics of the vancomycin family [PDF]
, 2008 The ability of bacteria to constantly evolve new methods of resistance to antibacterial therapies represents a constant challenge in medicine. Emergence of strains of enterococci and S. Aureus that show resistance to vancomycin is an alarming phenomenon,
Bone, Philip Andrew
core +7 more sources
Evaluation of vancomycin therapy in the adult ICUs of a teaching hospital in southern Iran
Drug, Healthcare and Patient Safety, 2018 Afsaneh Vazin, Motahare Mahi Birjand, Masoud Darake Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Background: Vancomycin resistance in intensive care units (ICUs) accounts for ...
Vazin A, Mahi Birjand M, Darake M
doaj +1 more source
The Association of the mazEF Toxin-antitoxin System and Vancomycin Resistance in Clinical Isolates of Vancomycin Resistant Enterococcus faecalis [PDF]
, 2022 Vancomycin resistant enterococci are challenging bacteria as they are difficult to be eradicated. Toxin-antitoxin (TA) systems are genetic elements located in most prokaryotic genomes.
Nawal S. Gouda, Amira M. Sultan
core +1 more source
Cost-effectiveness analysis of fidaxomicin versus vancomycin in Clostridium difficile infection [PDF]
, 2014 OBJECTIVES: Fidaxomicin was non-inferior to vancomycin with respect to clinical cure rates in the treatment of Clostridium difficile infections (CDIs) in two Phase III trials, but was associated with significantly fewer recurrences than vancomycin.
Cornely, Oliver A. +5 more
core +1 more source
The Nephrotoxicity of Vancomycin [PDF]
Clinical Pharmacology & Therapeutics, 2017 Vancomycin use is often associated with nephrotoxicity. It remains uncertain, however, to what extent vancomycin is directly responsible, as numerous potential risk factors for acute kidney injury frequently coexist. Herein, we critically examine available data in adult patients pertinent to this question.
Filippone, Edward J. +2 more
openaire +2 more sources
Direct replacement of antibodies with molecularly imprinted polymer (MIP) nanoparticles in ELISA - development of a novel assay for vancomycin [PDF]
, 2013 A simple and straightforward technique for coating microplate wells with molecularly imprinted polymer nanoparticles (nanoMIPs) to develop ELISA type assays is presented here for the first time.
Guerreiro, Antonio R. +7 more
core +1 more source
Clinical Infectious Diseases, 2006 Vancomycin became available for clinical use >50 years ago but was soon discarded in favor of other antibiotics that were deemed to be more efficacious and less toxic. The advent of pseudomembranous enterocolitis, coupled with the spread of methicillin-resistant Staphylococcus aureus, led to a resurgence in the use of vancomycin.
openaire +2 more sources
Comparative genomics of vancomycin-resistant Staphylococcus aureus strains and their positions within the clade most commonly associated with methicillin-resistant S. aureus hospital-acquired infection in the United States [PDF]
, 2012 This research was supported in part with federal funds from the NIAID/NIH/DHHS, including the Harvard-wide Program on Antibiotic Resistance (NIH grant AI083214), NIH grant EY017381 (M.S.G.), contract HHSN27220090018C, and the NARSA program supported ...
Griggs, Allison +34 more
core +1 more source
Brazilian Journal of Infectious Diseases, 2015 Background: Vancomycin-resistant enterococci colonization has been reported to increase the risk of developing infections, including bloodstream infections.
Ahu Kara +8 more
doaj +1 more source
International Journal of Pediatrics, 2018 Background. Vancomycin and piperacillin-tazobactam (PTZ) are commonly used as empirical therapy for patients with health care associated infections. Vancomycin has been recognized as a nephrotoxic agent and in a few cases in the literature PTZ has been ...
Mohammed Al Nuhait +4 more
doaj +1 more source