Results 41 to 50 of about 302,754 (340)

Vancomycin-loaded chitosan aerogel particles for chronic wound applications.

Carbohydrate Polymers, 2019
Chronic wounds are a prevailing cause of decreased quality of life, being microbial burden a factor hindering the normal wound healing process. Aerogels are nanostructured materials with large surface area (>250 m2/g) and high porosity (>96%).
Clara López-Iglesias, J. Barros, I. Ardao, F. Monteiro, C. Alvarez‐Lorenzo, J. L. Gómez-Amoza, C. García-González   +6 more
semanticscholar   +1 more source

Parenterally administered vancomycin in 29 dogs and 7 cats (2003‐2017)

Journal of Veterinary Internal Medicine, 2019
Background Vancomycin is commonly used to treat resistant bacterial infections in people. Reported adverse effects of vancomycin in people include acute kidney injury (AKI), neutropenia, and systemic allergic reaction.
Ian M. DeStefano, Annie S. Wayne, Elizabeth A. Rozanski, Jonathan M. Babyak   +3 more
doaj   +1 more source

Lack of synergistic nephrotoxicity between vancomycin and piperacillin/tazobactam in a rat model and a confirmatory cellular model.

Journal of Antimicrobial Chemotherapy, 2020
BACKGROUND Vancomycin and piperacillin/tazobactam are reported in clinical studies to increase acute kidney injury (AKI). However, no clinical study has demonstrated synergistic toxicity, only that serum creatinine increases.
Gwendolyn M. Pais, Jiajun Liu, Sean N. Avedissian, Danielle Hiner, T. Xanthos, A. Chalkias, E. d’Aloja, E. Locci, A. Gilchrist, W. Prozialeck, N. Rhodes, T. Lodise, J. Fitzgerald, K. Downes, A. Zuppa, M. Scheetz   +15 more
semanticscholar   +1 more source

Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]

, 2015
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC, Bourigault, C, Holmes, A, Iucet, JC, Lepelletier, D, Moore, L, Vella, V   +6 more
core   +1 more source

Risk factors for vancomycin resistance in patients with Enterococcus faecium bloodstream infections: an analysis of the Munich Multicentric Enterococci Cohort

Microbiology Spectrum
Enterococcus faecium is difficult to treat owing to its intrinsic and acquired resistance to antibiotics, particularly vancomycin. Vancomycin-resistant Enterococcus faecium is an important cause of bloodstream infections in healthcare settings with ...
Laura Wagner, Milena Wurst, Johanna Erber, Tobias Bachfischer, Bernhard Haller, Sabine Gleich, Karl Dichtl, Roland M. Schmid, Julian Triebelhorn, Florian Voit, Ulrich Seybold, Dirk H. Busch, Patrick C. Rämer, Christoph D. Spinner, Jochen Schneider, Kathrin Rothe   +15 more
doaj   +1 more source

Iterative Chemical Engineering of Vancomycin Leads to Novel Vancomycin Analogs With a High in Vitro Therapeutic Index

Frontiers in Microbiology, 2018
Vancomycin is a glycopeptide antibiotic that inhibits transpeptidation during cell wall synthesis by binding to the D-Ala-D-Ala termini of lipid II. For long, it has been used as a last resort antibiotic.
Nigam M. Mishra, Izabela Stolarzewicz, Izabela Stolarzewicz, David Cannaerts, Joris Schuermans, Rob Lavigne, Yannick Looz, Bart Landuyt, Liliane Schoofs, Dominique Schols, Jan Paeshuyse, Peter Hickenbotham, Martha Clokie, Walter Luyten, Walter Luyten, Erik V. Van der Eycken, Erik V. Van der Eycken, Yves Briers, Yves Briers   +18 more
doaj   +1 more source

Vancomycin

Medical Clinics of North America, 1995
Vancomycin is a nontoxic glycopeptide antibiotic most often used to treat serious gram-positive infections, C. difficile diarrhea/colitis, and endocarditis and hemodialysis shunt prophylaxis. Vancomycin should not be added to drug regimens for gram-positive coverage, and the empiric use of vancomycin should be discouraged to avoid the emergence of VRE.
openaire   +2 more sources

HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.

Journal of Allergy and Clinical Immunology, 2019
BACKGROUND Vancomycin is a prevalent cause of the severe hypersensitivity syndrome drug reaction with eosinophilia and systemic symptoms (DRESS), which leads to significant morbidity and mortality and commonly occurs in the setting of combination ...
K. Konvinse, J. Trubiano, R. Pavlos, I. James, C. Shaffer, C. Bejan, R. Schutte, D. Ostrov, M. Pilkinton, M. Rosenbach, J. Zwerner, Kristina Williams, J. Bourke, P. Martinez, F. Rwandamuriye, A. Chopra, M. Watson, A. Redwood, K. White, S. Mallal, E. Phillips   +20 more
semanticscholar   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

An Unusual Case of Ototoxicity with Use of Oral Vancomycin

Case Reports in Infectious Diseases, 2018
Introduction. Systemic absorption of oral vancomycin is poor due to the size of the molecule and its pharmacokinetics. It has an elimination half life of 5–11 hours in patients with normal renal function.
Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh   +4 more
doaj   +1 more source